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flurbiprofen and Intraocular Pressure

flurbiprofen has been researched along with Intraocular Pressure in 25 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"We performed a prospective study that evaluated whether pretreatment with topical flurbiprofen alters the intraocular pressure (IOP) lowering effects of either topical 1% apraclonidine hydrochloride or 0."9.07Effects of topical flurbiprofen on the intraocular pressure lowering effects of apraclonidine and timolol. ( Arkin, LM; Cummings, HL; Robin, AL; Sulewski, ME, 1991)
"To investigate the mechanism by which pilocarpine causes increased aqueous humor (AH) flare, hypotony, and miosis in dogs."7.70Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs. ( Gionfriddo, J; Krohne, SG; Morrison, EA, 1998)
"The onset of ocular hypertension occurred within 15 min."5.28Argon laser-induced ocular hypertension: animal model of ocular inflammation. ( Gherezghiher, T; Koss, MC, 1989)
"In eyes with low to moderate myopia, the steroid and diclofenac subgroups had significantly different refractions 2 and 4 months postoperatively but no difference at 6 months; subjective haze grading was consistently lower in the steroid subgroup than in the NSAID subgroups (flurbiprofen, diclofenac) after 2 months."5.08Short-term effects of flurbiprofen and diclofenac on refractive outcome and corneal haze after photorefractive keratectomy. ( Baek, SH; Chang, JH; Choi, SY; Lee, JH; Wee, WR, 1997)
"Seventy glaucomatous eyes received argon laser trabeculoplasty (ALT) to 180 degrees of the trabecular meshwork."5.05Nonsteroidal anti-inflammatory agents after argon laser trabeculoplasty. A trial with flurbiprofen and indomethacin. ( Hotchkiss, ML; Pollack, IP; Quigley, HA; Robin, AL, 1984)
" Topical administration of diclofenac and flurbiprofen should be used with caution in cats with a history of ocular hypertension."3.77Evaluation of four drugs for inhibition of paracentesis-induced blood-aqueous humor barrier breakdown in cats. ( Khrone, SG; Rankin, AJ; Stiles, J, 2011)
"To investigate the mechanism by which pilocarpine causes increased aqueous humor (AH) flare, hypotony, and miosis in dogs."3.70Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs. ( Gionfriddo, J; Krohne, SG; Morrison, EA, 1998)
"Effects of topical flurbiprofen, a highly potent prostaglandin synthetase inhibitor, were evaluated during planned extracapsular cataract extraction in diabetic and nondiabetic patients."3.68Topical flurbiprofen in intraocular surgery on diabetic and nondiabetic patients. ( Takase, M; Tsuchisaka, H, 1990)
" The X-ray-induced ocular inflammation, particularly the rise in intraocular pressure, was found to be inhibited by intravenous pretreatment of rabbits with flurbiprofen, indomethacin, or imidazole (1, 10, and 100 mg/kg i."3.66The role of the arachidonic acid cascade in the species-specific X-ray-induced inflammation of the rabbit eye. ( Bito, LZ; Klein, EM, 1982)
"The onset of ocular hypertension occurred within 15 min."1.28Argon laser-induced ocular hypertension: animal model of ocular inflammation. ( Gherezghiher, T; Koss, MC, 1989)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19908 (32.00)18.7374
1990's13 (52.00)18.2507
2000's2 (8.00)29.6817
2010's2 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pirie, CG1
Maranda, LS1
Pizzirani, S1
Rankin, AJ1
Khrone, SG1
Stiles, J1
Ohia, SE2
Zhan, GL3
Leday, AM1
Opere, CA1
Kulkarni, KH1
Harris, LC1
Roche, VF1
Nessim, M1
Kyprianou, I1
Kumar, V1
Murray, PI1
Hotchkiss, ML1
Robin, AL3
Pollack, IP1
Quigley, HA1
Weinreb, RN1
Baerveldt, G1
Drake, MV1
Blumenthal, M1
Wilensky, J1
Bito, LZ1
Klein, EM1
Gieser, DK1
Hodapp, E1
Goldberg, I1
Kass, MA1
Becker, B1
Duffin, RM1
Christensen, RE1
Bergamini, MV1
Goethals, M1
Missotten, L1
Mengi, SA1
Deshpande, SG1
Baek, SH1
Choi, SY1
Chang, JH1
Wee, WR1
Lee, JH1
Krohne, SG1
Gionfriddo, J1
Morrison, EA1
Toris, CB1
Camras, CB5
Wang, YL2
Yablonski, ME1
Koçak, I1
Yalvaç, IS1
Koçak, A1
Nurözler, A1
Unlü, N1
Kasim, R1
Duman, S1
Black, EH1
Cohen, KL1
Tripoli, NK1
Winslow, PA1
Ohia, EO1
Siegel, MJ1
Lustgarten, JS1
Podos, SM3
Mancino, M1
Ohia, E1
Kulkarni, P1
Sulewski, ME1
Cummings, HL1
Arkin, LM1
Millichamp, NJ1
Dziezyc, J1
Tsuchisaka, H1
Takase, M1
Wang, RF1
Lee, KW1
Bhuyan, KC1
Bhuyan, DK1
Gherezghiher, T1
Koss, MC1

