flurbiprofen has been researched along with Periodontal Diseases in 19 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
Periodontal Diseases: Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flurbiprofen-treated patients however, demonstrated a significantly greater proportion of sites (8." | 2.67 | The use of topical flurbiprofen as an adjunct to non-surgical management of periodontal disease. ( Aitken, D; Benn, DK; Heasman, PA; Kelly, PJ; Seymour, RA, 1993) |
| "Flurbiprofen was shown to possess an adequate analgesic effect superior to either placebo (P less than 0." | 2.67 | Analgesic efficacy of flurbiprofen as compared to acetaminophen and placebo after periodontal surgery. ( Gallardo, F; Rossi, E, 1990) |
| " For preliminary dose-response studies, antibiotic sensitivity blank disks loaded with 10 microliters of flurbiprofen 250 micrograms, 50 micrograms and 5 micrograms, or ibuprofen 500 micrograms, 50 micrograms and 5 micrograms were placed on the seeded agar plates." | 1.28 | Antimicrobial activity of flurbiprofen and ibuprofen in vitro against six common periodontal pathogens. ( Fleury, AA; Hammond, BF; Hersh, EV, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (68.42) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Williams, RC | 10 |
| Jeffcoat, MK | 8 |
| Wechter, WJ | 5 |
| Johnson, HG | 5 |
| Kaplan, ML | 5 |
| Goldhaber, P | 7 |
| ElAttar, TM | 1 |
| Lin, HS | 1 |
| Tira, DE | 1 |
| Hoshikawa, M | 1 |
| Seki, T | 1 |
| Hayashi, T | 1 |
| Akiyama, A | 1 |
| Nakamura, Y | 1 |
| Kamiyama, Y | 1 |
| Takahashi, Y | 1 |
| Hagiwara, H | 1 |
| Horiuchi, H | 1 |
| Tokusu, S | 1 |
| Heasman, PA | 1 |
| Benn, DK | 1 |
| Kelly, PJ | 1 |
| Seymour, RA | 1 |
| Aitken, D | 1 |
| Howell, TH | 4 |
| Paquette, DW | 1 |
| Ishikawa, T | 1 |
| Ono, M | 1 |
| Ogushi, T | 1 |
| Hersh, EV | 1 |
| Hammond, BF | 1 |
| Fleury, AA | 1 |
| Gallardo, F | 1 |
| Rossi, E | 1 |
| Gandrup, JS | 1 |
| Hall, CM | 2 |
| Offenbacher, S | 1 |
| Ciancio, SC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Use of Non-Steroidal Anti-Inflammatory Drugs as a Tool of Positive Change in Peri-Implants Mucositis Microbiome[NCT03090009] | Early Phase 1 | 100 participants (Anticipated) | Interventional | 2017-04-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for flurbiprofen and Periodontal Diseases
| Article | Year |
|---|---|
Nonsteroidal antiinflammatory drugs as inhibitors of periodontal disease progression.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Resorption; Flurbiprofen; | 1993 |
Modulation of host inflammatory mediators as a treatment strategy for periodontal diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Cyclooxygenase 2; Cyclooxygenas | 2000 |
Chemotherapeutic agents as adjuncts in the treatment of periodontal disease.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Antimetabolites; Flurbiprofen; Humans; Metronid | 1991 |
Chemotherapeutic agents and periodontal therapy. Their impact on clinical practice.
Topics: Administration, Topical; Anti-Bacterial Agents; Cetylpyridinium; Chlorhexidine; Dental Plaque; Denti | 1986 |
3 trials available for flurbiprofen and Periodontal Diseases
| Article | Year |
|---|---|
[Effects of flurbiprofen (FP-70) on pain in periodontics: double-blind methods in comparison with aspirin].
Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofe | 1980 |
The use of topical flurbiprofen as an adjunct to non-surgical management of periodontal disease.
Topics: Administration, Topical; Adult; Analysis of Variance; Bone Regeneration; Dental Plaque Index; Double | 1993 |
Analgesic efficacy of flurbiprofen as compared to acetaminophen and placebo after periodontal surgery.
Topics: Acetaminophen; Adult; Double-Blind Method; Female; Flurbiprofen; Humans; Male; Middle Aged; Pain Mea | 1990 |
12 other studies available for flurbiprofen and Periodontal Diseases
| Article | Year |
|---|---|
Non-steroidal anti-inflammatory drug treatment of periodontitis in beagles.
Topics: Alveolar Process; Animals; Bone Resorption; Dogs; Female; Flurbiprofen; Periodontal Diseases; Propio | 1984 |
Arachidonic acid metabolism in inflamed gingiva and its inhibition by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arachidonic Acids; Flurbiprofen; Gingivitis; Humans; Periodontal Diseases; | 1984 |
[Clinical results of froben granules in conservative dentistry].
Topics: Adolescent; Adult; Aged; Dosage Forms; Female; Flurbiprofen; Humans; Male; Middle Aged; Periodontal | 1981 |
[Clinical use of a flurbiprofen preparation (Froben) for various pains in operative dentistry].
Topics: Adolescent; Adult; Aged; Female; Flurbiprofen; Humans; Male; Middle Aged; Pain, Postoperative; Perio | 1979 |
Antimicrobial activity of flurbiprofen and ibuprofen in vitro against six common periodontal pathogens.
Topics: Aggregatibacter actinomycetemcomitans; Bacteroides; Eikenella corrodens; Flurbiprofen; Fusobacterium | 1991 |
Flurbiprofen treatment of periodontal disease in beagles.
Topics: Animals; Bone Resorption; Dogs; Flurbiprofen; Periodontal Diseases; Periodontal Index; Propionates; | 1986 |
Indomethacin or flurbiprofen treatment of periodontitis in beagles: comparison of effect on bone loss.
Topics: Alveolar Process; Animals; Bone Resorption; Dogs; Female; Flurbiprofen; Indomethacin; Periodontal Di | 1987 |
Indomethacin or flurbiprofen treatment of periodontitis in beagles: effect on crevicular fluid arachidonic acid metabolites compared with effect on alveolar bone loss.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bone Resorption; Cyclooxygenase Inhibitors; Dogs; Fema | 1988 |
Treating periodontal disease.
Topics: Alveolar Process; Animals; Bone Resorption; Dogs; Flurbiprofen; Periodontal Diseases; Propionates | 1986 |
Nuclear medicine techniques for the detection of active alveolar bone loss.
Topics: Alveolar Process; Animals; Bone Resorption; Diet; Dogs; Female; Flurbiprofen; Humans; Male; Periodon | 1987 |
Nuclear medicine. An indicator of "active" alveolar bone loss in beagle dogs treated with nonsteroidal anti-inflammatory drug.
Topics: Alveolar Process; Animals; Bone Resorption; Dental Scaling; Dogs; Flurbiprofen; Periodontal Diseases | 1985 |
Flurbiprofen: a potent inhibitor of alveolar bone resorption in beagles.
Topics: Alveolar Process; Animals; Bone Resorption; Dogs; Female; Flurbiprofen; Humans; Periodontal Diseases | 1985 |