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flurbiprofen and Gingivitis

flurbiprofen has been researched along with Gingivitis in 7 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Gingivitis: Inflammation of gum tissue (GINGIVA) without loss of connective tissue.

Research Excerpts

ExcerptRelevanceReference
" This double-blind parallel group study investigated the effect of a systemic flurbiprofen preparation (100 mg daily), when combined with toothbrushing on the resolution of experimental gingivitis in human volunteers."9.07The effect of systemically-administered flurbiprofen as an adjunct to toothbrushing on the resolution of experimental gingivitis. ( Heasman, PA; Kelly, PJ; Seymour, RA, 1994)
"A clinical trial was undertaken to examine the effects of a potent cyclooxygenase inhibitor, flurbiprofen, on both developing and established gingivitis in humans."9.07Flurbiprofen in the prevention and treatment of experimental gingivitis. ( Collins, JG; Edwards, G; Heasman, PA; Offenbacher, S; Seymour, RA, 1993)
"A clinical trial was undertaken to examine the effects of a potent cyclooxygenase inhibitor, flurbiprofen, on both developing and established gingivitis in humans."5.07Flurbiprofen in the prevention and treatment of experimental gingivitis. ( Collins, JG; Edwards, G; Heasman, PA; Offenbacher, S; Seymour, RA, 1993)
" On d 21 and 28, serum and CF samples were taken prior to dosing and afterwards at 1, 2, 4 and 6 hours."1.28Flurbiprofen in human crevicular fluid analyzed by high-performance liquid chromatography. ( Barrett, AW; Edwards, G; Heasman, PA; Seymour, RA; Ward, A, 1990)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's4 (57.14)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ElAttar, TM1
Lin, HS1
Tira, DE1
Heasman, PA5
Seymour, RA5
Kelly, PJ1
Offenbacher, S1
Collins, JG1
Edwards, G2
Jones, DS1
Irwin, CR1
Woolfson, AD1
Djokic, J1
Adams, V1
Ward, A1
Barrett, AW1
Boston, PF1

Trials

5 trials available for flurbiprofen and Gingivitis

ArticleYear
The effect of systemically-administered flurbiprofen as an adjunct to toothbrushing on the resolution of experimental gingivitis.
    Journal of clinical periodontology, 1994, Volume: 21, Issue:3

    Topics: Administration, Oral; Adult; Dental Plaque Index; Double-Blind Method; Female; Flurbiprofen; Gingivi

1994
Flurbiprofen in the prevention and treatment of experimental gingivitis.
    Journal of clinical periodontology, 1993, Volume: 20, Issue:10

    Topics: Adult; Dinoprostone; Female; Flurbiprofen; Gingival Crevicular Fluid; Gingivitis; Humans; Leukotrien

1993
Physicochemical characterization and preliminary in vivo efficacy of bioadhesive, semisolid formulations containing flurbiprofen for the treatment of gingivitis.
    Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:6

    Topics: Acrylic Resins; Adhesiveness; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Compressive Streng

1999
The effect of a systemically-administered non-steroidal anti-inflammatory drug (flurbiprofen) on experimental gingivitis in humans.
    Journal of clinical periodontology, 1989, Volume: 16, Issue:9

    Topics: Administration, Oral; Adult; Dental Plaque Index; Female; Flurbiprofen; Gingival Crevicular Fluid; G

1989
The effect of a topical non-steroidal anti-inflammatory drug on the development of experimental gingivitis in man.
    Journal of clinical periodontology, 1989, Volume: 16, Issue:6

    Topics: Administration, Topical; Adult; Dental Plaque; Double-Blind Method; Female; Flurbiprofen; Gingivitis

1989

Other Studies

2 other studies available for flurbiprofen and Gingivitis

ArticleYear
Arachidonic acid metabolism in inflamed gingiva and its inhibition by anti-inflammatory drugs.
    Journal of periodontology, 1984, Volume: 55, Issue:9

    Topics: Anti-Inflammatory Agents; Arachidonic Acids; Flurbiprofen; Gingivitis; Humans; Periodontal Diseases;

1984
Flurbiprofen in human crevicular fluid analyzed by high-performance liquid chromatography.
    Journal of periodontal research, 1990, Volume: 25, Issue:2

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Female; Flurbiprofen; Gingival Cr

1990