flurbiprofen has been researched along with Pyrexia in 14 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The administration of flurbiprofen, a potent non-steroidal anti-inflammatory drug (NSAID), to goats infected with trypanosomes resulted in high elevated parasitaemia and suppression of fever." | 7.68 | Influence of fever and flurbiprofen on trypanosome growth. ( Brun, R; Dwinger, RH; Franssen, FF; Kooy, RF; Nieuwenhuijs, J; van Miert, AS; Zwart, D, 1990) |
| "Pretreatment with flurbiprofen partly antagonized the febrile reactions to r." | 5.29 | Effects of flurbiprofen on recombinant human IL-1 alpha-induced fever and associated clinical, haematological and blood biochemical changes in the dwarf goat. ( Van Duin, CT; Van Miert, AS; Wensing, T, 1994) |
| "Pretreatment with flurbiprofen completely abolished the febrile reactions to endotoxin." | 5.26 | Endotoxin-induced fever and associated haematological and blood biochemical changes in the goat: the effect of repeated administration and the influence of flurbiprofen. ( Schotman, AJ; van Duin, CT; van Miert, AS; Verheijden, JH, 1982) |
| "The administration of flurbiprofen, a potent non-steroidal anti-inflammatory drug (NSAID), to goats infected with trypanosomes resulted in high elevated parasitaemia and suppression of fever." | 3.68 | Influence of fever and flurbiprofen on trypanosome growth. ( Brun, R; Dwinger, RH; Franssen, FF; Kooy, RF; Nieuwenhuijs, J; van Miert, AS; Zwart, D, 1990) |
| "Flurbiprofen, like its predecessor ibuprofen, possesses antipyretic properties in the endotoxin-fevered rabbit." | 3.65 | The antipyretic effect of flurbiprofen. ( Van Duin, CT; Van Miert, AS, 1977) |
| " Plant-based therapeutic agents including essential oils in combination with low-dose synthetic drugs have been shown to produce synergistic effects and reduce complications of synthetic drugs." | 1.91 | Anti-inflammatory mechanisms of eucalyptol rich Eucalyptus globulus essential oil alone and in combination with flurbiprofen. ( Arooj, B; Asghar, S; Asif, M; Chohan, T; Khalid, SH; Khan, IU; Saleem, M; Yaseen, HS; Zubair, HM, 2023) |
| "Flurbiprofen axetil was used for slight postoperative fever." | 1.35 | [Perioperative anesthetic management of a patient with multiple sclerosis]. ( Hirose, M; Ishimoto, M; Matsuki, Y; Nobukawa, Y; Okada, A; Shigemi, K; Shimizu, K; Tabata, M; Tsugita, K; Ueda, M, 2009) |
| "Pretreatment with flurbiprofen partly antagonized the febrile reactions to r." | 1.29 | Effects of flurbiprofen on recombinant human IL-1 alpha-induced fever and associated clinical, haematological and blood biochemical changes in the dwarf goat. ( Van Duin, CT; Van Miert, AS; Wensing, T, 1994) |
| "Pretreatment with flurbiprofen completely abolished the febrile reactions to endotoxin." | 1.26 | Endotoxin-induced fever and associated haematological and blood biochemical changes in the goat: the effect of repeated administration and the influence of flurbiprofen. ( Schotman, AJ; van Duin, CT; van Miert, AS; Verheijden, JH, 1982) |
| " The very shallow dose-response curves for flurbiprofen compared with acetylsalicylic acid, especially in the mouse and the rat test systems, are not due to an unreliable or abnormal absorption, which suggests that in these species the mode of action of flurbiprofen is not identical with that of acetylsalicylic acid." | 1.25 | Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent. ( Adams, SS; McCullough, KF; Nicholson, JS, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Arooj, B | 1 |
| Asghar, S | 1 |
| Saleem, M | 1 |
| Khalid, SH | 1 |
| Asif, M | 1 |
| Chohan, T | 1 |
| Khan, IU | 1 |
| Zubair, HM | 1 |
| Yaseen, HS | 1 |
| Okada, A | 1 |
| Hirose, M | 1 |
| Shimizu, K | 1 |
| Tsugita, K | 1 |
| Matsuki, Y | 1 |
| Nobukawa, Y | 1 |
| Tabata, M | 1 |
| Ishimoto, M | 1 |
| Ueda, M | 1 |
| Shigemi, K | 1 |
| van Miert, AS | 5 |
| van Duin, CT | 4 |
| Verheijden, JH | 1 |
| Schotman, AJ | 1 |
| Wensing, T | 1 |
| Harris, TG | 1 |
| Battaglia, DF | 1 |
| Brown, ME | 1 |
| Brown, MB | 1 |
| Carlson, NE | 1 |
| Viguié, C | 1 |
| Williams, CY | 1 |
| Karsch, FJ | 1 |
| Tay, CH | 1 |
| Leong, SF | 1 |
| Adams, SS | 1 |
| McCullough, KF | 1 |
| Nicholson, JS | 1 |
| Massart-Leën, AM | 1 |
| Burvenich, C | 1 |
| Vandeputte-Van Messom, G | 1 |
| Hilderson, H | 1 |
| Cooper, AL | 1 |
| Rothwell, NJ | 2 |
| Busbridge, NJ | 1 |
| Lefeuvre, RA | 1 |
| Hardwick, AJ | 1 |
| Gauldie, J | 1 |
| Hopkins, SJ | 1 |
| Zwart, D | 1 |
| Brun, R | 1 |
| Dwinger, RH | 1 |
| Franssen, FF | 1 |
| Nieuwenhuijs, J | 1 |
| Kooy, RF | 1 |
| Troullos, ES | 1 |
| Hargreaves, KM | 1 |
| Butler, DP | 1 |
| Dionne, RA | 1 |
| Anika, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Postoperative Edema and Pain Following Third Molar Extraction With Application of Pulsed Electromagnetic Field (PEMF) Therapy[NCT02376946] | 49 participants (Actual) | Interventional | 2014-01-31 | Terminated (stopped due to Sponsor decision) | |||
| Efficacy of Steroids on Functional Outcomes After Musculoskeletal Injuries of the Hand[NCT05003596] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for flurbiprofen and Pyrexia
| Article | Year |
|---|---|
Antipyretic activity of flurbiprofen.
