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flurbiprofen and Kidney Failure, Chronic

flurbiprofen has been researched along with Kidney Failure, Chronic in 3 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
" Flurbiprofen half-life and Tmax were not different."2.67Pharmacokinetic comparison of flurbiprofen in end-stage renal disease subjects and subjects with normal renal function. ( Cefali, EA; Cox, S; Poynor, WJ; Sica, D, 1991)
"Flurbiprofen is a chiral nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid class."2.39Clinical pharmacokinetics of flurbiprofen and its enantiomers. ( Davies, NM, 1995)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smith, MD1
Hardy, G1
Williams, JD1
Coles, GA1
Davies, NM1
Cefali, EA1
Poynor, WJ1
Sica, D1
Cox, S1

Reviews

1 review available for flurbiprofen and Kidney Failure, Chronic

ArticleYear
Clinical pharmacokinetics of flurbiprofen and its enantiomers.
    Clinical pharmacokinetics, 1995, Volume: 28, Issue:2

    Topics: Absorption; Administration, Oral; Aging; Blood Proteins; Delayed-Action Preparations; Dose-Response

1995

Trials

1 trial available for flurbiprofen and Kidney Failure, Chronic

ArticleYear
Pharmacokinetic comparison of flurbiprofen in end-stage renal disease subjects and subjects with normal renal function.
    Journal of clinical pharmacology, 1991, Volume: 31, Issue:9

    Topics: Adult; Female; Flurbiprofen; Hemodialysis Solutions; Humans; Isomerism; Kidney Failure, Chronic; Mal

1991

Other Studies

1 other study available for flurbiprofen and Kidney Failure, Chronic

ArticleYear
Suppressor cell numbers and activity in non-transfused renal dialysis patients.
    Clinical nephrology, 1983, Volume: 20, Issue:3

    Topics: Adult; Concanavalin A; Female; Flurbiprofen; Humans; Immunity, Cellular; Kidney Failure, Chronic; Le

1983