flurbiprofen has been researched along with Polyarthritis in 16 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flurbiprofen has been compared with phenylbutazone in a double-blind study involving 33 patients with acute gout." | 9.05 | Double-blind trial of flurbiprofen and phenylbutazone in acute gouty arthritis. ( Butler, RC; Goddard, DH; Higgens, CS; Hollingworth, P; Pease, CT; Scott, JT; Stodell, MA, 1985) |
| "The potential antinociceptive effects of the S(+)- and R(-)-enantiomers of flurbiprofen (SFB and RFB, respectively) were investigated when given intravenously to rats using the pain-induced functional impairment model in the rat (PIFIR), an animal model of arthritic pain." | 7.70 | Analysis of antinociceptive effects of flurbiprofen enantiomers in a rat model of arthritic pain. ( Cabré, F; Díaz, MI; Domínguez, AM; García, ML; Hernández, GP; López-Muñoz, FJ; Mauleón, D; Ventura, R, 2000) |
| "The relative efficacy and safety of flurbiprofen (Ansaid, Upjohn) and indomethacin were compared in 29 patients with monoarticular gouty arthritis of less than 48 hours' duration." | 7.67 | Flurbiprofen in the treatment of acute gout. A comparison with indomethacin. ( Brinn, EL; Lamborn, KR; Lomen, PL; Sack, RL; Turner, LF; Winblad, MA, 1986) |
| "Twenty-seven patients with inflammatory and degenerative arthritis, who had been treated with either ketoprofen and flurbiprofen, for a period of up to twenty-four months, were examined for evidence of ocular toxicity." | 7.65 | Ophthalmic screening of patients receiving ketoprofen or flurbiprofen medication for inflammatory and degenerative joint diseases. ( Mushin, A; Williams, H; Zutshi, D, 1976) |
| "Flurbiprofen has been compared with phenylbutazone in a double-blind study involving 33 patients with acute gout." | 5.05 | Double-blind trial of flurbiprofen and phenylbutazone in acute gouty arthritis. ( Butler, RC; Goddard, DH; Higgens, CS; Hollingworth, P; Pease, CT; Scott, JT; Stodell, MA, 1985) |
| "Nitroflurbiprofen is a nitrosylated flurbiprofen analog under development by NicOx for the potential treatment of urinary incontinence, Alzheimer's disease (AD) and the prevention and treatment of accelerated bone resorption associated with disorders such as osteoporosis, inflammatory joint disease and Paget's disease." | 4.82 | Nitroflurbiprofen (NicOx). ( Scatena, R, 2004) |
| "Flurbiprofen (FLB) is one of the phenylalkanoic acid derivatives of non-steroidal anti-inflammatory drugs used for the management of pain and inflammation in patients with arthritis." | 3.80 | Simultaneous determination of flurbiprofen and its hydroxy metabolite in human plasma by liquid chromatography-tandem mass spectrometry for clinical application. ( Byeon, JY; Choi, CI; Jang, CG; Kim, SH; Kim, YH; Lee, HI; Lee, JE; Lee, SY; Lee, YJ; Park, SY, 2014) |
| "The potential antinociceptive effects of the S(+)- and R(-)-enantiomers of flurbiprofen (SFB and RFB, respectively) were investigated when given intravenously to rats using the pain-induced functional impairment model in the rat (PIFIR), an animal model of arthritic pain." | 3.70 | Analysis of antinociceptive effects of flurbiprofen enantiomers in a rat model of arthritic pain. ( Cabré, F; Díaz, MI; Domínguez, AM; García, ML; Hernández, GP; López-Muñoz, FJ; Mauleón, D; Ventura, R, 2000) |
| "The relative efficacy and safety of flurbiprofen (Ansaid, Upjohn) and indomethacin were compared in 29 patients with monoarticular gouty arthritis of less than 48 hours' duration." | 3.67 | Flurbiprofen in the treatment of acute gout. A comparison with indomethacin. ( Brinn, EL; Lamborn, KR; Lomen, PL; Sack, RL; Turner, LF; Winblad, MA, 1986) |
| "Twenty-seven patients with inflammatory and degenerative arthritis, who had been treated with either ketoprofen and flurbiprofen, for a period of up to twenty-four months, were examined for evidence of ocular toxicity." | 3.65 | Ophthalmic screening of patients receiving ketoprofen or flurbiprofen medication for inflammatory and degenerative joint diseases. ( Mushin, A; Williams, H; Zutshi, D, 1976) |
| "Improvement of patients in all groups reached statistical significance after 1 month's treatment and remained significant at 12 months." | 2.66 | A long-term study of flurbiprofen in rheumatological disorders: III. Other articular conditions. ( Busson, M, 1986) |
| " Plant-based therapeutic agents including essential oils in combination with low-dose synthetic drugs have been shown to produce synergistic effects and reduce complications of synthetic drugs." | 1.91 | Anti-inflammatory mechanisms of eucalyptol rich Eucalyptus globulus essential oil alone and in combination with flurbiprofen. ( Arooj, B; Asghar, S; Asif, M; Chohan, T; Khalid, SH; Khan, IU; Saleem, M; Yaseen, HS; Zubair, HM, 2023) |
| "Flurbiprofen has been shown to be effective in relieving symptoms in the degenerative and inflammatory arthritides and side-effects have not proved a problem." | 1.26 | A long-term assessment of flurbiprofen. ( Marsh, BD; Sheldrake, FE; Webber, JM, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (62.50) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Arooj, B | 1 |
