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flutamide and Absence Seizure

flutamide has been researched along with Absence Seizure in 5 studies

Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Research Excerpts

ExcerptRelevanceReference
"Latency and incidence of a clonic seizure were recorded."5.32Anticonvulsant effect of flutamide on seizures induced by pentylenetetrazole: involvement of benzodiazepine receptors. ( Ahmadiani, A; Mandgary, A; Sayyah, M, 2003)
" 3alpha-Androstanediol protected mice against seizures induced by GABAA receptor antagonists pentylenetetrazol, picrotoxin, and beta-carboline ester in a dose-dependent fashion."3.72Anticonvulsant activity of the testosterone-derived neurosteroid 3alpha-androstanediol. ( Reddy, DS, 2004)
"Testosterone modulates seizure susceptibility, but the underlying mechanisms are obscure."1.36The testosterone-derived neurosteroid androstanediol is a positive allosteric modulator of GABAA receptors. ( Jian, K; Reddy, DS, 2010)
"Actions at ERbeta may underlie some antiseizure effects of T's metabolites."1.35Antiseizure effects of 3alpha-androstanediol and/or 17beta-estradiol may involve actions at estrogen receptor beta. ( Frye, CA; Rhodes, M; Ryan, A, 2009)
"Latency and incidence of a clonic seizure were recorded."1.32Anticonvulsant effect of flutamide on seizures induced by pentylenetetrazole: involvement of benzodiazepine receptors. ( Ahmadiani, A; Mandgary, A; Sayyah, M, 2003)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frye, CA2
Ryan, A1
Rhodes, M1
Reddy, DS2
Jian, K1
Ahmadiani, A1
Mandgary, A1
Sayyah, M1

Reviews

1 review available for flutamide and Absence Seizure

ArticleYear
Effects and mechanisms of progestogens and androgens in ictal activity.
    Epilepsia, 2010, Volume: 51 Suppl 3

    Topics: Androgen Antagonists; Androgens; Animals; Anticonvulsants; Disease Models, Animal; Female; Flutamide

2010

Other Studies

4 other studies available for flutamide and Absence Seizure

ArticleYear
Antiseizure effects of 3alpha-androstanediol and/or 17beta-estradiol may involve actions at estrogen receptor beta.
    Epilepsy & behavior : E&B, 2009, Volume: 16, Issue:3

    Topics: Analysis of Variance; Androgen Antagonists; Androstane-3,17-diol; Animals; Anticonvulsants; Disease

2009
The testosterone-derived neurosteroid androstanediol is a positive allosteric modulator of GABAA receptors.
    The Journal of pharmacology and experimental therapeutics, 2010, Sep-01, Volume: 334, Issue:3

    Topics: Androgen Antagonists; Androstane-3,17-diol; Animals; CA1 Region, Hippocampal; Data Interpretation, S

2010
Anticonvulsant effect of flutamide on seizures induced by pentylenetetrazole: involvement of benzodiazepine receptors.
    Epilepsia, 2003, Volume: 44, Issue:5

    Topics: Amygdala; Animals; Anticonvulsants; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug In

2003
Anticonvulsant activity of the testosterone-derived neurosteroid 3alpha-androstanediol.
    Neuroreport, 2004, Mar-01, Volume: 15, Issue:3

    Topics: Androgen Antagonists; Androstane-3,17-diol; Animals; Anticonvulsants; Carbolines; Convulsants; Dose-

2004