flurothyl has been researched along with Disease Models, Animal in 62 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (8.06) | 18.7374 |
1990's | 3 (4.84) | 18.2507 |
2000's | 26 (41.94) | 29.6817 |
2010's | 23 (37.10) | 24.3611 |
2020's | 5 (8.06) | 2.80 |
Authors | Studies |
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Greenberg, DA; McCarthy, E; Miller, J; Morris Cameron, E; Pathak, S; Saint Ange, P; Shakil, F; Velíšek, L; Velíšková, J | 1 |
Binder, MS; Kim, AD; Lugo, JN | 1 |
Bell, TA; Dalton, KA; Gu, B; Hock, P; Miller, DR; Pan, Y; Pardo-Manuel de Villena, F; Philpot, BD; Shaw, GD; Shorter, JR; Williams, LH | 1 |
Egawa, K; Goto, T; Kimura, S; Manabe, A; Nakakubo, S; Shiraishi, H | 1 |
Binder, MS; Condon, SM; Darner, AM; Faust, AM; Hodges, SL; Kwok, EM; Lugo, JN; Nolan, SO; Quintero, SI; Senger, SS; Womble, PD | 1 |
Dutt, K; Dutton, SBB; Escayg, A; Goldin, AL; Helmers, S; Papale, LA | 1 |
Matthews, SA; Simeone, KA; Simeone, TA | 1 |
Beyer, BS; Ferland, RJ; Gracias, J; Hains, L; Herron, BJ; Kadiyala, SB; Kang, EY; O'Brien, B; Papandrea, D; Smith, J | 1 |
Borges, K; Durie, D; McDonald, TS | 1 |
Jin, MF; Li, LL; Li, YC; Ni, H; Zhao, DJ | 1 |
Arehart, E; Hyder, SN; Kolls, BJ; Leonard, AS; Mikati, MA; Ng, KC; Veerapandiyan, A | 1 |
Alvarez, PS; Hemb, M; Nunes, ML; Simão, F; Xavier, LL | 1 |
Xiong, Y; Zhang, L; Zhou, H | 1 |
Ferland, RJ; Herron, BJ; Kadiyala, SB; Papandrea, D | 1 |
Adil, SM; Arehart, E; Fainberg, NA; Forbes, SL; Helseth, AR; Hochgeschwender, U; Hochman, DW; Hunanyan, AS; Kibbi, N; Leonard, AS; Linabarger, M; Mikati, MA; Rhodes, T; Rodriguiz, RM; Swearingen, AK; Wetsel, WC; Yao, X | 1 |
Anderson, TM; Ferland, RJ; Herron, BJ; Jayakumar, S; Kadiyala, SB; Papandrea, D; Tuz, K | 1 |
Jellett, AP; Jenks, K; Lucas, M; Scott, RC | 1 |
Borges, K; Carrasco-Pozo, C; Tan, KN | 1 |
Beyer, BS; Ferland, RJ; Herron, BJ; Kadiyala, SB; Nalwalk, JW; Papandrea, D; Yannix, JQ | 1 |
Hu, Q; Li, X; Liu, L; Mao, D; Shi, J; Tan, M; Xiong, J; Yi, Z | 1 |
Matthews, SA; Samson, KK; Simeone, KA; Simeone, TA | 1 |
Borges, K; Denhardt, DT; Dingledine, R; Gearing, M; Kotloski, R; Rittling, S; Sorensen, ES | 1 |
Anderson, TM; Ferland, RJ; Herron, BJ; Papandrea, D | 1 |
Jiang, YW; Jin, MF; Ni, H; Tao, LY; Wu, XR | 1 |
Brooks-Kayal, AR; Cooper, EC; Keating, JG; Lapides, DA; Raol, YH | 1 |
Holmes, GL; Huang, LT; Karnam, HB; Shatskikh, T; Zhao, Q; Zhou, JL | 1 |
Paz, C; Retana-Márquez, S; Rubio, C; Rubio-Osornio, M; Verónica Custodio, ML | 1 |
Holmes, GL; Lenck-Santini, PP; Lucas, MM; Scott, RC | 1 |
Borges, K; Catterall, WA; Dutton, SB; Escayg, A; Jumbo-Lucioni, P; Kalume, F; Sawyer, NT | 1 |
Hernan, AE; Holmes, GL; Kleen, JK; Miller, FA; Scott, RC; Sesqué, A; Wu, EX | 1 |