Reviews

1 review available for flurbiprofen and Intraocular Pressure

ArticleYear
The role of endogenous prostaglandins in clinically-used and investigational glaucoma therapy.
    Progress in clinical and biological research, 1989, Volume: 312

    Topics: Animals; Cyclooxygenase Inhibitors; Flurbiprofen; Glaucoma; Humans; Indomethacin; Intraocular Pressu

1989

Trials

10 trials available for flurbiprofen and Intraocular Pressure

ArticleYear
Effect of topical 0.03% flurbiprofen and 0.005% latanoprost, alone and in combination, on normal canine eyes.
    Veterinary ophthalmology, 2011, Volume: 14, Issue:2

    Topics: Acclimatization; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Dogs; Eye; Fl

2011
Nonsteroidal anti-inflammatory agents after argon laser trabeculoplasty. A trial with flurbiprofen and indomethacin.
    Ophthalmology, 1984, Volume: 91, Issue:8

    Topics: Adult; Aged; Argon; Clinical Trials as Topic; Double-Blind Method; Eye Diseases; Female; Flurbiprofe

1984
Flurbiprofen pretreatment in argon laser trabeculoplasty for primary open-angle glaucoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:11

    Topics: Aged; Double-Blind Method; Female; Flurbiprofen; Glaucoma, Open-Angle; Humans; Inflammation; Intraoc

1984
Flurbiprofen and intraocular pressure.
    Annals of ophthalmology, 1981, Volume: 13, Issue:7

    Topics: Adult; Aged; Clinical Trials as Topic; Dexamethasone; Double-Blind Method; Female; Flurbiprofen; Hum

1981
Efficacy and safety of indomethacin 0.1% versus flurbiprofen 0.03% eyedrops in inflammation after argon laser trabeculoplasty. The Belgian Study Group on Glaucoma.
    Documenta ophthalmologica. Advances in ophthalmology, 1994, Volume: 85, Issue:3

    Topics: Double-Blind Method; Drug Tolerance; Endophthalmitis; Female; Flurbiprofen; Glaucoma, Open-Angle; Hu

1994
Short-term effects of flurbiprofen and diclofenac on refractive outcome and corneal haze after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 1997, Volume: 23, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Opacity; D

1997
Comparison of the anti-inflammatory effects of diclofenac and flurbiprofen eye drops after cataract extraction.
    Acta ophthalmologica Scandinavica, 1998, Volume: 76, Issue:3

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Cornea; Diclofenac; Double-Blind

1998
Necessity of the Honan intraocular pressure reducer in cataract surgery using topical anesthesia.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:2

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cataract Extraction; Cornea; Female; Flurb

1999
Effect of flurbiprofen on the reduction of intraocular pressure after administration of 1% apraclonidine in patients with glaucoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1992, Volume: 110, Issue:5

    Topics: Clonidine; Flurbiprofen; Glaucoma; Humans; Intraocular Pressure; Osmolar Concentration

1992
Effects of topical flurbiprofen on the intraocular pressure lowering effects of apraclonidine and timolol.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:6

