Page last updated: 2024-10-27

flurbiprofen and Necrosis

flurbiprofen has been researched along with Necrosis in 7 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"The purposes of this investigation were (1) to develop an in vivo method of determining the myocardium at risk after experimental coronary occlusion; (2) to define the spatial geometry of the salvageable ischemic border zone; an (3) to assess the ability of flurbiprofen, an antiinflammatory agent, to protect ischemic myocardium from necrosis."3.66Demonstration of lateral and epicardial border zone salvage by flurbiprofen using an in vivo method for assessing myocardium at risk. ( Braunwald, E; Darsee, JR; Kloner, RA, 1981)
"In flurbiprofen-treated dogs regional function returned to normal within 5 min of reperfusion in both the subendocardium (%SS preocclusion = 17."1.26Early recovery of regional performance in salvaged ischemic myocardium following coronary artery occlusion in the dog. ( Braunwald, E; Darsee, JR; Kloner, RA, 1981)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Porrini, V1
Sarnico, I1
Benarese, M1
Branca, C1
Mota, M1
Lanzillotta, A1
Bellucci, A1
Parrella, E1
Faggi, L1
Spano, P1
Imbimbo, BP1
Pizzi, M1
Darsee, JR4
Kloner, RA4
Braunwald, E3
DeBoer, LW1
Glogar, DH1
Ertl, G1
Ingwall, JS1
Wechter, WJ1
Bigornia, AE1
Murray, ED1
Levine, BH1
Young, JW1
Yellon, DM1
Maxwell, MP1
Hearse, DJ1
Yoshida, S1
Eddy, L1
Downey, JM1

Other Studies

7 other studies available for flurbiprofen and Necrosis

ArticleYear
Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation.
    International journal of molecular sciences, 2017, Jan-18, Volume: 18, Issue:1

    Topics: Animals; Apoptosis; Caspase 3; Cell Nucleus; Cerebral Cortex; Cyclopropanes; Cytochromes c; Enzyme A

2017
Demonstration of lateral and epicardial border zone salvage by flurbiprofen using an in vivo method for assessing myocardium at risk.
    Circulation, 1981, Volume: 63, Issue:1

    Topics: Animals; Arterial Occlusive Diseases; Coronary Disease; Coronary Vessels; Dogs; Female; Flurbiprofen

1981
Early recovery of regional performance in salvaged ischemic myocardium following coronary artery occlusion in the dog.
    The Journal of clinical investigation, 1981, Volume: 68, Issue:1

    Topics: Animals; Blood Flow Velocity; Coronary Disease; Dogs; Female; Flurbiprofen; Heart; Male; Necrosis; P

1981
Observations on the experimental reduction of infarct size and on the delayed consequences of transient myocardial ischemia.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 651

    Topics: Animals; Captopril; Dogs; Fluorocarbons; Flurbiprofen; Myocardial Infarction; Myocardium; Necrosis;

1981
Dependency of location of salvageable myocardium on type of intervention.
    The American journal of cardiology, 1981, Volume: 48, Issue:4

    Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Flurbiprofen; Glycine; Heart; Ibuprof

1981
Rac-flurbiprofen is more ulcerogenic than its (S)-enantiomer.
    Chirality, 1993, Volume: 5, Issue:7

    Topics: Animals; Digestive System; Female; Flurbiprofen; Gastrointestinal Diseases; Jejunum; Necrosis; Rats;

1993
Infarct-size limitation--real or artifactual. Studies with flurbiprofen using a reperfusion model.
    Advances in myocardiology, 1985, Volume: 6

    Topics: Animals; Coronary Circulation; Dogs; Female; Flurbiprofen; Hemodynamics; Male; Myocardial Infarction

1985