flurbiprofen has been researched along with Intestinal Diseases in 4 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response for intestinal ulcer production was observed for rac- and (S)-flurbiprofen; animals given (R)-flurbiprofen exhibited no ulcers." | 1.30 | Mechanism of enhancement of intestinal ulcerogenicity of S-aryl propionic acids by their R-enantiomers in the rat. ( Gibson, K; Kantoci, D; Leipold, D; Liu, Y; McCracken, JD; Mineyama, Y; Murray, ED; Quiggle, D; Wechter, WJ, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takeuchi, K | 1 |
| Yokota, A | 1 |
| Tanaka, A | 1 |
| Takahira, Y | 1 |
| Wechter, WJ | 2 |
| Kantoci, D | 2 |
| Murray, ED | 2 |
| Quiggle, DD | 1 |
| Leipold, DD | 1 |
| Gibson, KM | 1 |
| McCracken, JD | 2 |
| Quiggle, D | 1 |
| Leipold, D | 1 |
| Gibson, K | 1 |
| Mineyama, Y | 1 |
| Liu, Y | 1 |
| Mahmud, T | 1 |
| Somasundaram, S | 1 |
| Sigthorsson, G | 1 |
| Simpson, RJ | 1 |
| Rafi, S | 1 |
| Foster, R | 1 |
| Tavares, IA | 1 |
| Roseth, A | 1 |
| Hutt, AJ | 1 |
| Jacob, M | 1 |
| Pacy, J | 1 |
| Scott, DL | 1 |
| Wrigglesworth, JM | 1 |
| Bjarnason, I | 1 |
4 other studies available for flurbiprofen and Intestinal Diseases
| Article | Year |
|---|---|
Factors involved in upregulation of inducible nitric oxide synthase in rat small intestine following administration of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Dinoproston | 2006 |
R-flurbiprofen chemoprevention and treatment of intestinal adenomas in the APC(Min)/+ mouse model: implications for prophylaxis and treatment of colon cancer.
Topics: Adenoma; Adenomatous Polyposis Coli; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-St | 1997 |
Mechanism of enhancement of intestinal ulcerogenicity of S-aryl propionic acids by their R-enantiomers in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship | 1998 |
Enantiomers of flurbiprofen can distinguish key pathophysiological steps of NSAID enteropathy in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Blood Proteins; Cyclooxygenase Inhibit | 1998 |