Page last updated: 2024-10-27

flurbiprofen and Alloxan Diabetes

flurbiprofen has been researched along with Alloxan Diabetes in 6 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Research Excerpts

ExcerptRelevanceReference
"Flurbiprofen treatment of ND rats replicated many of the biochemical and physiological abnormalities of EDN, i."1.31Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration. ( Greene, DA; Larkin, D; Li, F; Marinescu, V; Pop-Busui, R; Stevens, MJ; Sullivan, K; Van Huysen, C, 2002)
"Flurbiprofen co-treatment markedly attenuated these actions of pentoxifylline on nerve conduction and blood flow whereas NG-nitro-L-arginine was without effect."1.31Pentoxifylline effects on nerve conduction velocity and blood flow in diabetic rats. ( Cameron, NE; Cotter, MA; Flint, H, 2000)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pop-Busui, R1
Marinescu, V1
Van Huysen, C1
Li, F1
Sullivan, K1
Greene, DA1
Larkin, D1
Stevens, MJ1
Dines, KC3
Cameron, NE5
Cotter, MA5
Maxfield, EK1
Robertson, S1
Cox, D1
Hohman, TC1
Flint, H1

Other Studies

6 other studies available for flurbiprofen and Alloxan Diabetes

ArticleYear
Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration.
    Diabetes, 2002, Volume: 51, Issue:8

    Topics: Acetylcarnitine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase

2002
Comparison of the effects of evening primrose oil and triglycerides containing gamma-linolenic acid on nerve conduction and blood flow in diabetic rats.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:1

    Topics: Animals; Diabetes Mellitus, Experimental; Dietary Fats, Unsaturated; Dose-Response Relationship, Dru

1995
Pharmacological manipulation of vascular endothelium function in non-diabetic and streptozotocin-diabetic rats: effects on nerve conduction, hypoxic resistance and endoneurial capillarization.
    Diabetologia, 1993, Volume: 36, Issue:6

    Topics: Animals; Arginine; Capillaries; Cell Hypoxia; Diabetes Mellitus, Experimental; Diabetic Neuropathies

1993
The effects of evening primrose oil on nerve function and capillarization in streptozotocin-diabetic rats: modulation by the cyclo-oxygenase inhibitor flurbiprofen.
    British journal of pharmacology, 1993, Volume: 109, Issue:4

    Topics: Action Potentials; Animals; Body Weight; Capillaries; Cyclooxygenase Inhibitors; Diabetes Mellitus,

1993
Interactions between essential fatty acid, prostanoid, polyol pathway and nitric oxide mechanisms in the neurovascular deficit of diabetic rats.
    Diabetologia, 1996, Volume: 39, Issue:2

    Topics: Acetanilides; Aldehyde Reductase; Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weigh

1996
Pentoxifylline effects on nerve conduction velocity and blood flow in diabetic rats.
    International journal of experimental diabetes research, 2000, Volume: 1, Issue:1

    Topics: Animals; Blood Glucose; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Flurbiprofen; Ma

2000