flurbiprofen has been researched along with Becker Muscular Dystrophy in 2 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In patients with Duchenne muscular dystrophy (DMD) and the standard mdx mouse model of DMD, dystrophin deficiency causes loss of neuronal nitric oxide synthase (nNOSĪ¼) from the sarcolemma, producing functional ischemia when the muscles are exercised." | 1.38 | Treatment with a nitric oxide-donating NSAID alleviates functional muscle ischemia in the mouse model of Duchenne muscular dystrophy. ( De Nardi, C; Monopoli, A; Ongini, E; Thomas, GD; Victor, RG; Ye, J, 2012) |
| "Duchenne muscular dystrophy is a relatively common disease that affects skeletal muscle, leading to progressive paralysis and death." | 1.34 | Nitric oxide release combined with nonsteroidal antiinflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy. ( Bottinelli, R; Brunelli, S; Clementi, E; Cossu, G; Covarello, D; D'Antona, G; Galvez, BG; Innocenzi, A; Monopoli, A; Ongini, E; Perrotta, C; Sanvito, F; Sciorati, C, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomas, GD | 1 |
| Ye, J | 1 |
| De Nardi, C | 1 |
| Monopoli, A | 2 |
| Ongini, E | 2 |
| Victor, RG | 1 |
| Brunelli, S | 1 |
| Sciorati, C | 1 |
| D'Antona, G | 1 |
| Innocenzi, A | 1 |
| Covarello, D | 1 |
| Galvez, BG | 1 |
| Perrotta, C | 1 |
| Sanvito, F | 1 |
| Bottinelli, R | 1 |
| Cossu, G | 1 |
| Clementi, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Renal Ageing-sarcopenia Network: a Combined Genetic, Immunological and Psychological Approach to Dissect Frailty[NCT04630132] | 1,500 participants (Anticipated) | Observational | 2017-03-25 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for flurbiprofen and Becker Muscular Dystrophy
| Article | Year |
|---|---|
Treatment with a nitric oxide-donating NSAID alleviates functional muscle ischemia in the mouse model of Duchenne muscular dystrophy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Disease Models, Animal; F | 2012 |
Nitric oxide release combined with nonsteroidal antiinflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Combined Modality Therapy; Creatine Kin | 2007 |