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flurbiprofen and Muscle Contraction

flurbiprofen has been researched along with Muscle Contraction in 21 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"We examined the effects of U50,488, a kappa-opioid receptor agonist, and flurbiprofen axetil, a nonsteroidal antiinflammatory drug, in a visceral pain model using conscious rats."7.75The individual and combined effects of U50,488, and flurbiprofen axetil on visceral pain in conscious rats. ( Kitamura, T; Ogawa, M; Yamada, Y, 2009)
"We examined the effects of U50,488, a kappa-opioid receptor agonist, and flurbiprofen axetil, a nonsteroidal antiinflammatory drug, in a visceral pain model using conscious rats."3.75The individual and combined effects of U50,488, and flurbiprofen axetil on visceral pain in conscious rats. ( Kitamura, T; Ogawa, M; Yamada, Y, 2009)
"In patients with Duchenne muscular dystrophy (DMD) and the standard mdx mouse model of DMD, dystrophin deficiency causes loss of neuronal nitric oxide synthase (nNOSμ) from the sarcolemma, producing functional ischemia when the muscles are exercised."1.38Treatment with a nitric oxide-donating NSAID alleviates functional muscle ischemia in the mouse model of Duchenne muscular dystrophy. ( De Nardi, C; Monopoli, A; Ongini, E; Thomas, GD; Victor, RG; Ye, J, 2012)
"Treatment with flunixin meglumine or flurbiprofen almost completely abolished the febrile response during the first nine hours after infection, and the decrease in rumen motility was less pronounced in the treated animals."1.28Flunixin meglumine and flurbiprofen in cows with experimental Escherichia coli mastitis. ( Brand, A; Lohuis, JA; Van Leeuwen, W; Van Miert, AS; Verheijden, JH, 1989)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199011 (52.38)18.7374
1990's4 (19.05)18.2507
2000's5 (23.81)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kitamura, T1
Ogawa, M1
Yamada, Y1
Thomas, GD1
Ye, J1
De Nardi, C1
Monopoli, A1
Ongini, E1
Victor, RG1
Ates, M1
Hamza, M1
Seidel, K1
Kotalla, CE1
Ledent, C1
Gühring, H1
Wang, A1
Nishihashi, T1
Murakami, S1
Trandafir, CC1
Ji, X1
Shimizu, Y1
Kurahashi, K1
Nangle, MR1
Cotter, MA1
Cameron, NE1
Raeburn, D1
Rodger, IW1
Kester, M1
Ledvora, RF1
Bárány, M1
Mishra, DK1
Fridén, J1
Schmitz, MC1
Lieber, RL1
Kurata, R1
Takayanagi, I3
Hisayama, T3
Graham, J1
Awe, SO1
LeDay, AM1
Rice, JC1
Ramos, G1
Harris, LC1
Opere, CA1
Ohia, SE1
Crawford, CG1
van Alphen, GW1
Cook, HW1
Lands, WE1
Wilhelm, PB1
Alphen, GW1
Masumoto, S1
Masuda, C1
Chilvers, ER1
Giembycz, MA1
Challiss, RA1
Barnes, BJ1
Nahorski, SR1
McGrath, JC2
Monaghan, S1
Templeton, AG1
Wilson, VG1
MacLennan, SJ1
Whittle, MJ1
Lohuis, JA1
Van Leeuwen, W1
Verheijden, JH1
Brand, A1
Van Miert, AS1
Bowman, A1
Gillespie, JS1
Soares-da-Silva, P1
Nakazato, F1
Hirano, K1
Sato, T1
Ohashi, M1
Koike, K1
Iwasaki, S1
Nagai, H1
Kuipers, H1
Keizer, HA1
Verstappen, FT1
Costill, DL1

Trials

1 trial available for flurbiprofen and Muscle Contraction

ArticleYear
Influence of a prostaglandin-inhibiting drug on muscle soreness after eccentric work.
    International journal of sports medicine, 1985, Volume: 6, Issue:6

    Topics: Adult; Exercise Test; Flurbiprofen; Glycogen; Humans; Inflammation; Male; Muscle Contraction; Muscle

1985

Other Studies

20 other studies available for flurbiprofen and Muscle Contraction

ArticleYear
The individual and combined effects of U50,488, and flurbiprofen axetil on visceral pain in conscious rats.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:6

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Abdominal

2009
Treatment with a nitric oxide-donating NSAID alleviates functional muscle ischemia in the mouse model of Duchenne muscular dystrophy.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Disease Models, Animal; F

2012
Intrathecally applied flurbiprofen produces an endocannabinoid-dependent antinociception in the rat formalin test.
    The European journal of neuroscience, 2003, Volume: 17, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cannabinoid Receptor Modulators; Cyclo

2003
Noradrenaline-induced contraction mediated by endothelial COX-1 metabolites in the rat coronary artery.
    Journal of cardiovascular pharmacology, 2003, Volume: 42 Suppl 1

