flurbiprofen has been researched along with Osteoarthritis, Knee in 7 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Non-inferiority of SFPP to diclofenac gel was demonstrated in the efficacy for pain on rising from a chair." | 5.51 | Efficacy and safety of S-flurbiprofen plaster in knee osteoarthritis patients: A 2-week randomized controlled Phase III clinical trial compared to diclofenac gel. ( Fuady, A; Matsumoto, H; Tomatsu, K; Yasuda, S, 2022) |
| " There were four secondary outcomes, including the extent of pain relief, the change trends of VAS scores, joint function scores measured by the Western Ontario and McMaster University Osteoarthritis Index (WOMAC), and adverse events." | 3.30 | Efficacy and safety of flurbiprofen cataplasms versus loxoprofen sodium cataplasms in knee osteoarthritis: a randomized controlled trial. ( Cheng, Y; Guan, Z; Jia, J; Kan, J; Li, D; Liu, J; Wang, Z; Wu, Z; Xue, T; Yuan, P; Zhai, S; Zhang, G; Zhang, H; Zhang, K, 2023) |
| " Cmax and AUC0-∞ were dose-proportional." | 2.82 | Plasma pharmacokinetics and synovial concentrations of S-flurbiprofen plaster in humans. ( Hoshino, Y; Kamezawa, M; Matsumoto, H; Matsushita, I; Otsuka, N; Sasaki, S; Uebaba, K; Yamada, I; Yataba, I, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Amemiya, M | 1 |
| Nakagawa, Y | 1 |
| Yoshimura, H | 1 |
| Takahashi, T | 1 |
| Inomata, K | 1 |
| Nagase, T | 1 |
| Ju, YJ | 1 |
| Shimaya, M | 1 |
| Tsukada, S | 1 |
| Hirasawa, N | 1 |
| Koga, H | 1 |
| Tomatsu, K | 1 |
| Yasuda, S | 1 |
| Fuady, A | 1 |
| Matsumoto, H | 3 |
| Lin, T | 1 |
| Liu, Z | 1 |
| Ji, W | 1 |
| Zhang, P | 1 |
| Li, D | 1 |
| Cheng, Y | 1 |
| Yuan, P | 1 |
| Wu, Z | 1 |
| Liu, J | 1 |
| Kan, J | 1 |
| Zhang, K | 1 |
| Wang, Z | 1 |
| Zhang, H | 1 |
| Zhang, G | 1 |
| Xue, T | 1 |
| Jia, J | 1 |
| Zhai, S | 1 |
| Guan, Z | 1 |
| Yataba, I | 2 |
| Otsuka, N | 2 |
| Matsushita, I | 2 |
| Kamezawa, M | 1 |
| Yamada, I | 1 |
| Sasaki, S | 1 |
| Uebaba, K | 1 |
| Hoshino, Y | 2 |
| Uzun, H | 1 |
| Tuzun, S | 1 |
| Ozaras, N | 1 |
| Aydin, S | 1 |
| Ozaras, R | 1 |
| Dondurmaci, S | 1 |
| Tuzun, F | 1 |
6 trials available for flurbiprofen and Osteoarthritis, Knee
| Article | Year |
|---|---|
Comparison of tissue pharmacokinetics of esflurbiprofen plaster with flurbiprofen tablets in patients with knee osteoarthritis: A multicenter randomized controlled trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Flurbiprofen; Humans; Osteoarthritis, Knee; Prospective Stu | 2021 |
Efficacy and safety of S-flurbiprofen plaster in knee osteoarthritis patients: A 2-week randomized controlled Phase III clinical trial compared to diclofenac gel.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Flurbiprofen; Humans; Oste | 2022 |
Efficacy and safety of flurbiprofen cataplasms versus loxoprofen sodium cataplasms in knee osteoarthritis: a randomized controlled trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Flurbiprofen; Humans; Mi | 2023 |
Plasma pharmacokinetics and synovial concentrations of S-flurbiprofen plaster in humans.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Fe | 2016 |
Efficacy of S-flurbiprofen plaster in knee osteoarthritis treatment: Results from a phase III, randomized, active-controlled, adequate, and well-controlled trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Fe | 2017 |
The effect of flurbiprofen and tiaprofenic acid on serum cytokine levels of patients with osteoarthrosis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Female; Flurbiprofen; Humans; Inter | 2001 |
1 other study available for flurbiprofen and Osteoarthritis, Knee
| Article | Year |
|---|---|
Effects of Knee Debridement with Flurbiprofen on Knee Function, Inflammatory Levels, and Bone Metabolism Activity in Patients with Knee Osteoarthritis.
Topics: Debridement; Flurbiprofen; Humans; Insulin-Like Growth Factor I; Osteoarthritis, Knee; Retrospective | 2022 |