flurbiprofen has been researched along with Ulcer in 9 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gastric ulcers were induced in rats by serosal application of acetic acid." | 1.31 | Divergent effects of new cyclooxygenase inhibitors on gastric ulcer healing: Shifting the angiogenic balance. ( del Soldato, P; Ma, L; Wallace, JL, 2002) |
| " Dose-response for intestinal ulcer production was observed for rac- and (S)-flurbiprofen; animals given (R)-flurbiprofen exhibited no ulcers." | 1.30 | Mechanism of enhancement of intestinal ulcerogenicity of S-aryl propionic acids by their R-enantiomers in the rat. ( Gibson, K; Kantoci, D; Leipold, D; Liu, Y; McCracken, JD; Mineyama, Y; Murray, ED; Quiggle, D; Wechter, WJ, 1998) |
| "Esophagography revealed an esophageal stenosis which was considered to be caused by the extramural compression on the oral side of the ulcers." | 1.28 | [A case of drug-induced esophageal ulcer developed at the esophageal constriction due to the right aortic arch]. ( Akaike, M; Amano, T; Imada, T; Kubo, A; Matsumoto, A; Takehana, T, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amir, M | 1 |
| Kumar, H | 1 |
| Javed, SA | 1 |
| Ma, L | 1 |
| del Soldato, P | 1 |
| Wallace, JL | 1 |
| Healy, CM | 1 |
| Thornhill, MH | 1 |
| Wechter, WJ | 4 |
| Bigornia, AE | 1 |
| Murray, ED | 4 |
| Levine, BH | 1 |
| Young, JW | 1 |
| Kantoci, D | 3 |
| Quiggle, DD | 2 |
| Leipold, DD | 2 |
| Gibson, KM | 2 |
| McCracken, JD | 3 |
| Quiggle, D | 1 |
| Leipold, D | 1 |
| Gibson, K | 1 |
| Mineyama, Y | 1 |
| Liu, Y | 1 |
| Bertrand, V | 1 |
| Guimbaud, R | 1 |
| Sogni, P | 1 |
| Lamrani, A | 1 |
| Mauprivez, C | 1 |
| Giroud, JP | 1 |
| Couturier, D | 1 |
| Chauvelot-Moachon, L | 1 |
| Chaussade, S | 1 |
| Takehana, T | 1 |
| Imada, T | 1 |
| Kubo, A | 1 |
| Akaike, M | 1 |
| Amano, T | 1 |
| Matsumoto, A | 1 |
9 other studies available for flurbiprofen and Ulcer
| Article | Year |
|---|---|
Condensed bridgehead nitrogen heterocyclic system: synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid.
Topics: Acute Disease; Analgesics; Animals; Bacteria; Diphenylacetic Acids; Female; Fungi; Hepatocytes; Ibup | 2008 |
Divergent effects of new cyclooxygenase inhibitors on gastric ulcer healing: Shifting the angiogenic balance.
Topics: Animals; Apoptosis; Cell Division; Cells, Cultured; Collagen; Cyclooxygenase Inhibitors; Endostatins | 2002 |
An association between recurrent oro-genital ulceration and non-steroidal anti-inflammatory drugs.
Topics: Diclofenac; Drug Hypersensitivity; Female; Flurbiprofen; Genital Diseases, Female; Humans; Middle Ag | 1995 |
Rac-flurbiprofen is more ulcerogenic than its (S)-enantiomer.
Topics: Animals; Digestive System; Female; Flurbiprofen; Gastrointestinal Diseases; Jejunum; Necrosis; Rats; | 1993 |
R-flurbiprofen chemoprevention and treatment of intestinal adenomas in the APC(Min)/+ mouse model: implications for prophylaxis and treatment of colon cancer.
Topics: Adenoma; Adenomatous Polyposis Coli; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-St | 1997 |
Mechanism of enhancement of intestinal ulcerogenicity of S-aryl propionic acids by their R-enantiomers in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship | 1998 |
Role of tumour necrosis factor-alpha and inducible nitric oxide synthase in the prevention of nitro-flurbiprofen small intestine toxicity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Flurbiprofen; Intestine, Small; Male; Nitric Oxide | 1998 |
Treatment and survival study in the C57BL/6J-APC(Min)/+(Min) mouse with R-flurbiprofen.
Topics: Adenomatous Polyposis Coli; Alleles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colon; Coloni | 2000 |
[A case of drug-induced esophageal ulcer developed at the esophageal constriction due to the right aortic arch].
Topics: Adult; Aorta, Thoracic; Esophageal Diseases; Esophageal Stenosis; Flurbiprofen; Humans; Male; Ulcer | 1992 |