Page last updated: 2024-10-27

flurbiprofen and Scleritis

flurbiprofen has been researched along with Scleritis in 4 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Scleritis: Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.

Research Excerpts

ExcerptRelevanceReference
"Retrospective chart review of 126 patients with non-necrotizing anterior scleritis treated with oral flurbiprofen (Froben®(Abbott Healthcare)) with (Group B, n = 61) or without (Group A, n = 65) topical steroids was performed and time to remission was plotted."7.83Flurbiprofen: A Nonselective Cyclooxygenase (COX) Inhibitor for Treatment of Noninfectious, Non-necrotizing Anterior Scleritis. ( Agrawal, R; Gonzalez-Lopez, JJ; Khan, S; Lee, CS; Pavesio, C; Rodrigues, V, 2016)
"Retrospective chart review of 126 patients with non-necrotizing anterior scleritis treated with oral flurbiprofen (Froben®(Abbott Healthcare)) with (Group B, n = 61) or without (Group A, n = 65) topical steroids was performed and time to remission was plotted."3.83Flurbiprofen: A Nonselective Cyclooxygenase (COX) Inhibitor for Treatment of Noninfectious, Non-necrotizing Anterior Scleritis. ( Agrawal, R; Gonzalez-Lopez, JJ; Khan, S; Lee, CS; Pavesio, C; Rodrigues, V, 2016)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agrawal, R1
Lee, CS1
Gonzalez-Lopez, JJ1
Khan, S1
Rodrigues, V1
Pavesio, C2
Cunningham, ET1
McCluskey, P1
Wakefield, D1
Zierhut, M1
Nessim, M1
Kyprianou, I1
Kumar, V1
Murray, PI1
Lyons, CJ1
Hakin, KN1
Watson, PG1

Trials

1 trial available for flurbiprofen and Scleritis

ArticleYear
Topical flurbiprofen: an effective treatment for episcleritis?
    Eye (London, England), 1990, Volume: 4 ( Pt 3)

    Topics: Administration, Topical; Adult; Aged; Double-Blind Method; Female; Flurbiprofen; Humans; Male; Middl

1990

Other Studies

3 other studies available for flurbiprofen and Scleritis

ArticleYear
Flurbiprofen: A Nonselective Cyclooxygenase (COX) Inhibitor for Treatment of Noninfectious, Non-necrotizing Anterior Scleritis.
    Ocular immunology and inflammation, 2016, Volume: 24, Issue:1

    Topics: Administration, Oral; Adult; Aged; Anterior Eye Segment; Cohort Studies; Cyclooxygenase Inhibitors;

2016
Scleritis.
    Ocular immunology and inflammation, 2016, Volume: 24, Issue:1

    Topics: Cyclooxygenase Inhibitors; Female; Flurbiprofen; Humans; Male; Middle Aged; Scleritis

2016
Anterior scleritis, scleral thinning, and intraocular pressure measurement.
    Ocular immunology and inflammation, 2005, Volume: 13, Issue:6

    Topics: Anti-Inflammatory Agents; Disease Progression; Drug Therapy, Combination; Female; Flurbiprofen; Huma

2005