flurbiprofen has been researched along with Colonic Neoplasms in 9 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Flurbiprofen, indomethacin and other NSAIDs stimulated 15-PGDH activity in colon cancer HT29 cells as well as in lung cancer A549 cells and glioblastoma T98G cells." | 4.87 | Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs). ( Chi, X; Tai, HH; Tong, M, 2011) |
| "We propose that, in a subset of colon cancer, upregulation of miR-493 during carcinogenesis prevents liver metastasis via the induction of cell death of metastasized cells." | 1.38 | miR-493 induction during carcinogenesis blocks metastatic settlement of colon cancer cells in liver. ( Ishiguro, T; Izumiya, M; Midorikawa, Y; Nakagama, H; Ohata, H; Okamoto, K; Sakai, H; Sato, A; Tsuchiya, N, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Korolkiewicz, R | 1 |
| Sein-Anand, J | 1 |
| Chi, X | 2 |
| Freeman, BM | 1 |
| Tong, M | 2 |
| Zhao, Y | 1 |
| Tai, HH | 2 |
| Okamoto, K | 1 |
| Ishiguro, T | 1 |
| Midorikawa, Y | 1 |
| Ohata, H | 1 |
| Izumiya, M | 1 |
| Tsuchiya, N | 1 |
| Sato, A | 1 |
| Sakai, H | 1 |
| Nakagama, H | 1 |
| Grösch, S | 2 |
| Tegeder, I | 1 |
| Schilling, K | 1 |
| Maier, TJ | 2 |
| Niederberger, E | 1 |
| Geisslinger, G | 2 |
| Janssen, A | 1 |
| Schmidt, R | 1 |
| Tutton, PJ | 1 |
| Barkla, DH | 1 |
| Wechter, WJ | 1 |
| Murray, ED | 1 |
| Kantoci, D | 1 |
| Quiggle, DD | 1 |
| Leipold, DD | 1 |
| Gibson, KM | 1 |
| McCracken, JD | 1 |
| Myers, C | 1 |
| Koki, A | 1 |
| Pamukcu, R | 1 |
| Wechter, W | 1 |
| Padley, RJ | 1 |
1 review available for flurbiprofen and Colonic Neoplasms
| Article | Year |
|---|---|
Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs).
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, | 2011 |
8 other studies available for flurbiprofen and Colonic Neoplasms
| Article | Year |
|---|---|
Mosapride and postoperative ileus.
Topics: Benzamides; Colectomy; Colonic Neoplasms; Cyclooxygenase Inhibitors; Drug Interactions; Flurbiprofen | 2009 |
15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colonic Neoplasms; Dose-Response Relationship, Drug; Down-R | 2009 |
miR-493 induction during carcinogenesis blocks metastatic settlement of colon cancer cells in liver.
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Colonic Neoplasms; Flurbiprofen; Gene Ex | 2012 |
Activation of c-Jun-N-terminal-kinase is crucial for the induction of a cell cycle arrest in human colon carcinoma cells caused by flurbiprofen enantiomers.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Caco-2 Cells; Carcinoma; Cell Cycle; Cell Cycle Protein | 2003 |
Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells.
Topics: Adenomatous Polyposis Coli Protein; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents | 2005 |
Influence of prostaglandin analogues on epithelial cell proliferation and xenograft growth.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Epithelium; Female; Flurbiprofen; Humans; Intestines; Ma | 1980 |
Treatment and survival study in the C57BL/6J-APC(Min)/+(Min) mouse with R-flurbiprofen.
Topics: Adenomatous Polyposis Coli; Alleles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colon; Coloni | 2000 |
Proapoptotic anti-inflammatory drugs.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Ce | 2001 |