flutamide has been researched along with Abnormalities, Drug-Induced in 7 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flutamide, which has antiandrogenic properties, was administered to pregnant rats, and effects on male offspring were examined." | 1.31 | Effects of perinatal exposure to flutamide on sex hormones and androgen-dependent organs in F1 male rats. ( Matsuo, M; Miyata, K; Nakanishi, T; Okuno, Y; Sano, M; Sukata, T; Yabushita, S; Yoshino, H, 2002) |
| "In addition, antiandrogen induced cryptorchidism is associated with epididymal malformation and failure of gubernacular regression." | 1.29 | Antiandrogen induced cryptorchidism in the pig is associated with failed gubernacular regression and epididymal malformations. ( Husmann, DA; Kramer, SA; McMahon, DR, 1995) |
| "The decrease in undescended testes and epididymal abnormalities following epidermal growth factor treatment was significant at p < 0." | 1.29 | Epidermal growth factor reverses antiandrogen induced cryptorchidism and epididymal development. ( Cain, MP; Husmann, DA; Kramer, SA; Tindall, DJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, SY | 1 |
| Liao, JW | 1 |
| Kuo, ML | 1 |
| Wang, SC | 1 |
| Hwang, JS | 1 |
| Ueng, TH | 1 |
| Yamasaki, K | 1 |
| Noda, S | 1 |
| Muroi, T | 1 |
| Mitoma, H | 1 |
| Takakura, S | 1 |
| Sakamoto, S | 1 |
| McMahon, DR | 1 |
| Kramer, SA | 3 |
| Husmann, DA | 3 |
| Cain, MP | 2 |
| Tindall, DJ | 2 |
| Mylchreest, E | 1 |
| Sar, M | 1 |
| Cattley, RC | 1 |
| Foster, PM | 1 |
| Miyata, K | 1 |
| Yabushita, S | 1 |
| Sukata, T | 1 |
| Sano, M | 1 |
| Yoshino, H | 1 |
| Nakanishi, T | 1 |
| Okuno, Y | 1 |
| Matsuo, M | 1 |
7 other studies available for flutamide and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Endocrine-disrupting activity in carbendazim-induced reproductive and developmental toxicity in rats.
Topics: Abnormalities, Drug-Induced; Androgen Antagonists; Animals; Benomyl; Benzimidazoles; Carbamates; Dos | 2004 |
Effects of in utero and lactational exposure to flutamide in SD rats: comparison of the effects of administration periods.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Fl | 2005 |
Antiandrogen induced cryptorchidism in the pig is associated with failed gubernacular regression and epididymal malformations.
Topics: Abnormalities, Drug-Induced; Animals; Cryptorchidism; Epididymis; Flutamide; Male; Swine; Testis | 1995 |
Alterations in maternal epidermal growth factor (EGF) effect testicular descent and epididymal development.
Topics: Abnormalities, Drug-Induced; Animals; Cryptorchidism; Epidermal Growth Factor; Epididymis; Female; F | 1994 |
Epidermal growth factor reverses antiandrogen induced cryptorchidism and epididymal development.
Topics: Abnormalities, Drug-Induced; Animals; Cryptorchidism; Epidermal Growth Factor; Epididymis; Female; F | 1994 |
Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide.
Topics: Abnormalities, Drug-Induced; Androgen Antagonists; Androgens; Animals; Animals, Newborn; Cryptorchid | 1999 |
Effects of perinatal exposure to flutamide on sex hormones and androgen-dependent organs in F1 male rats.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Androgen Antagonists; Animals; Animals, Newborn; | 2002 |