Deykun, K; Krýsl, D; Mareš, J; Pometlová, M; Rokyta, R | 1 |
Fox, SE; Hangya, B; Lin, H; Muller, RU | 1 |
Nunes, ML; Porto, JA; Simão, F | 1 |
Applegate, CD; Kriscenski-Perry, E; Leonardo, CC; Mhyre, TR; Pearce, DA; Serour, A | 1 |
Cha, BH; Holmes, GL; Hu, Y; Liu, X; Silveira, DC | 1 |
Applegate, CD; Ferland, RJ; Gross, RA | 1 |
Applegate, CD; Ferland, RJ; Gross, RA; Williams, JP | 1 |
Applegate, CD; Mhyre, TR | 1 |
Emmi, A; Patel, LS; Robbins, CA; Schwartzkroin, PA; Wenzel, HJ; Yeung, RS | 1 |
Bo, T; Cao, H; Jiang, Y; Wang, J; Wu, X | 1 |
Giorgi, FS; Hasson, H; Malhotra, S; Moshé, SL; Rosenbaum, DM; Velísková, J | 1 |
Brown, LL; Miller, AM; Nunes, ML; Velísková, J | 1 |
Liles, LC; Schank, JR; Weinshenker, D | 1 |
Ahern, TH; Eagles, DA; Javors, MA; Liles, LC; Martillotti, J; Mitchell, HA; Weinshenker, D | 1 |
Bo, T; Liu, LQ; Mao, DA | 1 |
Holmes, GL; Lenck-Santini, PP; Zhao, Q; Zhou, JL | 1 |
Fisher, RS; Kraus, AC; Oommen, J | 1 |
Bo, T; Chen, Y; Li, YF; Mao, DA; Zhu, XH | 1 |
Holmes, GL; Liu, X; Shatskikh, TN; Zhou, JL | 1 |
Browning, RA; Simonton, RL; Turner, FJ | 1 |
Applegate, CD; Ozduman, K; Samoriski, GM | 1 |
Applegate, CD; Ferland, RJ | 2 |
Woolley, CS | 1 |
Liptáková, S; Moshé, SL; Velísek, L; Velísková, J | 1 |
Robbins, CA; Schwartzkroin, PA; Tsai, LH; Wenzel, HJ | 1 |
Cha, BH; Cilio, MR; Holmes, GL; Liu, X; McCabe, BK; Silveira, DC; Sogawa, Y | 1 |
Moshé, SL; Velísek, L; Velísková, J | 1 |
Holaday, JW; Robles, L; Tortella, FC | 1 |
Albala, BJ; Moshé, SL | 1 |
Mettler, FA; Sax, DS | 1 |
Racusen, LC; Smith, DB | 1 |
1 review(s) available for flurothyl and Disease Models, Animal
Article | Year |
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In vivo experimental models of epilepsy.
Topics: Aluminum Hydroxide; Animals; Bicuculline; Cobalt; Convulsants; Disease Models, Animal; Electroshock; Epilepsy; Epilepsy, Reflex; Flurothyl; gamma-Aminobutyric Acid; Humans; Kainic Acid; Kindling, Neurologic; Muscarinic Agonists; Papio; Penicillins; Pentylenetetrazole; Pilocarpine; Tetanus Toxin; Zinc Compounds | 2010 |
61 other study(ies) available for flurothyl and Disease Models, Animal
Article | Year |
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Developmental decrease in parvalbumin-positive neurons precedes increase in flurothyl-induced seizure susceptibility in the Brd2
Topics: Androstenedione; Animals; Disease Models, Animal; Female; Flurothyl; GABAergic Neurons; Male; Mice; Mice, Inbred C57BL; Myoclonic Epilepsy, Juvenile; Neurons; Parvalbumins; Seizures; Testosterone Propionate; Transcription Factors | 2020 |
An acute seizure prior to memory reactivation transiently impairs associative memory performance in C57BL/6J mice.
