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flurbiprofen and Gastrointestinal Hemorrhage

flurbiprofen has been researched along with Gastrointestinal Hemorrhage in 8 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.

Research Excerpts

ExcerptRelevanceReference
"(R)- flurbiprofen was not statistically significant."2.69Clinical endoscopic evaluation of the gastroduodenal tolerance to (R)- ketoprofen, (R)- flurbiprofen, racemic ketoprofen, and paracetamol: a randomized, single-blind, placebo-controlled trial. ( Caubet, JF; Handley, DA; Jerussi, TP; McCray, JE, 1998)
" Flurbiprofen showed a linear dose-response relationship with respect to gastric injury and serum drug levels."2.66The effects of flurbiprofen, aspirin, cimetidine, and antacids on the gastric and duodenal mucosa of normal volunteers. An endoscopic and photographic study. ( Friedman, H; Lanza, FL; Royer, GL; Schwartz, JH; Seckman, CE; Stubbs, CM, 1989)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Van Vertloo, LR1
Terhaar, HM1
Viall, AK1
Allbaugh, RA1
Yeung Laiwah, AC1
Hilditch, TE1
Horton, PW1
Hunter, JA1
Mitchell, H1
Barraclough, D1
Muirden, KD1
Wallace, JL1
Cirino, G1
McKnight, GW1
Elliott, SN1
Pierrugues, R1
Fontes, J1
Jerussi, TP1
Caubet, JF1
McCray, JE1
Handley, DA1
Vakil, BJ1
Kulkarni, RD1
Kulkarni, VN1
Mehta, DJ1
Gharpure, MB1
Pispati, PK1
Friedman, H1
Seckman, CE1
Schwartz, JH1
Lanza, FL1
Royer, GL1
Stubbs, CM1

Trials

3 trials available for flurbiprofen and Gastrointestinal Hemorrhage

ArticleYear
Clinical endoscopic evaluation of the gastroduodenal tolerance to (R)- ketoprofen, (R)- flurbiprofen, racemic ketoprofen, and paracetamol: a randomized, single-blind, placebo-controlled trial.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:2S

    Topics: Acetaminophen; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Duodenal Dise

1998
Estimation of gastro-intestinal blood loss in volunteers treated with non-steroidal anti-inflammatory agents.
    Current medical research and opinion, 1977, Volume: 5, Issue:1

    Topics: Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Feces; Flurbiprofen; Gastrointestinal

1977
The effects of flurbiprofen, aspirin, cimetidine, and antacids on the gastric and duodenal mucosa of normal volunteers. An endoscopic and photographic study.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:6

    Topics: Adult; Antacids; Aspirin; Cimetidine; Duodenum; Endoscopy; Female; Flurbiprofen; Gastric Mucosa; Gas

1989

Other Studies

5 other studies available for flurbiprofen and Gastrointestinal Hemorrhage

ArticleYear
Retrospective evaluation of the incidence of gastrointestinal bleeding in dogs receiving ophthalmic nonsteroidal anti-inflammatory drugs.
    Veterinary ophthalmology, 2023, Volume: 26, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dog Diseases; Dogs; Flurbiprofen; Gast

2023
Antiprostaglandin synthetase activity of nonsteroidal anti-inflammatory drugs and gastrointestinal micro-bleeding: a comparison of flurbiprofen with benoxaprofen.
    Annals of the rheumatic diseases, 1981, Volume: 40, Issue:5

    Topics: Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Benzoxazoles; Cyclooxygenase Inhibitors; Fece

1981
Blood-loss studies for new non-steroidal anti-inflammatory drugs.
    The Medical journal of Australia, 1982, Apr-17, Volume: 1, Issue:8

    Topics: Acetates; Anti-Inflammatory Agents; Chromium Radioisotopes; Erythrocytes; Flurbiprofen; Gastrointest

1982
Reduction of gastrointestinal injury in acute endotoxic shock by flurbiprofen nitroxybutylester.
    European journal of pharmacology, 1995, Jun-23, Volume: 280, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Flurbiprofen; Gastric Mucosa; Gast

1995
[Hemorrhagic angiodysplasia of the right colon after ingestion of non-steroidal anti-inflammatory agents].
    Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:11

    Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Colonic Diseases; Flurbiprofen; Gastrointestinal H

1994