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flurbiprofen and Ankylosing Spondylarthritis

flurbiprofen has been researched along with Ankylosing Spondylarthritis in 13 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Research Excerpts

ExcerptRelevanceReference
"Flurbiprofen, a phenylalkanoic acid derivative, is a non-steroidal anti-inflammatory, antipyretic, analgesic agent advocated for use in rheumatoid arthritis, degenerative joint disease, ankylosing spondylitis and allied conditions."8.76Flurbiprofen: a review of its pharmacological properties and therapeutic use in rheumatic diseases. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1979)
"The safety of flurbiprofen (Ansaid, Upjohn) was assessed after pooling data on kidney and liver function collected from nine separate phase III clinical trials involving 1,677 patients (941 receiving flurbiprofen and 736 receiving comparison drugs) with ankylosing spondylitis, osteoarthritis, or rheumatoid arthritis."7.67Safety of flurbiprofen in the treatment of ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis. A summary of liver and kidney assay data. ( Lamborn, KR; Lomen, PL; Turner, LF, 1986)
"Flurbiprofen, a phenylalkanoic acid derivative, is a non-steroidal anti-inflammatory, antipyretic, analgesic agent advocated for use in rheumatoid arthritis, degenerative joint disease, ankylosing spondylitis and allied conditions."4.76Flurbiprofen: a review of its pharmacological properties and therapeutic use in rheumatic diseases. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1979)
" Two hundred patients presenting with classic rheumatic diseases (osteoarthritis, n = 50; rheumatoid arthritis, n = 130; ankylosing spondylitis, n = 20) were given a daily dose of 200 mg sustained-release flurbiprofen (flurbiprofen SR)."3.70Six-month prospective study to monitor the treatment of rheumatic diseases with sustained-release flurbiprofen. ( Miceková, D; Rovenský, J, 2000)
"The safety of flurbiprofen (Ansaid, Upjohn) was assessed after pooling data on kidney and liver function collected from nine separate phase III clinical trials involving 1,677 patients (941 receiving flurbiprofen and 736 receiving comparison drugs) with ankylosing spondylitis, osteoarthritis, or rheumatoid arthritis."3.67Safety of flurbiprofen in the treatment of ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis. A summary of liver and kidney assay data. ( Lamborn, KR; Lomen, PL; Turner, LF, 1986)
"Improvement of patients in all groups reached statistical significance after 1 month's treatment and remained significant at 12 months."2.66A long-term study of flurbiprofen in rheumatological disorders: III. Other articular conditions. ( Busson, M, 1986)
"Flurbiprofen appears to be an excellent alternative to phenylbutazone in the management of patients with ankylosing spondylitis."2.66Flurbiprofen in the treatment of ankylosing spondylitis. A comparison with phenylbutazone. ( Brinn, EL; Lamborn, KR; Lomen, PL; Sattler, LP; Turner, LF, 1986)
"Flurbiprofen is an excellent treatment for the control of pain and inflammation in patients with ankylosing spondylitis."2.66Flurbiprofen in the treatment of ankylosing spondylitis. A comparison with indomethacin. ( Brinn, EL; Lamborn, KR; Lomen, PL; Turner, LF, 1986)
"The pharmacokinetic profile of 200 mg sustained-release flurbiprofen capsules was compared in nine elderly (mean age 84."1.28A multiple dose pharmacokinetic and tolerance study of once daily 200 mg sustained-release flurbiprofen capsules in young and very elderly patients. ( Bird, A; Hamdy, RC; Hill, J; Hind, ID; Le Gallez, P, 1990)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burry, HC1
Siebers, R1
Rovenský, J1
Miceková, D1
Good, A1
Mena, H1
Doury, P1
Pattin, S1
Mena, HR2
Willkens, RF1
Good, AE1
Brogden, RN1
Heel, RC1
Speight, TM1
Avery, GS1
Hamdy, RC1
Bird, A1
Le Gallez, P1
Hill, J1
Hind, ID1
Busson, M1
Sigidin, IaA1
Murav'ev, IuV1
Lomen, PL3
Turner, LF3
Lamborn, KR3
Brinn, EL2
Sattler, LP1