Topics: Animals; Association Learning; Behavior, Animal; Conditioning, Classical; Convulsants; Disease Models, Animal; Fear; Female; Flurothyl; Male; Memory Disorders; Mice, Inbred C57BL; Seizures; Time Factors | 2020 |
Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility.
Topics: Animals; Chromosome Mapping; Collaborative Cross Mice; Convulsants; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Flurothyl; Gene Expression; Gene Expression Profiling; Genetic Predisposition to Disease; Genotype; Hippocampus; Kainic Acid; Mice; Mice, Inbred Strains; Pentylenetetrazole; Phenotype; Quantitative Trait Loci; Seizures; Sudden Unexpected Death in Epilepsy; Whole Genome Sequencing | 2020 |
Flurothyl-induced seizure paradigm revealed higher seizure susceptibility in middle-aged Angelman syndrome mouse model.
Topics: Angelman Syndrome; Animals; Disease Models, Animal; Disease Susceptibility; Flurothyl; Male; Mice; Seizures; Tetrazoles; Ubiquitin-Protein Ligases | 2021 |
Rapamycin, but not minocycline, significantly alters ultrasonic vocalization behavior in C57BL/6J pups in a flurothyl seizure model.
Topics: Animals; Convulsants; Disease Models, Animal; Epilepsy; Female; Flurothyl; Immunologic Factors; Male; Mice; Mice, Inbred C57BL; Minocycline; MTOR Inhibitors; Seizures; Sex Factors; Sirolimus; Vocalization, Animal | 2021 |
Early-life febrile seizures worsen adult phenotypes in Scn1a mutants.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Arginine; Convulsants; Disease Models, Animal; Disease Progression; Exploratory Behavior; Female; Flurothyl; Hippocampus; Histidine; Humans; Hyperthermia, Induced; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; NAV1.1 Voltage-Gated Sodium Channel; Phenotype; Reaction Time; Recognition, Psychology; Seizures, Febrile | 2017 |
Synergistic protection against acute flurothyl-induced seizures by adjuvant treatment of the ketogenic diet with the type 2 diabetes drug pioglitazone.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Weight; Convulsants; Diet, Ketogenic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Flurothyl; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Pioglitazone; Reaction Time; Seizures; Thiazolidinediones | 2017 |
Multidimensional Genetic Analysis of Repeated Seizures in the Hybrid Mouse Diversity Panel Reveals a Novel Epileptogenesis Susceptibility Locus.
Topics: Alleles; Animals; Brain; Chromosomes, Mammalian; Crosses, Genetic; Disease Models, Animal; Epilepsy; Epistasis, Genetic; Female; Flurothyl; Genetic Loci; Genetic Predisposition to Disease; Genetic Variation; Genome-Wide Association Study; Kindling, Neurologic; Male; Mice; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Regression Analysis; Seizures | 2017 |
The effect of dichloroacetate in mouse models of epilepsy.
Topics: Analysis of Variance; Animals; Anticonvulsants; Convulsants; Dichloroacetic Acid; Disease Models, Animal; Electric Stimulation; Epilepsy; Flurothyl; Ketone Oxidoreductases; Male; Mice; Mitochondria; Pilocarpine | 2018 |
Leptin-regulated autophagy plays a role in long-term neurobehavioral injury after neonatal seizures and the regulation of zinc/cPLA2 and CaMK II signaling in cerebral cortex.
Topics: Animals; Animals, Newborn; Autophagy; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carrier Proteins; Cerebral Cortex; Disease Models, Animal; Flurothyl; Group IV Phospholipases A2; Leptin; Male; Motor Activity; Neuroprotection; Neuroprotective Agents; Random Allocation; Rats, Sprague-Dawley; Seizures; Signal Transduction | 2018 |
Seizure predisposition after perinatal hypoxia: effects of subsequent age and of an epilepsy predisposing gene mutation.
