flurbiprofen has been researched along with Amyloidosis in 3 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flurbiprofen (1) analogues were obtained with enhanced anti-inflammatory and antiamyloidogenic properties compared to 1, however, esterification led to elevated Aβ(1-42) levels." | 1.37 | Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates. ( Abdul-Hay, S; Qin, Z; Schiefer, IT; Thatcher, GR; Vanni, M; Wang, H, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schiefer, IT | 1 |
| Abdul-Hay, S | 1 |
| Wang, H | 1 |
| Vanni, M | 1 |
| Qin, Z | 1 |
| Thatcher, GR | 1 |
| Qiang, L | 1 |
| Guan, Y | 1 |
| Li, X | 1 |
| Liu, L | 1 |
| Mu, Y | 1 |
| Sugano, A | 1 |
| Takaoka, Y | 1 |
| Sakaeda, T | 1 |
| Imbimbo, BP | 1 |
| Yamamura, KI | 1 |
| Jin, S | 1 |
| Li, Z | 1 |
| De Lorenzi, E | 1 |
| Galbusera, C | 1 |
| Bellotti, V | 1 |
| Mangione, P | 1 |
| Massolini, G | 1 |
| Tabolotti, E | 1 |
| Andreola, A | 1 |
| Caccialanza, G | 1 |
1 trial available for flurbiprofen and Amyloidosis
| Article | Year |
|---|---|
CSP-1103 (CHF5074) stabilizes human transthyretin in healthy human subjects.
Topics: Amyloidosis; Cyclopropanes; Flurbiprofen; Genetic Diseases, Inborn; Humans; Prealbumin; Thyroxine | 2017 |
2 other studies available for flurbiprofen and Amyloidosis
| Article | Year |
|---|---|
Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates.
Topics: Amyloid beta-Peptides; Amyloidosis; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non | 2011 |
Affinity capillary electrophoresis is a powerful tool to identify transthyretin binding drugs for potential therapeutic use in amyloidosis.
Topics: Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Electrophoresis, Capillary; Flu | 2000 |