    Topics: Animals; Arachidonic Acid; Coronary Vessels; Cyclooxygenase 1; Dose-Response Relationship, Drug; Dru

2003
An in vitro study of corpus cavernosum and aorta from mice lacking the inducible nitric oxide synthase gene.
    Nitric oxide : biology and chemistry, 2003, Volume: 9, Issue:4

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Elect

2003
Lack of effect of leukotriene D4 on Ca-uptake in airway smooth muscle.
    British journal of pharmacology, 1984, Volume: 83, Issue:2

    Topics: Animals; Calcium; Flurbiprofen; Guinea Pigs; In Vitro Techniques; Lanthanum; Male; Muscle Contractio

1984
The potentiation of arterial contraction with platelet activating factor.
    Pflugers Archiv : European journal of physiology, 1984, Volume: 400, Issue:2

    Topics: Animals; Calmodulin; Carotid Arteries; Flurbiprofen; Muscle Contraction; Muscle, Smooth, Vascular; P

1984
Anti-inflammatory medication after muscle injury. A treatment resulting in short-term improvement but subsequent loss of muscle function.
    The Journal of bone and joint surgery. American volume, 1995, Volume: 77, Issue:10

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Desmin; Flurbiprofen; Isometric Contra

1995
Eicosanoid-induced Ca2+ release and sustained contraction in Ca(2+)-free media are mediated by different signal transduction pathways in rat aorta.
    British journal of pharmacology, 1993, Volume: 110, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Calciu

1993
Effect of inhibition of cyclooxygenase on pre- and postjunctional actions of peroxides in the iris-ciliary body.
    Neurochemical research, 2000, Volume: 25, Issue:4

    Topics: Animals; Benzene Derivatives; Carbachol; Cattle; Cholinergic Agonists; Ciliary Body; Cyclooxygenase

2000
The effect of precursors, products, and product analogs of prostaglandin cyclooxygenase upon iris sphincter muscle.
    Life sciences, 1978, Sep-25, Volume: 23, Issue:12

    Topics: Animals; Cats; Fatty Acids; Fatty Acids, Unsaturated; Flurbiprofen; Hydroxy Acids; In Vitro Techniqu

1978
Potentiation of PG effects on the intraocular muscles of the cat by inhibition of PG synthesis.
    Documenta ophthalmologica. Advances in ophthalmology, 1977, Feb-28, Volume: 42, Issue:2

    Topics: Animals; Cats; Ciliary Body; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Syner

1977
[Inhibitory effect of 2-(2-fluoro-4-biphenylyl)propionic acid (Flurbiprofen) on prostaglandin synthesis].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976, Volume: 72, Issue:8

    Topics: Animals; Arachidonic Acids; Carrageenan; Chromatography, Thin Layer; Drug Synergism; Edema; Flurbipr

1976
Lack of effect of zaprinast on methacholine-induced contraction and inositol 1,4,5-trisphosphate accumulation in bovine tracheal smooth muscle.
    British journal of pharmacology, 1991, Volume: 103, Issue:1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cattle; Cyclic GMP; Flurbiprofen; In Vitro Techniques;

1991
Effects of basal and acetylcholine-induced release of endothelium-derived relaxing factor on contraction to alpha-adrenoceptor agonists in a rabbit artery and corresponding veins.
    British journal of pharmacology, 1990, Volume: 99, Issue:1

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Arteries; Endothelium, Vascular; Female; Flurbipr

1990
Inhibition of the oxygen-induced contraction of the isolated human umbilical artery by indomethacin, flurbiprofen, aspirin and drugs modifying Ca2+ disposition.
    Prostaglandins, 1988, Volume: 36, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Flunixin meglumine and flurbiprofen in cows with experimental Escherichia coli mastitis.
    The Veterinary record, 1989, Mar-25, Volume: 124, Issue:12

    Topics: Animals; Body Temperature; Cattle; Clonixin; Escherichia coli Infections; Female; Flurbiprofen; Hear

1989
A comparison of the action of the endothelium-derived relaxant factor and the inhibitory factor from the bovine retractor penis on rabbit aortic smooth muscle.
    British journal of pharmacology, 1986, Volume: 87, Issue:1

    Topics: Animals; Carbachol; Catechols; Cattle; Endothelium; Flurbiprofen; Guanylate Cyclase; In Vitro Techni

1986
Epithelium selectively controls hypersensitization of the response of smooth muscle to leukotriene D4 by endogenous prostanoid(s) in guinea-pig trachea.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:3

    Topics: Animals; Dinoprost; Epithelium; Female; Flurbiprofen; Guinea Pigs; Histamine; In Vitro Techniques; M

1988
Anti-leukotriene D4 action of a new anti-asthmatic drug (KC-404) on the guinea-pig isolated trachea.
    General pharmacology, 1986, Volume: 17, Issue:3

    Topics: Animals; Calcium Chloride; Cecum; Flurbiprofen; Guinea Pigs; Histamine; In Vitro Techniques; Male; M

1986