Topics: Age Factors; Animals; Animals, Newborn; Disease Models, Animal; Electroencephalography; Flurothyl; Genetic Predisposition to Disease; Heterozygote; Hippocampus; Humans; Hypoxia; Kindling, Neurologic; Kv1.1 Potassium Channel; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Seizures | 2013 |
Effects of undernourishment, recurrent seizures and enriched environment during early life in hippocampal morphology.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Cell Count; Convulsants; Disease Models, Animal; Environment; Female; Flurothyl; Hippocampus; Male; Malnutrition; Neuroglia; Neurons; Pregnancy; Rats; Rats, Wistar; Seizures | 2014 |
Influences of hyperthermia-induced seizures on learning, memory and phosphorylative state of CaMKIIα in rat hippocampus.
Topics: Animals; Blotting, Western; Calcium-Binding Proteins; Carrier Proteins; Convulsants; Disease Models, Animal; Flurothyl; Hippocampus; Hot Temperature; Male; Maze Learning; Memory; Neurons; Neuropsychological Tests; Phosphorylation; Physical Stimulation; Post-Synaptic Density; Rats; Rats, Sprague-Dawley; Seizures; Seizures, Febrile; Space Perception | 2014 |
Segregation of seizure traits in C57 black mouse substrains using the repeated-flurothyl model.
Topics: Analysis of Variance; Animals; Crosses, Genetic; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Flurothyl; Male; Mice; Mice, Inbred C57BL; Seizures; Species Specificity | 2014 |
Knock-in mouse model of alternating hemiplegia of childhood: behavioral and electrophysiologic characterization.
Topics: Amygdala; Animals; Behavior, Animal; Brain; Convulsants; Disease Models, Animal; Electroencephalography; Electrophysiological Phenomena; Flurothyl; Gene Knock-In Techniques; Hemiplegia; Kindling, Neurologic; Learning; Locomotion; Memory; Mice; Mice, Transgenic; Seizures; Sodium-Potassium-Exchanging ATPase | 2015 |
Spatiotemporal differences in the c-fos pathway between C57BL/6J and DBA/2J mice following flurothyl-induced seizures: A dissociation of hippocampal Fos from seizure activity.
Topics: Animals; Blotting, Western; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Extracellular Signal-Regulated MAP Kinases; Flurothyl; Gene Expression; Genetic Predisposition to Disease; Hippocampus; Immunohistochemistry; Male; Mice, Inbred C57BL; Mice, Inbred DBA; Proto-Oncogene Proteins c-fos; Seizures; Species Specificity | 2015 |
Standard dose valproic acid does not cause additional cognitive impact in a rodent model of intractable epilepsy.
Topics: Animals; Animals, Newborn; Anticonvulsants; Cognition; Cognition Disorders; Disease Models, Animal; Epilepsy; Female; Flurothyl; Hippocampus; Malformations of Cortical Development; Maze Learning; Methylazoxymethanol Acetate; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley; Seizures; Survival Analysis; Valproic Acid | 2015 |
Sulforaphane is anticonvulsant and improves mitochondrial function.
Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electron Transport Complex I; Electroshock; Epilepsy; Flurothyl; Hippocampus; Isothiocyanates; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mitochondria; Nerve Degeneration; Oxidative Stress; Pentylenetetrazole; Pilocarpine; Sulfoxides; Superoxide Dismutase | 2015 |
Eight Flurothyl-Induced Generalized Seizures Lead to the Rapid Evolution of Spontaneous Seizures in Mice: A Model of Epileptogenesis with Seizure Remission.
Topics: Analysis of Variance; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Fluoresceins; Flurothyl; Hippocampus; Male; Mice; Mice, Inbred C57BL; Seizures; Time Factors; Video Recording | 2016 |
MicroRNA-34b mediates hippocampal astrocyte apoptosis in a rat model of recurrent seizures.
