Page last updated: 2024-10-27

flurbiprofen and Uremia

flurbiprofen has been researched along with Uremia in 2 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
" The disposition of flurbiprofen enantiomers was not changed upon multiple dosing and no evidence of futile cycling was found."1.28Stereoselective disposition of flurbiprofen in uraemic patients. ( Brater, DC; Hall, SD; Knadler, MP, 1992)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Knadler, MP2
Brater, DC2
Hall, SD2

Other Studies

2 other studies available for flurbiprofen and Uremia

ArticleYear
Stereoselective disposition of flurbiprofen in uraemic patients.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:4

    Topics: Aged; Blood Proteins; Female; Flurbiprofen; Humans; Male; Middle Aged; Protein Binding; Stereoisomer

1992
Plasma protein binding of flurbiprofen: enantioselectivity and influence of pathophysiological status.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Blood Proteins; Flurbiprofen; Humans;

1989