Reviews

1 review available for flurbiprofen and Ankylosing Spondylarthritis

ArticleYear
Flurbiprofen: a review of its pharmacological properties and therapeutic use in rheumatic diseases.
    Drugs, 1979, Volume: 18, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Interactions; Flurbipr

1979

Trials

9 trials available for flurbiprofen and Ankylosing Spondylarthritis

ArticleYear
A comparison of flurbiprofen with naproxen in ankylosing spondylitis.
    The New Zealand medical journal, 1980, Oct-22, Volume: 92, Issue:670

    Topics: Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Gastrointestinal Diseases; Huma

1980
Treatment of ankylosing spondylitis with flurbiprofen and indomethacin.
    Current medical research and opinion, 1977, Volume: 5, Issue:1

    Topics: Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Indomethacin; Male; Pal

1977
Comparative study of the effectiveness of flurbiprofen given twice or 3-times daily.
    Current medical research and opinion, 1977, Volume: 5, Issue:1

    Topics: Adult; Aged; Drug Administration Schedule; Female; Flurbiprofen; Hip Joint; Humans; Male; Middle Age

1977
Treatment of ankylosing spondylitis with flurbiprofen or phenylbutazone.
    European journal of clinical pharmacology, 1977, Apr-20, Volume: 11, Issue:4

    Topics: Clinical Trials as Topic; Drug Evaluation; Female; Flurbiprofen; Humans; Male; Phenylbutazone; Propi

1977
Management of ankylosing spondylitis with flurbiprofen or indomethacin.
    Southern medical journal, 1977, Volume: 70, Issue:8

    Topics: Adult; Clinical Trials as Topic; Drug Tolerance; Flurbiprofen; Humans; Indomethacin; Propionates; Sp

1977
A long-term study of flurbiprofen in rheumatological disorders: III. Other articular conditions.
    The Journal of international medical research, 1986, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Arthritis; Child; Clinical Trials as Topic; Drug Therapy, Combination; Fema

1986
[Experience with using a new antirheumatic drug flugalin].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:8

    Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Flurbiprofen; Follow-Up Studie

1985
Flurbiprofen in the treatment of ankylosing spondylitis. A comparison with phenylbutazone.
    The American journal of medicine, 1986, Mar-24, Volume: 80, Issue:3A

    Topics: Adolescent; Adult; Drug Evaluation; Female; Flurbiprofen; Humans; Male; Middle Aged; Pain; Phenylbut

1986
Flurbiprofen in the treatment of ankylosing spondylitis. A comparison with indomethacin.
    The American journal of medicine, 1986, Mar-24, Volume: 80, Issue:3A

    Topics: Adolescent; Adult; Drug Evaluation; Female; Flurbiprofen; Humans; Indomethacin; Male; Middle Aged; P

1986

Other Studies

3 other studies available for flurbiprofen and Ankylosing Spondylarthritis

ArticleYear
Six-month prospective study to monitor the treatment of rheumatic diseases with sustained-release flurbiprofen.
    Drugs under experimental and clinical research, 2000, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Delayed-Act

2000
A multiple dose pharmacokinetic and tolerance study of once daily 200 mg sustained-release flurbiprofen capsules in young and very elderly patients.
    European journal of clinical pharmacology, 1990, Volume: 39, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arthritis, Rheumatoid; Capsules; Delayed-Action Preparations;

1990
Safety of flurbiprofen in the treatment of ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis. A summary of liver and kidney assay data.
    The American journal of medicine, 1986, Mar-24, Volume: 80, Issue:3A

    Topics: Alanine Transaminase; Alkaline Phosphatase; Arthritis, Rheumatoid; Aspartate Aminotransferases; Aspi

1986