Topics: Animals; Apoptosis; Astrocytes; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cells, Cultured; Disease Models, Animal; Flurothyl; Hippocampus; In Situ Nick-End Labeling; Kainic Acid; Microarray Analysis; MicroRNAs; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Transcriptome | 2016 |
Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy.
Topics: 3-Hydroxybutyric Acid; Age Factors; Anilides; Animals; Animals, Newborn; Anticonvulsants; Blood Glucose; Brain; Convulsants; Diet, Ketogenic; Disease Models, Animal; Drinking; Epilepsy; Flurothyl; Gene Expression Regulation, Developmental; Hypoglycemic Agents; Kv1.1 Potassium Channel; Mice; Mice, Inbred C57BL; Mice, Knockout; Pioglitazone; PPAR gamma; Thiazolidinediones | 2017 |
Characterization of osteopontin expression and function after status epilepticus.
Topics: Animals; CD11b Antigen; Cell Degranulation; Cells, Cultured; Disease Models, Animal; Electroshock; Embryo, Mammalian; Excitatory Amino Acid Agonists; Flurothyl; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hyaluronan Receptors; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Nitric Oxide Synthase Type II; Osteopontin; Pilocarpine; Prosencephalon; RNA, Messenger; Status Epilepticus | 2008 |
Dissociation of seizure traits in inbred strains of mice using the flurothyl kindling model of epileptogenesis.
Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Epilepsy; Flurothyl; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Phenotype; Reaction Time; Species Specificity | 2009 |
ZnT-1, ZnT-3, CaMK II, PRG-1 expressions in hippocampus following neonatal seizure-induced cognitive deficit in rats.
Topics: Age Factors; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin-Binding Proteins; Cation Transport Proteins; Cognition; Cognition Disorders; Disease Models, Animal; Flurothyl; Hippocampus; Male; Maze Learning; Membrane Proteins; Memory; Mossy Fibers, Hippocampal; Phosphoric Monoester Hydrolases; Rats; Rats, Sprague-Dawley; Reaction Time; Recurrence; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seizures; Spatial Behavior; Staining and Labeling | 2009 |
A KCNQ channel opener for experimental neonatal seizures and status epilepticus.
Topics: Aminopyridines; Animals; Animals, Newborn; Anticonvulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Female; Flurothyl; Kainic Acid; KCNQ Potassium Channels; Male; Phenobarbital; Pregnancy; Rats; Seizures; Spectrum Analysis; Status Epilepticus; Time Factors | 2009 |
Early life seizures cause long-standing impairment of the hippocampal map.
Topics: Action Potentials; Age Factors; Aging; Animals; Brain Mapping; Cognition Disorders; Convulsants; Disease Models, Animal; Epilepsy; Flurothyl; Hippocampus; Male; Maze Learning; Memory Disorders; Nerve Degeneration; Orientation; Rats; Rats, Sprague-Dawley; Space Perception; Time | 2009 |
Impaired cognition in rats with cortical dysplasia: additional impact of early-life seizures.
Topics: Age Factors; Animals; Animals, Newborn; Cognition Disorders; Disease Models, Animal; Embryo, Mammalian; Female; Flurothyl; Hippocampus; Malformations of Cortical Development; Maze Learning; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures | 2011 |
Protective effect of the ketogenic diet in Scn1a mutant mice.
Topics: 3-Hydroxybutyric Acid; Animals; Convulsants; Diet, Ketogenic; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Generalized; Epithelial Sodium Channels; Flurothyl; Mice; Mice, Knockout; Seizures; Weight Gain | 2011 |
Early-life seizures produce lasting alterations in the structure and function of the prefrontal cortex.
Topics: Animals; Animals, Newborn; Conditioning, Operant; Disease Models, Animal; Electroencephalography; Flurothyl; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Seizures | 2011 |
An isolated epileptic seizure elicits learning impairment which could be prevented by melatonin.
