flurbiprofen has been researched along with Miosis in 14 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
Miosis: Pupillary constriction. This may result from congenital absence of the dilatator pupillary muscle, defective sympathetic innervation, or irritation of the CONJUNCTIVA or CORNEA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy of two topical nonsteroidal anti-inflammatory drugs, diclofenac sodium and flurbiprofen, commonly used prior to cataract surgery to inhibit surgically induced miosis." | 9.08 | Comparison of diclofenac sodium and flurbiprofen for inhibition of surgically induced miosis. ( Roberts, CW, 1996) |
| "03% flurbiprofen sodium ophthalmic solution (Ocufen, Allergen Pharmaceuticals) on the inhibition of surgically induced miosis during phacoemulsification cataract surgery." | 9.08 | Topical 0.5% ketorolac vs 0.03% flurbiprofen for inhibition of miosis during cataract surgery. ( Apple, DJ; Solomon, KD; Stewart, JA; Turkalj, JW; Whiteside, SB, 1997) |
| "To investigate the mechanism by which pilocarpine causes increased aqueous humor (AH) flare, hypotony, and miosis in dogs." | 7.70 | Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs. ( Gionfriddo, J; Krohne, SG; Morrison, EA, 1998) |
| " Other factors evaluated were the effect of preoperative flurbiprofen (Ocufen) in preventing intraoperative miosis and on postoperative discomfort and the effect of incision size and intraocular carbachol (Miostat) on postoperative comfort." | 5.08 | Efficacy of diclofenac sodium solution in reducing discomfort after cataract surgery. ( Fry, LL, 1995) |
| "To compare the efficacy of two topical nonsteroidal anti-inflammatory drugs, diclofenac sodium and flurbiprofen, commonly used prior to cataract surgery to inhibit surgically induced miosis." | 5.08 | Comparison of diclofenac sodium and flurbiprofen for inhibition of surgically induced miosis. ( Roberts, CW, 1996) |
| "03% flurbiprofen sodium ophthalmic solution (Ocufen, Allergen Pharmaceuticals) on the inhibition of surgically induced miosis during phacoemulsification cataract surgery." | 5.08 | Topical 0.5% ketorolac vs 0.03% flurbiprofen for inhibition of miosis during cataract surgery. ( Apple, DJ; Solomon, KD; Stewart, JA; Turkalj, JW; Whiteside, SB, 1997) |
| "03% flurbiprofen in preventing intraoperative miosis was evaluated by a prospective randomized, double-masked controlled trial of 60 patients." | 5.07 | Effect of flurbiprofen sodium on pupillary dilatation during scleral buckling surgery. ( Mitra, S; Murugesan, R; Ravishankar, KV; Roysarkar, TK; Shanmugam, MP, 1994) |
| "To investigate the mechanism by which pilocarpine causes increased aqueous humor (AH) flare, hypotony, and miosis in dogs." | 3.70 | Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs. ( Gionfriddo, J; Krohne, SG; Morrison, EA, 1998) |
| "To compare the bioavailability and pupillary effect of flurbiprofen and indomethacin during phacoemulsification and intraocular lens implantation." | 2.68 | Intraocular availability and pupillary effect of flurbiprofen and indomethacin during cataract surgery. ( Cheetham, JK; DeGryse, R; Garcia, CG; Gimbel, H; Van Westenbrugge, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (85.71) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fry, LL | 1 |
| Roysarkar, TK | 1 |
| Mitra, S | 1 |
| Shanmugam, MP | 1 |
| Ravishankar, KV | 1 |
| Murugesan, R | 1 |
| Allaire, C | 1 |
| Lablache Combier, M | 1 |
| Trinquand, C | 1 |
| Bazin, R | 1 |
| Gimbel, H | 1 |
| Van Westenbrugge, J | 1 |
| Cheetham, JK | 1 |
| DeGryse, R | 1 |
| Garcia, CG | 1 |
