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flurbiprofen and Kidney Diseases

flurbiprofen has been researched along with Kidney Diseases in 7 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Flurbiprofen, however, was faster-acting and superior to dipirone + hyoscine in the overall evaluation of good and excellent therapeutic response rates."2.68[Flubiprofen vs dipyrone combined with hyoscine: the analgesic efficacy in renal colic]. ( Arrizabalaga Moreno, M; Camp Herrero, J; del Nogal Saez, F; Domínguez Granados, R; Extramiana Cameno, J; Gimeno Albo, F; Milla Santos, J; Mora Durban, MJ; Moreno Carretero, E; Paniagua Andrés, P, 1995)
" Renal function was assessed in eight patients with chronic renal insufficiency following the administration of flurbiprofen 50 mg as a single dose and after chronic administration of 50 mg four times daily for 8 and 27 days."2.67Effects of flurbiprofen on renal function in patients with moderate renal insufficiency. ( Brater, DC; Greene, PK; Hall, SD; Manatunga, AK; Murray, MD, 1992)
" CDDP-induced nephrotoxicity (CIN) is one of the most severe adverse events associated with the use of CDDP."1.56Comparison of the nephroprotective effects of non-steroidal anti-inflammatory drugs on cisplatin-induced nephrotoxicity in vitro and in vivo. ( Furugen, A; Iseki, K; Kobayashi, M; Narumi, K; Okamoto, K; Saito, Y, 2020)
"Flurbiprofen-treated rats showed severe gastrointestinal ulcerations (bleeding in 3/8 rats) and nefrotoxicity, which was not observed in nitroflurbiprofen-treated cirrhotic rats."1.34Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portal hypertension in rats. ( Fevery, J; Laleman, W; Nevens, F; Van der Elst, I; Van Landeghem, L; Zeegers, M, 2007)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (57.14)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Okamoto, K1
Saito, Y1
Narumi, K1
Furugen, A1
Iseki, K1
Kobayashi, M1
Gonçalves, AR1
Fujihara, CK1
Mattar, AL1
Malheiros, DM1
Noronha, Ide L1
de Nucci, G1
Zatz, R1
Laleman, W1
Van Landeghem, L1
Van der Elst, I1
Zeegers, M1
Fevery, J1
Nevens, F1
Blouin, R1
Chaudhary, I1
Nishihara, K1
Cox, S1
Mora Durban, MJ1
Extramiana Cameno, J1
Arrizabalaga Moreno, M1
Paniagua Andrés, P1
Camp Herrero, J1
Milla Santos, J1
del Nogal Saez, F1
Gimeno Albo, F1
Moreno Carretero, E1
Domínguez Granados, R1
Julián Mora, M1
Extramiana, J1
Navarro, FJ1
Arrizabalaga, M1
Mañas, A1
González, P1
Pérez, MJ1
Paniagua, P1
Murray, MD1
Greene, PK1
Brater, DC1
Manatunga, AK1
Hall, SD1

Trials

3 trials available for flurbiprofen and Kidney Diseases

ArticleYear
[Flubiprofen vs dipyrone combined with hyoscine: the analgesic efficacy in renal colic].
    Archivos espanoles de urologia, 1995, Volume: 48, Issue:9

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Butylscopola

1995
[Flurbiprofen: therapeutic alternative in nephritic colic].
    Archivos espanoles de urologia, 1992, Volume: 45, Issue:8

    Topics: Adult; Aged; Colic; Dipyrone; Double-Blind Method; Drug Therapy, Combination; Female; Flurbiprofen;

1992
Effects of flurbiprofen on renal function in patients with moderate renal insufficiency.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:4

    Topics: Aged; Blood Pressure; Body Weight; Female; Flurbiprofen; Hemodynamics; Humans; Indomethacin; Kidney;

1992

Other Studies

4 other studies available for flurbiprofen and Kidney Diseases

ArticleYear
Comparison of the nephroprotective effects of non-steroidal anti-inflammatory drugs on cisplatin-induced nephrotoxicity in vitro and in vivo.
    European journal of pharmacology, 2020, Oct-05, Volume: 884

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Celecoxib; Cell Line; Cisplatin; Cytopr

2020
Renal expression of COX-2, ANG II, and AT1 receptor in remnant kidney: strong renoprotection by therapy with losartan and a nonsteroidal anti-inflammatory.
    American journal of physiology. Renal physiology, 2004, Volume: 286, Issue:5

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cyclooxyg

2004
Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portal hypertension in rats.
    Gastroenterology, 2007, Volume: 132, Issue:2

    Topics: Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Endoth

2007
The effects of liver and renal disease on stereoselective serum binding of flurbiprofen.
    British journal of clinical pharmacology, 1993, Volume: 35, Issue:1

    Topics: Adult; Aged; Blood Proteins; Flurbiprofen; Humans; Kidney Diseases; Liver Diseases; Male; Middle Age

1993