Topics: Analysis of Variance; Animals; Antioxidants; Automatism; Blood-Brain Barrier; Convulsants; Disease Models, Animal; Flurothyl; Hypoxia; Learning Disabilities; Male; Maze Learning; Melatonin; Rats; Reaction Time; Seizures; Time Factors | 2012 |
Repetitive convulsant-induced seizures reduce the number but not precision of hippocampal place cells.
Topics: Action Potentials; Animals; Brain Mapping; Brain Waves; Convulsants; Disease Models, Animal; Drug Administration Schedule; Electrodes, Implanted; Electroencephalography; Fasting; Flurothyl; Hippocampus; Male; Models, Neurological; Neurons; Rats; Rats, Long-Evans; Seizures; Statistics, Nonparametric; Time Factors | 2012 |
Effects of enriched environment in spatial learning and memory of immature rats submitted to early undernourish and seizures.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Convulsants; Disease Models, Animal; Environment; Female; Flurothyl; Male; Malnutrition; Maze Learning; Pregnancy; Rats; Reaction Time; Retention, Psychology; Seizures; Spatial Behavior; Time Factors | 2012 |
Altered flurothyl seizure induction latency, phenotype, and subsequent mortality in a mouse model of juvenile neuronal ceroid lipofuscinosis/batten disease.
Topics: Administration, Inhalation; Age Factors; Animals; Disease Models, Animal; Flurothyl; Humans; Membrane Glycoproteins; Mice; Mice, Neurologic Mutants; Molecular Chaperones; Neuronal Ceroid-Lipofuscinoses; Phenotype; Proteins; Seizures | 2002 |
Effect of topiramate following recurrent and prolonged seizures during early development.
Topics: Animals; Animals, Newborn; Anticonvulsants; Body Weight; Cell Death; Cognition; Convulsants; Disease Models, Animal; Epilepsy; Flurothyl; Fructose; Hippocampus; Lithium; Maze Learning; Mossy Fibers, Hippocampal; Muscarinic Agonists; Nerve Degeneration; Pilocarpine; Rats; Rats, Sprague-Dawley; Reaction Time; Recurrence; Research Design; Topiramate | 2002 |
Increased mitotic activity in the dentate gyrus of the hippocampus of adult C57BL/6J mice exposed to the flurothyl kindling model of epileptogenesis.
Topics: Animals; Bromodeoxyuridine; Cell Count; Convulsants; Dentate Gyrus; Disease Models, Animal; Epilepsy; Flurothyl; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Mitosis; Neuroglia; Neurons; Phenotype; Stem Cells; Up-Regulation | 2002 |
The effects of brain-irradiation-induced decreases in hippocampal mitotic activity on flurothyl-induced epileptogenesis in adult C57BL/6J mice.
Topics: Animals; Behavior, Animal; Brain; Bromodeoxyuridine; Cell Count; Cell Division; Convulsants; Dentate Gyrus; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Flurothyl; Gamma Rays; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mitosis | 2003 |
Persistent regional increases in brain-derived neurotrophic factor in the flurothyl model of epileptogenesis are dependent upon the kindling status of the animal.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Epilepsy; Flurothyl; Immunohistochemistry; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Models, Neurological; Phenotype; Receptor, trkB; Signal Transduction; Up-Regulation | 2003 |
Morphology of cerebral lesions in the Eker rat model of tuberous sclerosis.
Topics: Animals; Astrocytes; Cerebral Cortex; Disease Models, Animal; Flurothyl; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Immunohistochemistry; Intermediate Filament Proteins; Isoenzymes; Microscopy, Immunoelectron; Microtubule-Associated Proteins; Nerve Tissue Proteins; Nestin; Neurofilament Proteins; Neurons; Phosphopyruvate Hydratase; Rats; Rats, Inbred F344; Rats, Mutant Strains; Reaction Time; Repressor Proteins; Seizures; Staining and Labeling; Tuberous Sclerosis; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Whole-Body Irradiation | 2004 |
Long-term effects of seizures in neonatal rats on spatial learning ability and N-methyl-D-aspartate receptor expression in the brain.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Convulsants; Disease Models, Animal; Female; Flurothyl; Glutamic Acid; Hippocampus; Learning Disabilities; Male; Maze Learning; Memory Disorders; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; Seizures; Space Perception; Synaptic Transmission; Telencephalon; Time Factors | 2004 |
Effects of status epilepticus early in life on susceptibility to ischemic injury in adulthood.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Disease Susceptibility; Electroencephalography; Flurothyl; Infarction, Middle Cerebral Artery; Kainic Acid; Male; Monitoring, Physiologic; Neocortex; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Status Epilepticus; Stroke | 2005 |
Regional neural activity within the substantia nigra during peri-ictal flurothyl generalized seizure stages.
