flurbiprofen has been researched along with Macular Edema in 8 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
Macular Edema: Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)
| Excerpt | Relevance | Reference |
|---|---|---|
| "03% flurbiprofen and 1% indomethacin, for their ability to prevent pseudophakic cystoid macular edema (CME)." | 9.08 | Efficacy of topical flurbiprofen and indomethacin in preventing pseudophakic cystoid macular edema. Flurbiprofen-CME Study Group I. ( Solomon, LD, 1995) |
| "Flurbiprofen treatment improved contrast sensitivity in patients with and without CME significantly at 12 cycles per degree." | 6.68 | Effects of flurbiprofen and indomethacin on acute cystoid macular edema after cataract surgery: functional vision and contrast sensitivity. ( Abelson, M; Cheetham, JK; DeGryse, RE; Ginsburg, AP, 1995) |
| "03% flurbiprofen and 1% indomethacin, for their ability to prevent pseudophakic cystoid macular edema (CME)." | 5.08 | Efficacy of topical flurbiprofen and indomethacin in preventing pseudophakic cystoid macular edema. Flurbiprofen-CME Study Group I. ( Solomon, LD, 1995) |
| "Flurbiprofen treatment improved contrast sensitivity in patients with and without CME significantly at 12 cycles per degree." | 2.68 | Effects of flurbiprofen and indomethacin on acute cystoid macular edema after cataract surgery: functional vision and contrast sensitivity. ( Abelson, M; Cheetham, JK; DeGryse, RE; Ginsburg, AP, 1995) |
| "No adverse events were observed during pharmacokinetic assessment." | 1.46 | Pharmacokinetics and efficacy of intraocular flurbiprofen. ( Blazaki, S; Naoumidi, E; Tsatsakis, A; Tsatsanis, C; Tsika, C; Tsilimbaris, MK; Tzatzarakis, M, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blazaki, S | 1 |
| Tsika, C | 1 |
| Tzatzarakis, M | 1 |
| Naoumidi, E | 1 |
| Tsatsakis, A | 1 |
| Tsatsanis, C | 1 |
| Tsilimbaris, MK | 1 |
| Shorstein, NH | 1 |
| Liu, L | 1 |
| Waxman, MD | 1 |
| Herrinton, LJ | 1 |
| Curković, T | 1 |
| Vukojević, N | 1 |
| Bućan, K | 1 |
| Solomon, LD | 1 |
| Ginsburg, AP | 1 |
| Cheetham, JK | 1 |
| DeGryse, RE | 1 |
| Abelson, M | 1 |
| Gomolin, JE | 1 |
| Koenekoop, RK | 1 |
| Mishima, H | 1 |
| Masuda, K | 1 |
| Miyake, K | 1 |
| Shimada, H | 1 |
| Kawamura, A | 1 |
| Koga, S | 1 |
| Shingyouchi, F | 1 |
| Matsui, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluating the Efficacy, Compliance, and Patient Satisfaction of a New Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population[NCT05157113] | Phase 4 | 70 participants (Anticipated) | Interventional | 2022-05-31 | Recruiting | ||
| Evaluation of Macular Thickness in Patients With Glaucoma in Use of Topical Prostaglandin Analogue Undergoing Trabeculectomy With Mitomycin C[NCT06000280] | 37 participants (Actual) | Interventional | 2021-01-04 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for flurbiprofen and Macular Edema
| Article | Year |
|---|---|
The putative role of prostaglandins in cystoid macular edema.
Topics: Aqueous Humor; Cataract Extraction; Diclofenac; Fluorescein Angiography; Flurbiprofen; Humans; Indom | 1989 |
4 trials available for flurbiprofen and Macular Edema
| Article | Year |
|---|---|
Treatment of pseudophakic cystoid macular oedema.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Anti-Inflammatory Agents; Anti-Inflamm | 2005 |
Efficacy of topical flurbiprofen and indomethacin in preventing pseudophakic cystoid macular edema. Flurbiprofen-CME Study Group I.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cataract Extraction; Contrast Sensitivity; | 1995 |
Effects of flurbiprofen and indomethacin on acute cystoid macular edema after cataract surgery: functional vision and contrast sensitivity.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Cataract Extraction; Contrast Sensitivity; Double-Bli | 1995 |
Presumed photic retinopathy after cataract surgery: an angiographic study.
Topics: Cataract Extraction; Fluorescein Angiography; Flurbiprofen; Follow-Up Studies; Fundus Oculi; Humans; | 1993 |
3 other studies available for flurbiprofen and Macular Edema
| Article | Year |
|---|---|
Pharmacokinetics and efficacy of intraocular flurbiprofen.
Topics: Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Endoph | 2017 |
Comparative Effectiveness of Three Prophylactic Strategies to Prevent Clinical Macular Edema after Phacoemulsification Surgery.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofena | 2015 |
[Effects of an anti-prostaglandin agent added to the irrigation solution on macular edema in monkey eyes induced by pars plana vitrectomy].
Topics: Animals; Flurbiprofen; Macaca; Macular Edema; Postoperative Complications; Propionates; Prostaglandi | 1987 |