Page last updated: 2024-10-27

flurbiprofen and Breast Neoplasms

flurbiprofen has been researched along with Breast Neoplasms in 11 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"Forty-women with primary breast cancer undergoing a modified radical mastectomy were randomized to receive postoperative analgesia with flurbiprofen axetil combined with fentanyl or fentanyl alone."9.20A Comparison of Fentanyl and Flurbiprofen Axetil on Serum VEGF-C, TNF-α, and IL-1ß Concentrations in Women Undergoing Surgery for Breast Cancer. ( Candiotti, KA; Castillo-Pedraza, C; Deng, H; Liu, W; Sun, H; Wang, M; Wang, Y; Wen, Y; Yang, J; Zhang, Y; Zhao, J; Zhou, Z, 2015)
"To investigate the effects of preemptive analgesia with flurbiprofen on the blood sugar and Interleukin-6 of patients after radical excision of breast cancer."9.14[Effects of preemptive analgesia with flurbiprofen on the blood sugar and interleukin-6 of patients after radical excision of breast cancer]. ( Chen, L; Dai, L; Fang, XM; Hu, SF; Jiang, W; Wu, XY; Zhang, YL, 2009)
"Two investigators enrolled 26 women with metastatic breast carcinoma in a six-week, double-blind, placebo-controlled, crossover study of flurbiprofen (Ansaid, Upjohn) and placebo."9.06Flurbiprofen for the treatment of bone pain in patients with metastatic breast cancer. ( Crampton, SL; Lamborn, KR; Lomen, PL; Samal, BA; Sattler, LP, 1986)
"To assess the modulating effects of a non-steroidal anti-inflammatory drug on chemotherapeutic agents, 183 patients with advanced breast cancer have been treated in a randomised study with flurbiprofen or placebo and adriamycin plus a vinca alkaloid."9.05The modulating effects of flurbiprofen on adriamycin plus vincristine or vindesine in the treatment of advanced breast cancer. ( Ashley, S; Clarke, S; Coombes, RC; Gibb, J; Gordon, C; Perez, DJ; Powles, TJ; Smith, IE; Vincent, MD, 1985)
"Forty-women with primary breast cancer undergoing a modified radical mastectomy were randomized to receive postoperative analgesia with flurbiprofen axetil combined with fentanyl or fentanyl alone."5.20A Comparison of Fentanyl and Flurbiprofen Axetil on Serum VEGF-C, TNF-α, and IL-1ß Concentrations in Women Undergoing Surgery for Breast Cancer. ( Candiotti, KA; Castillo-Pedraza, C; Deng, H; Liu, W; Sun, H; Wang, M; Wang, Y; Wen, Y; Yang, J; Zhang, Y; Zhao, J; Zhou, Z, 2015)
"To explore whether perioperative intravenous flurbiprofen axetil can reduce the incidence and intensity of chronic pain for breast cancer after surgical treatment."5.17Effect of perioperative intravenous flurbiprofen axetil on chronic postmastectomy pain. ( Liao, Q; Ouyang, W; Sun, M; Wen, L; Yan, X; Zhang, F, 2013)
"To investigate the effects of preemptive analgesia with flurbiprofen on the blood sugar and Interleukin-6 of patients after radical excision of breast cancer."5.14[Effects of preemptive analgesia with flurbiprofen on the blood sugar and interleukin-6 of patients after radical excision of breast cancer]. ( Chen, L; Dai, L; Fang, XM; Hu, SF; Jiang, W; Wu, XY; Zhang, YL, 2009)
"Two investigators enrolled 26 women with metastatic breast carcinoma in a six-week, double-blind, placebo-controlled, crossover study of flurbiprofen (Ansaid, Upjohn) and placebo."5.06Flurbiprofen for the treatment of bone pain in patients with metastatic breast cancer. ( Crampton, SL; Lamborn, KR; Lomen, PL; Samal, BA; Sattler, LP, 1986)
"To assess the modulating effects of a non-steroidal anti-inflammatory drug on chemotherapeutic agents, 183 patients with advanced breast cancer have been treated in a randomised study with flurbiprofen or placebo and adriamycin plus a vinca alkaloid."5.05The modulating effects of flurbiprofen on adriamycin plus vincristine or vindesine in the treatment of advanced breast cancer. ( Ashley, S; Clarke, S; Coombes, RC; Gibb, J; Gordon, C; Perez, DJ; Powles, TJ; Smith, IE; Vincent, MD, 1985)
"Previous studies have shown that the prostaglandin synthesis inhibitor indomethacin reduced osteolysis produced by the experimental VX2 carcinoma, probably by inhibiting the stimulation of osteoclasts by prostaglandin E2."3.66The effect of prostaglandin synthesis inhibitors and diphosphonates on tumour-mediated osteolysis. ( Galasko, CS; Lacey, E; Rushton, S; Samuel, AW, 1980)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's2 (18.18)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Predarska, I2
Saoud, M2
Morgan, I2
Eichhorn, T1
Kaluđerović, GN2
Hey-Hawkins, E2
Lönnecke, P1
Sun, M1
Liao, Q1
Wen, L1
Yan, X1
Zhang, F1
Ouyang, W1
Wen, Y1
Wang, M1
Yang, J1
Wang, Y1
Sun, H1
Zhao, J1
Liu, W1
Zhou, Z1
Deng, H1
Castillo-Pedraza, C1
Zhang, Y1
Candiotti, KA1
Hu, SF1
Zhang, YL1
Jiang, W1
Wu, XY1
Dai, L1
Chen, L1
Fang, XM1
Twycross, RG1
Galasko, CS1
Samuel, AW1
Rushton, S1
Lacey, E1
Tjandrawinata, RR1
Dahiya, R1
Hughes-Fulford, M1
Coombes, RC2
Neville, AM1
Gazet, JC1
Ford, HT1
Nash, AG1
Baker, JW1
Powles, JT1
Lomen, PL1
Samal, BA1
Lamborn, KR1
Sattler, LP1
Crampton, SL1
Perez, DJ1
Powles, TJ1
Smith, IE1
Vincent, MD1
Ashley, S1
Gordon, C1
Gibb, J1
Clarke, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison Study of a Low-Fat Diet Supplemented With Fish Oil and a Standard Western Diet in Individuals With Prostate Cancer[NCT00798876]56 participants (Actual)Interventional2001-12-18Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for flurbiprofen and Breast Neoplasms

