flurbiprofen has been researched along with Brain Inflammation in 8 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated changes in the expression of adenosine type-2B (A2B) receptors and a related intracellular second messenger during chronic brain inflammation and following treatment with the non-steroidal anti-inflammatory drug flurbiprofen and its nitric oxide (NO)-donating derivative, HCT1026." | 3.72 | The influence of brain inflammation upon neuronal adenosine A2B receptors. ( Hauss-Wegrzyniak, B; McGann, K; Rosi, S; Wenk, GL, 2003) |
| " The current study investigated the ability of a nitric oxide (NO)-donating derivative of the nonsteroidal anti-inflammatory drug (NSAID) flurbiprofen, HCT1026, to reduce brain inflammation in young rats." | 3.71 | A nitric oxide-donating flurbiprofen derivative reduces neuroinflammation without interacting with galantamine in the rat. ( Hauss-Wegrzyniak, B; McGann, K; Rosi, S; Wenk, GL, 2002) |
| "Sham treatment and flurbiprofen treatment did not affect Aβ pathology, and a low dose HCT 1026 (10 mg/kg; a nitric oxide-donating flurbiprofen analog that has additional useful properties, including a remarkable gastrointestinal safety) did not affect pathology either, however a higher dose of HCT 1026 (30 mg/kg) did reduce the Aβ load." | 1.37 | Transgenic AD model mice, effects of potential anti-AD treatments on inflammation, and pathology. ( Kadish, I; Miettinen, P; van Groen, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (87.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Groen, T | 1 |
| Miettinen, P | 1 |
| Kadish, I | 1 |
| Wenk, GL | 2 |
| Rosi, S | 2 |
| McGann, K | 2 |
| Hauss-Wegrzyniak, B | 2 |
| Wilcock, DM | 1 |
| Munireddy, SK | 1 |
| Rosenthal, A | 1 |
| Ugen, KE | 1 |
| Gordon, MN | 1 |
| Morgan, D | 1 |
| Bernardo, A | 1 |
| Gasparini, L | 1 |
| Ongini, E | 1 |
| Minghetti, L | 2 |
| Kukar, T | 1 |
| Prescott, S | 1 |
| Eriksen, JL | 1 |
| Holloway, V | 1 |
| Murphy, MP | 1 |
| Koo, EH | 1 |
| Golde, TE | 1 |
| Nicolle, MM | 1 |
| Prosperi, C | 1 |
| Scali, C | 1 |
| Pepeu, G | 1 |
| Casamenti, F | 1 |
| Ajmone-Cat, MA | 1 |
| Nicolini, A | 1 |
8 other studies available for flurbiprofen and Brain Inflammation
| Article | Year |
|---|---|
Transgenic AD model mice, effects of potential anti-AD treatments on inflammation, and pathology.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Anti-Infl | 2011 |
A nitric oxide-donating flurbiprofen derivative reduces neuroinflammation without interacting with galantamine in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Brain; Cholinesterase Inhibitors; D | 2002 |
The influence of brain inflammation upon neuronal adenosine A2B receptors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Disease Models, Animal; Encephali | 2003 |
Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Antibodies; Brain; Dexa | 2004 |
Dynamic regulation of microglial functions by the non-steroidal anti-inflammatory drug NCX 2216: implications for chronic treatments of neurodegenerative diseases.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cells, Cultured; Dinopros | 2006 |
Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cyclooxyge | 2007 |
NO-flurbiprofen attenuates excitotoxin-induced brain inflammation, and releases nitric oxide in the brain.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Encephalitis; Excitatory Amino Acid Agonist | 2001 |
Differential effects of the nonsteroidal antiinflammatory drug flurbiprofen and its nitric oxide-releasing derivative, nitroflurbiprofen, on prostaglandin E(2), interleukin-1beta, and nitric oxide synthesis by activated microglia.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cell Survival; Cells, Cul | 2001 |