| Roberts, CW | 1 |
| Solomon, KD | 1 |
| Turkalj, JW | 1 |
| Whiteside, SB | 1 |
| Stewart, JA | 1 |
| Apple, DJ | 1 |
| Krohne, SG | 1 |
| Gionfriddo, J | 1 |
| Morrison, EA | 1 |
| Gaynes, BI | 1 |
| Deutsch, TA | 1 |
| Snyder, RW | 1 |
| Siekert, RW | 1 |
| Schwiegerling, J | 1 |
| Donnenfeld, E | 1 |
| Thompson, P | 1 |
| Pignatello, R | 1 |
| Bucolo, C | 1 |
| Spedalieri, G | 1 |
| Maltese, A | 1 |
| Puglisi, G | 1 |
| Psilas, K | 1 |
| Kalogeropoulos, C | 1 |
| Loucatzicos, E | 1 |
| Asproudis, I | 1 |
| Petroutsos, G | 1 |
| Holmes, JM | 1 |
| Jay, WM | 1 |
| Bito, LZ | 1 |
| Smiddy, WE | 1 |
| Glaser, BM | 1 |
| Michels, RG | 1 |
| Vitale, S | 1 |
10 trials available for flurbiprofen and Miosis
| Article | Year |
|---|---|
Efficacy of diclofenac sodium solution in reducing discomfort after cataract surgery.
Topics: Administration, Topical; Carbachol; Cataract Extraction; Diclofenac; Flurbiprofen; Humans; Lenses, I | 1995 |
Effect of flurbiprofen sodium on pupillary dilatation during scleral buckling surgery.
Topics: Adult; Double-Blind Method; Female; Flurbiprofen; Humans; Male; Middle Aged; Miosis; Prospective Stu | 1994 |
[Comparative efficacy of 0.1% indomethacin eyedrops, 0.03% flurbiprofen eyedrops and placebo for maintaining peroperative mydriasis].
Topics: Adult; Aged; Cataract Extraction; Double-Blind Method; Female; Flurbiprofen; Humans; Indomethacin; I | 1994 |
Intraocular availability and pupillary effect of flurbiprofen and indomethacin during cataract surgery.
Topics: Absorption; Adult; Aged; Aged, 80 and over; Aqueous Humor; Biological Availability; Cyclooxygenase I | 1996 |
Comparison of diclofenac sodium and flurbiprofen for inhibition of surgically induced miosis.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Flurbiprofen; | 1996 |
Topical 0.5% ketorolac vs 0.03% flurbiprofen for inhibition of miosis during cataract surgery.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cy | 1997 |
Acular as a single agent for use as an antimiotic and anti-inflammatory in cataract surgery.
Topics: Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Cell Count; Drug Adm | 2000 |
The effect of indomethacin, diclofenac and flurbiprofen on the maintenance of mydriasis during extracapsular cataract extraction.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Diclofenac; Flurbiprofen; Humans; Indomethacin; Intrao | 1992 |
The effect of preoperative flurbiprofen on miosis produced by acetylcholine during cataract surgery.
Topics: Acetylcholine; Administration, Topical; Aged; Cataract Extraction; Double-Blind Method; Flurbiprofen | 1991 |
Miosis during vitreoretinal surgery.
Topics: Chi-Square Distribution; Flurbiprofen; Humans; Intraoperative Complications; Miosis; Preoperative Ca | 1990 |
4 other studies available for flurbiprofen and Miosis
| Article | Year |
|---|---|
Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs.
Topics: Administration, Topical; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Aqueous Humor; Diclo | 1998 |
Cost-effectiveness of topical 0.03% flurbiprofen in outpatient cataract surgery as measured by surgical time and vitreous loss.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-S | 1998 |
Flurbiprofen-loaded acrylate polymer nanosuspensions for ophthalmic application.
Topics: Acrylic Resins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biocompatible Materials; Biologica | 2002 |
Surgical miosis: have we been misled by a bunch of rabbits?
Topics: Animals; Cyclooxygenase Inhibitors; Eicosanoic Acids; Flurbiprofen; Humans; Miosis; Ophthalmologic S | 1990 |