flurbiprofen has been researched along with Peptic Ulcer in 3 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flurbiprofen-treated rats showed severe gastrointestinal ulcerations (bleeding in 3/8 rats) and nefrotoxicity, which was not observed in nitroflurbiprofen-treated cirrhotic rats." | 1.34 | Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portal hypertension in rats. ( Fevery, J; Laleman, W; Nevens, F; Van der Elst, I; Van Landeghem, L; Zeegers, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laleman, W | 1 |
| Van Landeghem, L | 1 |
| Van der Elst, I | 1 |
| Zeegers, M | 1 |
| Fevery, J | 1 |
| Nevens, F | 1 |
| McCracken, JD | 1 |
| Wechter, WJ | 1 |
| Liu, Y | 1 |
| Chase, RL | 1 |
| Kantoci, D | 1 |
| Murray, ED | 1 |
| Quiggle, DD | 1 |
| Mineyama, Y | 1 |
| Mahmud, T | 1 |
| Somasundaram, S | 1 |
| Sigthorsson, G | 1 |
| Simpson, RJ | 1 |
| Rafi, S | 1 |
| Foster, R | 1 |
| Tavares, IA | 1 |
| Roseth, A | 1 |
| Hutt, AJ | 1 |
| Jacob, M | 1 |
| Pacy, J | 1 |
| Scott, DL | 1 |
| Wrigglesworth, JM | 1 |
| Bjarnason, I | 1 |
3 other studies available for flurbiprofen and Peptic Ulcer
| Article | Year |
|---|---|
Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portal hypertension in rats.
Topics: Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Endoth | 2007 |
Antiproliferative effects of the enantiomers of flurbiprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cyclooxygenase Inhibitors; Female; | 1996 |
Enantiomers of flurbiprofen can distinguish key pathophysiological steps of NSAID enteropathy in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Blood Proteins; Cyclooxygenase Inhibit | 1998 |