Page last updated: 2024-10-27

flurbiprofen and Colorectal Neoplasms

flurbiprofen has been researched along with Colorectal Neoplasms in 6 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to reveal the appropriate timing for the intravenous administration of flurbiprofen axetil for preventing mesenteric traction syndrome (MTS), caused by prostacyclin release."9.24Therapeutic effects of flurbiprofen axetil on mesenteric traction syndrome: randomized clinical trial. ( Arai, H; Arita, M; Iwamoto, R; Shida, D; Suzuki, T; Tagawa, K; Takahashi, H, 2017)
"We explored the effects of flurbiprofen axetil on interleukin (IL)-2 and IL-6 levels in postoperative patients with colorectal cancer."7.81Effects of flurbiprofen axetil on postoperative serum IL-2 and IL-6 levels in patients with colorectal cancer. ( Duan, HX; Jiang, WW; Li, Y; Liao, YJ; Peng, P; Wang, QH; Xu, M; Zhang, PB, 2015)
"This study aimed to reveal the appropriate timing for the intravenous administration of flurbiprofen axetil for preventing mesenteric traction syndrome (MTS), caused by prostacyclin release."5.24Therapeutic effects of flurbiprofen axetil on mesenteric traction syndrome: randomized clinical trial. ( Arai, H; Arita, M; Iwamoto, R; Shida, D; Suzuki, T; Tagawa, K; Takahashi, H, 2017)
"We explored the effects of flurbiprofen axetil on interleukin (IL)-2 and IL-6 levels in postoperative patients with colorectal cancer."3.81Effects of flurbiprofen axetil on postoperative serum IL-2 and IL-6 levels in patients with colorectal cancer. ( Duan, HX; Jiang, WW; Li, Y; Liao, YJ; Peng, P; Wang, QH; Xu, M; Zhang, PB, 2015)
"The protection against colorectal cancer (CRC) by non-steroidal anti-inflammatory drugs (NSAIDs) is in part dependent on inhibition of cyclooxygenase (COX)."1.39Comparing the effects of COX and non-COX-inhibiting NSAIDs on enhancement of apoptosis and inhibition of aberrant crypt foci formation in a rat colorectal cancer model. ( Hu, Y; LE Leu, RK; Martin, JE; Young, GP, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takahashi, H2
Shida, D2
Tagawa, K2
Iwamoto, R1
Arita, M1
Arai, H1
Suzuki, T2
Martin, JE2
Young, GP2
LE Leu, RK2
Hu, Y2
Jiang, WW1
Wang, QH1
Peng, P1
Liao, YJ1
Duan, HX1
Xu, M1
Li, Y1
Zhang, PB1
Hughes-Fulford, M1
Boman, B1

Trials

2 trials available for flurbiprofen and Colorectal Neoplasms

ArticleYear
Therapeutic effects of flurbiprofen axetil on mesenteric traction syndrome: randomized clinical trial.
    BMC surgery, 2017, Aug-11, Volume: 17, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Colorec

2017
Hemodynamics of mesenteric traction syndrome measured by FloTrac sensor.
    Journal of clinical anesthesia, 2016, Volume: 30

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Colorectal Neoplas

2016

Other Studies

4 other studies available for flurbiprofen and Colorectal Neoplasms

ArticleYear
Comparing the effects of COX and non-COX-inhibiting NSAIDs on enhancement of apoptosis and inhibition of aberrant crypt foci formation in a rat colorectal cancer model.
    Anticancer research, 2013, Volume: 33, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoxymethane; Colorectal Neoplasms; Cyc

2013
Effects of flurbiprofen axetil on postoperative serum IL-2 and IL-6 levels in patients with colorectal cancer.
    Genetics and molecular research : GMR, 2015, Dec-09, Volume: 14, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colorectal Neoplasms; Enzyme-Linked Immunosorb

2015
R-flurbiprofen suppresses distal nonmucin-producing colorectal tumors in azoxymethane-treated rats, without suppressing eicosanoid production.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:6

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Colorectal Neoplasms; Dinoprostone; Disea

2010
Growth regulation of Gardner's syndrome colorectal cancer cells by NSAIDs.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Carcin

1997