    Topics: Administration, Topical; Adrenergic alpha-Agonists; Adult; Clonidine; Double-Blind Method; Evaluatio

1991

Other Studies

14 other studies available for flurbiprofen and Intraocular Pressure

ArticleYear
Evaluation of four drugs for inhibition of paracentesis-induced blood-aqueous humor barrier breakdown in cats.
    American journal of veterinary research, 2011, Volume: 72, Issue:6

    Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents; Aqueous Humor; Blood-Aqueous Barrier; Cat Disea

2011
Ocular pharmacology of bicyclic hexahydroaporphines.
    Methods and findings in experimental and clinical pharmacology, 2005, Volume: 27, Issue:2

    Topics: Animals; Aporphines; Bridged Bicyclo Compounds; Cattle; Cyclooxygenase Inhibitors; Eye; Flurbiprofen

2005
Anterior scleritis, scleral thinning, and intraocular pressure measurement.
    Ocular immunology and inflammation, 2005, Volume: 13, Issue:6

    Topics: Anti-Inflammatory Agents; Disease Progression; Drug Therapy, Combination; Female; Flurbiprofen; Huma

2005
The role of the arachidonic acid cascade in the species-specific X-ray-induced inflammation of the rabbit eye.
    Investigative ophthalmology & visual science, 1982, Volume: 22, Issue:5

    Topics: Animals; Arachidonic Acids; Cromolyn Sodium; Endophthalmitis; Eye; Female; Flurbiprofen; Imidazoles;

1982
Suppression of adrenergic adaptation in the eye with a prostaglandin synthesis inhibitor.
    Investigative ophthalmology & visual science, 1981, Volume: 21, Issue:5

    Topics: Adaptation, Ocular; Animals; Female; Flurbiprofen; Intraocular Pressure; Male; Norepinephrine; Propi

1981
Comparative evaluation of Butea frondosa and flurbiprofen for ocular anti-inflammatory activity in rabbits.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:12A

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Drug Evaluation, Preclinical; Endop

1995
Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs.
    American journal of veterinary research, 1998, Volume: 59, Issue:4

    Topics: Administration, Topical; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Aqueous Humor; Diclo

1998
Bunazosin reduces intraocular pressure in rabbits by increasing uveoscleral outflow.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1998, Volume: 14, Issue:3

    Topics: Administration, Topical; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aqueous Humor;

1998
Superior cervical ganglionectomy-induced lowering of intraocular pressure in rabbits: role of prostaglandins and neuropeptide Y.
    General pharmacology, 1999, Volume: 32, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Flurbiprofen; Ganglionectomy; Intraocular

1999
A comparative study between cod liver oil and liquid lard intake on intraocular pressure on rabbits.
    Prostaglandins, leukotrienes, and essential fatty acids, 1992, Volume: 45, Issue:3

    Topics: Administration, Topical; Animals; Aqueous Humor; Aspirin; Cod Liver Oil; Dietary Fats; Flurbiprofen;

1992
Comparison of flunixin meglumine and flurbiprofen for control of ocular irritative response in dogs.
    American journal of veterinary research, 1991, Volume: 52, Issue:9

    Topics: Animals; Clonixin; Dog Diseases; Dogs; Endophthalmitis; Flurbiprofen; Intraocular Pressure; Lasers;

1991
Topical flurbiprofen in intraocular surgery on diabetic and nondiabetic patients.
    Annals of ophthalmology, 1990, Volume: 22, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cataract; Cataract Extraction; Cyclooxygena

1990
The role of prostaglandins in the para-aminoclonidine-induced reduction of intraocular pressure.
    Transactions of the American Ophthalmological Society, 1989, Volume: 87

    Topics: Administration, Topical; Animals; Aqueous Humor; Clonidine; Dinoprost; Dinoprostone; Disease Models,

1989
Argon laser-induced ocular hypertension: animal model of ocular inflammation.
    Journal of ocular pharmacology, 1989,Spring, Volume: 5, Issue:1

    Topics: Animals; Aqueous Humor; Argon; Disease Models, Animal; Endophthalmitis; Female; Flurbiprofen; Gangli

1989