Topics: Adolescent; Adult; Aspirin; Child; Clinical Trials as Topic; Female; Fever; Flurbiprofen; Humans; Ma | 1977 |
Comparison of nonsteroidal anti-inflammatory drugs, ibuprofen and flurbiprofen, with methylprednisolone and placebo for acute pain, swelling, and trismus.
Topics: Adult; Double-Blind Method; Evaluation Studies as Topic; Female; Fever; Flurbiprofen; Humans; Ibupro | 1990 |
Comparison of nonsteroidal anti-inflammatory drugs, ibuprofen and flurbiprofen, with methylprednisolone and placebo for acute pain, swelling, and trismus.
Topics: Adult; Double-Blind Method; Evaluation Studies as Topic; Female; Fever; Flurbiprofen; Humans; Ibupro | 1990 |
Comparison of nonsteroidal anti-inflammatory drugs, ibuprofen and flurbiprofen, with methylprednisolone and placebo for acute pain, swelling, and trismus.
Topics: Adult; Double-Blind Method; Evaluation Studies as Topic; Female; Fever; Flurbiprofen; Humans; Ibupro | 1990 |
Comparison of nonsteroidal anti-inflammatory drugs, ibuprofen and flurbiprofen, with methylprednisolone and placebo for acute pain, swelling, and trismus.
Topics: Adult; Double-Blind Method; Evaluation Studies as Topic; Female; Fever; Flurbiprofen; Humans; Ibupro | 1990 |
12 other studies available for flurbiprofen and Pyrexia
| Article | Year |
|---|---|
Anti-inflammatory mechanisms of eucalyptol rich Eucalyptus globulus essential oil alone and in combination with flurbiprofen.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; E | 2023 |
[Perioperative anesthetic management of a patient with multiple sclerosis].
Topics: Adult; Anesthesia, Epidural; Fentanyl; Fever; Flurbiprofen; Humans; Infusions, Intravenous; Laparosc | 2009 |
Endotoxin-induced fever and associated haematological and blood biochemical changes in the goat: the effect of repeated administration and the influence of flurbiprofen.
Topics: Animals; Blood Chemical Analysis; Body Temperature; Drug Tolerance; Escherichia coli; Female; Fever; | 1982 |
Effects of flurbiprofen on recombinant human IL-1 alpha-induced fever and associated clinical, haematological and blood biochemical changes in the dwarf goat.
Topics: Animals; Blood Glucose; Body Temperature; Female; Fever; Flurbiprofen; Gastrointestinal Motility; Go | 1994 |
Prostaglandins mediate the endotoxin-induced suppression of pulsatile gonadotropin-releasing hormone and luteinizing hormone secretion in the ewe.
Topics: Animals; Depression, Chemical; Endotoxins; Escherichia coli; Female; Fever; Flurbiprofen; Gonadotrop | 2000 |
The antipyretic effect of flurbiprofen.
Topics: Analgesics; Animals; Depression, Chemical; Escherichia coli; Fever; Flurbiprofen; Goats; Leukocytes; | 1977 |
Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Cap | 1975 |
Partial prostaglandin-mediated mechanism controlling the release of cortisol in plasma after intravenous administration of endotoxins.
Topics: Animals; Disease Models, Animal; Female; Fever; Flurbiprofen; Goat Diseases; Goats; Hydrocortisone; | 1992 |
Mechanisms of early and late hypermetabolism and fever after localized tissue injury in rats.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Antibodies; Capsaicin; Central Nervous S | 1991 |
Interleukin-6 is a centrally acting endogenous pyrogen in the rat.
Topics: Animals; Body Temperature; Fever; Flurbiprofen; Interleukin-6; Male; Oxygen Consumption; Pyrogens; R | 1991 |
Influence of fever and flurbiprofen on trypanosome growth.
Topics: Animals; Body Temperature; Female; Fever; Flurbiprofen; Goat Diseases; Goats; Rats; Rats, Inbred Str | 1990 |
Anorexia during febrile conditions in dwarf goats. The effect of diazepam, flurbiprofen and naloxone.
Topics: Animals; Anorexia; Diazepam; Drug Therapy, Combination; Eating; Ehrlichia; Endotoxins; Escherichia c | 1986 |