| Asghar, S | 1 |
| Saleem, M | 1 |
| Khalid, SH | 1 |
| Asif, M | 1 |
| Chohan, T | 1 |
| Khan, IU | 1 |
| Zubair, HM | 1 |
| Yaseen, HS | 1 |
| Lee, HI | 1 |
| Choi, CI | 1 |
| Byeon, JY | 1 |
| Lee, JE | 1 |
| Park, SY | 1 |
| Kim, YH | 1 |
| Kim, SH | 1 |
| Lee, YJ | 1 |
| Jang, CG | 1 |
| Lee, SY | 1 |
| Scatena, R | 1 |
| Teixeira, AV | 1 |
| Poças, L | 1 |
| Serrão, D | 1 |
| Schaible, HG | 1 |
| Neugebauer, V | 1 |
| Geisslinger, G | 1 |
| Beck, U | 1 |
| Karateev, DE | 1 |
| Nasonova, VA | 1 |
| Ivanova, MM | 1 |
| López-Muñoz, FJ | 1 |
| Ventura, R | 1 |
| Díaz, MI | 1 |
| Hernández, GP | 1 |
| Domínguez, AM | 1 |
| García, ML | 1 |
| Cabré, F | 1 |
| Mauleón, D | 1 |
| Sheldrake, FE | 1 |
| Webber, JM | 1 |
| Marsh, BD | 1 |
| Williams, H | 1 |
| Zutshi, D | 1 |
| Mushin, A | 1 |
| Goldberg, RL | 1 |
| Rubin, AS | 1 |
| Anderson, M | 1 |
| Bedi, SS | 1 |
| Boston, PF | 2 |
| Cardoe, N | 1 |
| Glick, EN | 1 |
| Khan, AU | 1 |
| Littler, TR | 1 |
| Constad, D | 1 |
| Busson, M | 1 |
| Hunneyball, IM | 1 |
| Crossley, MJ | 1 |
| Spowage, M | 1 |
| Butler, RC | 1 |
| Goddard, DH | 1 |
| Higgens, CS | 1 |
| Hollingworth, P | 1 |
| Pease, CT | 1 |
| Stodell, MA | 1 |
| Scott, JT | 1 |
| Lomen, PL | 1 |
| Turner, LF | 1 |
| Lamborn, KR | 1 |
| Winblad, MA | 1 |
| Sack, RL | 1 |
| Brinn, EL | 1 |
2 reviews available for flurbiprofen and Polyarthritis
| Article | Year |
|---|---|
Nitroflurbiprofen (NicOx).
Topics: Alzheimer Disease; Animals; Arthritis; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Flurbipr | 2004 |
[Flurbiprofen: pharmacological characteristics and clinical effectiveness].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Flurbiprofen; Humans; | 1998 |
2 trials available for flurbiprofen and Polyarthritis
| Article | Year |
|---|---|
A long-term study of flurbiprofen in rheumatological disorders: III. Other articular conditions.
Topics: Adolescent; Adult; Aged; Arthritis; Child; Clinical Trials as Topic; Drug Therapy, Combination; Fema | 1986 |
Double-blind trial of flurbiprofen and phenylbutazone in acute gouty arthritis.
Topics: Adult; Aged; Arthritis; Clinical Trials as Topic; Double-Blind Method; Flurbiprofen; Gout; Humans; M | 1985 |
12 other studies available for flurbiprofen and Polyarthritis
| Article | Year |
|---|---|
Anti-inflammatory mechanisms of eucalyptol rich Eucalyptus globulus essential oil alone and in combination with flurbiprofen.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; E | 2023 |
Simultaneous determination of flurbiprofen and its hydroxy metabolite in human plasma by liquid chromatography-tandem mass spectrometry for clinical application.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Chromatography, High Pressure Liquid; Flurbiprof | 2014 |
Study of the gastric mucosa in rheumatic patients before and after the administration of flurbiprofen.
Topics: Adult; Arthritis; Female; Flurbiprofen; Gastric Mucosa; Humans; Male; Middle Aged; Propionates | 1981 |
The effects of S- and R-flurbiprofen on the inflammation-evoked intraspinal release of immunoreactive substance P--a study with antibody microprobes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Flurbiprofen; Immunologic Techniques; K | 1998 |
Analysis of antinociceptive effects of flurbiprofen enantiomers in a rat model of arthritic pain.
Topics: Analgesics; Animals; Area Under Curve; Arthritis; Disease Models, Animal; Dose-Response Relationship | 2000 |
A long-term assessment of flurbiprofen.
Topics: Arthritis; Arthritis, Rheumatoid; Bone Diseases; Female; Flurbiprofen; Humans; Joint Diseases; Male; | 1977 |
Ophthalmic screening of patients receiving ketoprofen or flurbiprofen medication for inflammatory and degenerative joint diseases.
Topics: Adult; Aged; Analgesics; Arthritis; Benzophenones; Cornea; Eye; Female; Flurbiprofen; Follow-Up Stud | 1976 |
Serum hyaluronate as a marker for disease severity in the Lactobacillus casei model of arthritis in the rat.
Topics: Animals; Arthritis; Arthritis, Experimental; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; | 1989 |
A long-term study of flurbiprofen sustained-release.
Topics: Adult; Aged; Aged, 80 and over; Arthritis; Delayed-Action Preparations; Female; Flurbiprofen; Follow | 1988 |
A general practice study of flurbiprofen sustained-release.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis; Delayed-Action Preparations; Female; Flurbipr | 1988 |
Pharmacological studies of antigen-induced arthritis in BALB/c mice. I. Characterization of the arthritis and the effects of steroidal and non-steroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Dexamethasone; Female; Flurbi | 1986 |
Flurbiprofen in the treatment of acute gout. A comparison with indomethacin.
Topics: Acute Disease; Arthritis; Drug Evaluation; Flurbiprofen; Gout; Humans; Indomethacin; Pain; Propionat | 1986 |