ArticleYear
Effect of perioperative intravenous flurbiprofen axetil on chronic postmastectomy pain.
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2013, Volume: 38, Issue:7

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Chronic Disease; Double-Blin

2013
A Comparison of Fentanyl and Flurbiprofen Axetil on Serum VEGF-C, TNF-α, and IL-1ß Concentrations in Women Undergoing Surgery for Breast Cancer.
    Pain practice : the official journal of World Institute of Pain, 2015, Volume: 15, Issue:6

    Topics: Adult; Aged; Analgesics; Breast Neoplasms; Drug Therapy, Combination; Female; Fentanyl; Flurbiprofen

2015
[Effects of preemptive analgesia with flurbiprofen on the blood sugar and interleukin-6 of patients after radical excision of breast cancer].
    Zhonghua yi xue za zhi, 2009, Oct-27, Volume: 89, Issue:39

    Topics: Adult; Aged; Analgesia; Blood Glucose; Breast Neoplasms; Female; Flurbiprofen; Humans; Interleukin-6

2009
Flurbiprofen for the treatment of bone pain in patients with metastatic breast cancer.
    The American journal of medicine, 1986, Mar-24, Volume: 80, Issue:3A

    Topics: Adult; Aged; Bone and Bones; Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Double-Blind Met

1986
The modulating effects of flurbiprofen on adriamycin plus vincristine or vindesine in the treatment of advanced breast cancer.
    Cancer chemotherapy and pharmacology, 1985, Volume: 15, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as To

1985

Other Studies

6 other studies available for flurbiprofen and Breast Neoplasms

ArticleYear
Cisplatin-cyclooxygenase inhibitor conjugates, free and immobilised in mesoporous silica SBA-15, prove highly potent against triple-negative MDA-MB-468 breast cancer cell line.
    Dalton transactions (Cambridge, England : 2003), 2022, Jan-17, Volume: 51, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Cyclooxygenase

2022
Triphenyltin(IV) Carboxylates with Exceptionally High Cytotoxicity against Different Breast Cancer Cell Lines.
    Biomolecules, 2023, 03-26, Volume: 13, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Carboxylic Acids; Cell Line, Tumor; Female; Flurbiprofen; H

2023
Pruritus and pain in en cuirass breast cancer.
    Lancet (London, England), 1981, Sep-26, Volume: 2, Issue:8248

    Topics: Aged; Breast Neoplasms; Female; Flurbiprofen; Humans; Pain; Pruritus

1981
The effect of prostaglandin synthesis inhibitors and diphosphonates on tumour-mediated osteolysis.
    The British journal of surgery, 1980, Volume: 67, Issue:7

    Topics: Animals; Bone Resorption; Breast Neoplasms; Culture Techniques; Diphosphonates; Flurbiprofen; Humans

1980
Induction of cyclo-oxygenase-2 mRNA by prostaglandin E2 in human prostatic carcinoma cells.
    British journal of cancer, 1997, Volume: 75, Issue:8

    Topics: 16,16-Dimethylprostaglandin E2; Anti-Ulcer Agents; Breast Neoplasms; Cell Count; Cell Division; Cycl

1997
Agents affecting osteolysis in patients with breast cancer.
    Cancer chemotherapy and pharmacology, 1979, Volume: 3, Issue:1

    Topics: Anti-Inflammatory Agents; Aspirin; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcitonin; Fe

1979