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flurbiprofen and Amyloidosis

flurbiprofen has been researched along with Amyloidosis in 3 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.

Research Excerpts

ExcerptRelevanceReference
"Flurbiprofen (1) analogues were obtained with enhanced anti-inflammatory and antiamyloidogenic properties compared to 1, however, esterification led to elevated Aβ(1-42) levels."1.37Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates. ( Abdul-Hay, S; Qin, Z; Schiefer, IT; Thatcher, GR; Vanni, M; Wang, H, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schiefer, IT1
Abdul-Hay, S1
Wang, H1
Vanni, M1
Qin, Z1
Thatcher, GR1
Qiang, L1
Guan, Y1
Li, X1
Liu, L1
Mu, Y1
Sugano, A1
Takaoka, Y1
Sakaeda, T1
Imbimbo, BP1
Yamamura, KI1
Jin, S1
Li, Z1
De Lorenzi, E1
Galbusera, C1
Bellotti, V1
Mangione, P1
Massolini, G1
Tabolotti, E1
Andreola, A1
Caccialanza, G1

Trials

1 trial available for flurbiprofen and Amyloidosis

ArticleYear
CSP-1103 (CHF5074) stabilizes human transthyretin in healthy human subjects.
    Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 2017, Volume: 24, Issue:1

    Topics: Amyloidosis; Cyclopropanes; Flurbiprofen; Genetic Diseases, Inborn; Humans; Prealbumin; Thyroxine

2017

Other Studies

2 other studies available for flurbiprofen and Amyloidosis

ArticleYear
Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates.
    Journal of medicinal chemistry, 2011, Apr-14, Volume: 54, Issue:7

    Topics: Amyloid beta-Peptides; Amyloidosis; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non

2011
Affinity capillary electrophoresis is a powerful tool to identify transthyretin binding drugs for potential therapeutic use in amyloidosis.
    Electrophoresis, 2000, Volume: 21, Issue:15

    Topics: Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Electrophoresis, Capillary; Flu

2000