Topics: Action Potentials; Animals; Autoradiography; Brain Mapping; Convulsants; Deoxyglucose; Disease Models, Animal; Energy Metabolism; Epilepsy; Flurothyl; Male; Neural Inhibition; Neural Pathways; Neurons; Pedunculopontine Tegmental Nucleus; Rats; Rats, Sprague-Dawley; Substantia Nigra; Superior Colliculi; Synaptic Transmission; Ventral Thalamic Nuclei | 2005 |
Reduced anticonvulsant efficacy of valproic acid in dopamine beta-hydroxylase knockout mice.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Anticonvulsants; Disease Models, Animal; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Drug Combinations; Flurothyl; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Norepinephrine; Reaction Time; Reboxetine; Seizures; Valproic Acid | 2005 |
The effects of chronic norepinephrine transporter inactivation on seizure susceptibility in mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Disease Models, Animal; Dopamine beta-Hydroxylase; Drug Administration Schedule; Electroshock; Flurothyl; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Norepinephrine Plasma Membrane Transport Proteins; Pentylenetetrazole; Reaction Time; Reboxetine; Seizures | 2006 |
[Expression and significance of caspase-1, IL-18 and IL-1beta in the hippocampus of the developing recurrent seizures rats].
Topics: Animals; Caspase 1; Disease Models, Animal; Female; Flurothyl; Gene Expression Regulation; Hippocampus; Interleukin-18; Interleukin-1beta; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seizures; Time Factors; Up-Regulation | 2006 |
Effect of interictal spikes on single-cell firing patterns in the hippocampus.
Topics: Action Potentials; Animals; Behavior, Animal; Disease Models, Animal; Electroencephalography; Flurothyl; Hippocampus; Interneurons; Lithium Compounds; Male; Microelectrodes; Neurons; Patch-Clamp Techniques; Pilocarpine; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Seizures; Spatial Behavior; Walking | 2007 |
Intraventricular administration of gabapentin in the rat increases flurothyl seizure threshold.
Topics: Amines; Animals; Anticonvulsants; Brain; Brain Chemistry; Cerebral Cortex; Convulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Epilepsy; Flurothyl; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraventricular; Methylene Blue; Nerve Fibers, Myelinated; Rats; Rats, Sprague-Dawley; Seizures; Staining and Labeling; Time Factors; Treatment Outcome | 2007 |
[Long-term effects of recurrent seizures in neonate period on gamma-aminobutyric acid A receptor alpha1 and beta2 subunits expression in adult brain: experiment with rats].
Topics: Animals; Animals, Newborn; Brain; Cerebral Cortex; Disease Models, Animal; Flurothyl; Hippocampus; Immunohistochemistry; Maze Learning; Pentylenetetrazole; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seizures; Time Factors | 2007 |
Impaired single cell firing and long-term potentiation parallels memory impairment following recurrent seizures.
Topics: Action Potentials; Animals; Brain Mapping; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Electroencephalography; Flurothyl; Long-Term Potentiation; Male; Maze Learning; Memory Disorders; Neurons; Rats; Rats, Sprague-Dawley; Seizures; Spatial Behavior; Spectrum Analysis; Swimming; Time Factors | 2007 |
Antagonism of experimentally induced tonic seizures following a lesion in the midbrain tegmentum.
Topics: Animals; Disease Models, Animal; Electroshock; Flurothyl; Hindlimb; Male; Muscles; Pentylenetetrazole; Rats; Seizures; Tegmentum Mesencephali | 1981 |
Effects of valproate, phenytoin, and MK-801 in a novel model of epileptogenesis.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain Stem; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Flurothyl; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neural Pathways; Phenytoin; Valproic Acid | 1997 |
Decreased brainstem seizure thresholds and facilitated seizure propagation in mice exposed to repeated flurothyl-induced generalized forebrain seizures.
Topics: Animals; Brain Stem; Cornea; Disease Models, Animal; Electroshock; Flurothyl; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Olfactory Bulb; Prosencephalon; Seizures | 1998 |
Bidirectional transfer between electrical and flurothyl kindling in mice: evidence for common processes in epileptogenesis.
Topics: Animals; Brain Stem; Disease Models, Animal; Disease Susceptibility; Electric Stimulation; Electrodes, Implanted; Epilepsy; Flurothyl; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Olfactory Bulb; Prosencephalon | 1999 |
Estradiol facilitates kainic acid-induced, but not flurothyl-induced, behavioral seizure activity in adult female rats.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Drug Interactions; Estradiol; Female; Flurothyl; Hippocampus; Humans; Kainic Acid; Limbic System; Male; Neural Pathways; Progesterone; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Seizures | 2000 |
Effect of ganaxolone on flurothyl seizures in developing rats.
Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Flurothyl; Male; Motor Activity; Pregnanolone; Rats; Rats, Sprague-Dawley; Seizures | 2000 |
Abnormal morphological and functional organization of the hippocampus in a p35 mutant model of cortical dysplasia associated with spontaneous seizures.
Topics: Animals; Astrocytes; Behavior, Animal; Cell Count; Cytoplasmic Granules; Disease Models, Animal; Electroencephalography; Epilepsy; Excitatory Postsynaptic Potentials; Flurothyl; Hippocampus; Homozygote; Immunohistochemistry; Interneurons; Lysine; Mice; Mice, Knockout; Mossy Fibers, Hippocampal; Neocortex; Nerve Tissue Proteins; Nervous System Malformations; Pyramidal Cells; Reaction Time; Sensory Thresholds | 2001 |
Reduced neurogenesis after neonatal seizures.
Topics: Acidosis; Age Factors; Animals; Animals, Newborn; Brain; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Division; Dentate Gyrus; Disease Models, Animal; Fluorescent Antibody Technique; Flurothyl; Hypercapnia; Hypoxia; Immunohistochemistry; Male; Neurons; Rats; Rats, Sprague-Dawley; Seizures | 2001 |
Electrical stimulation of substantia nigra pars reticulata is anticonvulsant in adult and young male rats.
Topics: Age Factors; Animals; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation Therapy; Electrodes, Implanted; Flurothyl; Male; Rats; Rats, Sprague-Dawley; Seizures; Substantia Nigra; Treatment Outcome | 2002 |
U50,488, a highly selective kappa opioid: anticonvulsant profile in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Flurothyl; Male; Phenytoin; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Seizures | 1986 |
Perinatal hypoxia and subsequent development of seizures.
Topics: Animals; Asphyxia Neonatorum; Disease Models, Animal; Disease Susceptibility; Epilepsies, Partial; Epilepsy; Flurothyl; Kindling, Neurologic; Rats; Rats, Inbred Strains | 1985 |
Cerebellar cortical degeneration due to acute azide poisoning.
Topics: Animals; Azides; Cerebellar Ataxia; Cerebellar Cortex; Cerebral Decortication; Disease Models, Animal; Dose-Response Relationship, Drug; Flurothyl; Haplorhini; Macaca; Respiration, Artificial; Seizures; Succinylcholine; Thiamylal | 1972 |
Folate metabolism and the anticonvulsant efficacy of phenobarbital.
Topics: Animals; Disease Models, Animal; Flurothyl; Folic Acid; Folic Acid Deficiency; Male; Phenobarbital; Rats; Seizures; Vitamin B 12 | 1973 |