flurbiprofen has been researched along with Adjuvant Arthritis in 14 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preclinical Research The aim of this study was to evaluate the efficacy of multiple applications of S(+)-flurbiprofen plaster (SFPP), a novel Nonsteroidal anti-inflammatory drug (NSAID) patch, for the alleviation of inflammatory pain and edema in rat adjuvant-induced arthritis (AIA) model as compared to other NSAID patches." | 3.83 | Topical Anti-Inflammatory and Analgesic Effects of Multiple Applications of S(+)-Flurbiprofen Plaster (SFPP) in a Rat Adjuvant-Induced Arthritis Model. ( Hori, M; Ichihara, T; Kaku, S; Matsumoto, H; Mitani, A; Otsuka, N; Sekine, S; Sugimoto, M; Toda, Y, 2016) |
| "Rats with adjuvant arthritis were treated with either flurbiprofen (FBP) or tenidap (TDP), along with 4-dedimethylaminotetracycline (CMT-1), a potent MMP inhibitor." | 3.69 | Tenidap and flurbiprofen enhance uptake of matrix metalloproteinase inhibitor 4-dedimethylaminotetracycline in inflamed joints of adjuvant arthritic rats. ( Dieudonne, D; Golub, LM; Greenwald, RA; Koszulinski, R; Leung, MK; Moak, SA; Ramamurthy, NS, 1995) |
| "Male Lewis rats (n = 78) were randomly assigned to one of 10 groups, comprising controls, adjuvant arthritis (AA), and adjuvant arthritis with various combinations of 2 chemically modified, non-antimicrobial tetracycline derivatives (CMT3 or CMT8) with either of 2 nonsteroidal antiinflammatory agents (flurbiprofen or tenidap)." | 3.69 | Administration of systemic matrix metalloproteinase inhibitors maintains bone mechanical integrity in adjuvant arthritis. ( Golub, LM; Greenwald, RA; Leng, W; Moak, SA; Wohl, GR; Zernicke, RF, 1997) |
| "To determine the effect of arthritis on the disposition of flurbiprofen (FP) and its acyl glucuronide (FPG) as well as formation of covalent adducts with plasma protein, a pharmacokinetic study was carried out in adjuvant-induced arthritic (AA) rats." | 1.32 | Stereoselective pharmacokinetics of flurbiprofen and formation of covalent adducts with plasma protein in adjuvant-induced arthritic rats. ( Iwaki, M; Nagao, T; Tanino, T, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maryanoff, BE | 1 |
| Keeley, SL | 1 |
| Persico, FJ | 1 |
| Fukumoto, A | 1 |
| Tajima, K | 1 |
| Hori, M | 3 |
| Toda, Y | 3 |
| Kaku, S | 3 |
| Matsumoto, H | 3 |
| Sugimoto, M | 2 |
| Mitani, A | 2 |
| Ichihara, T | 2 |
| Sekine, S | 2 |
| Hirose, T | 1 |
| Endo, H | 1 |
| Futaki, N | 1 |
| Otsuka, N | 2 |
| Kawase, A | 1 |
| Ikuta, H | 1 |
| Uno, S | 1 |
| Yamamoto, K | 1 |
| Akitsu, N | 1 |
| Nagao, T | 2 |
| Iwaki, M | 2 |
| Kawadkar, J | 1 |
| Jain, R | 1 |
| Kishore, R | 1 |
| Pathak, A | 1 |
| Chauhan, MK | 1 |
| Tanino, T | 1 |
| Leung, MK | 1 |
| Greenwald, RA | 3 |
| Ramamurthy, NS | 2 |
| Moak, SA | 3 |
| Koszulinski, R | 1 |
| Dieudonne, D | 1 |
| Golub, LM | 3 |
| Uchida, S | 1 |
| Morishita, T | 1 |
| Ikeda, Y | 1 |
| Akashi, T | 1 |
| Zernicke, RF | 1 |
| Wohl, GR | 1 |
| Leng, W | 1 |
| Cannon, GW | 1 |
| Harper, DS | 1 |
| Goldberg, RL | 1 |
| Rubin, AS | 1 |
| Hunneyball, IM | 1 |
| Crossley, MJ | 1 |
| Spowage, M | 1 |
14 other studies available for flurbiprofen and Adjuvant Arthritis
| Article | Year |
|---|---|
Replacement of aromatic or heteroaromatic groups in nonsteroidal antiinflammatory agents with the ferrocene group.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Blood Platelets; Female; Ferrous Compoun | 1983 |
Analgesic effect of S (+)-flurbiprofen plaster in a rat model of knee arthritis: analysis of gait and synovial fluid prostaglandin E
Topics: Analgesics; Animals; Arthritis, Experimental; Dinoprostone; Disease Models, Animal; Dose-Response Re | 2018 |
Analgesic Effect of the Newly Developed S(+)-Flurbiprofen Plaster on Inflammatory Pain in a Rat Adjuvant-Induced Arthritis Model.
Topics: Administration, Topical; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Ex | 2016 |
Topical Anti-Inflammatory and Analgesic Effects of Multiple Applications of S(+)-Flurbiprofen Plaster (SFPP) in a Rat Adjuvant-Induced Arthritis Model.
Topics: Administration, Cutaneous; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, | 2016 |
Alteration in plasma protein binding properties of propranolol and flurbiprofen during development of adjuvant-induced arthritis in rats.
Topics: Alkaline Phosphatase; Animals; Arthritis, Experimental; Aspartate Aminotransferases; Blood Proteins; | 2013 |
Formulation and evaluation of flurbiprofen-loaded genipin cross-linked gelatin microspheres for intra-articular delivery.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Biocompatible Materials; | 2013 |
Stereoselective pharmacokinetics of flurbiprofen and formation of covalent adducts with plasma protein in adjuvant-induced arthritic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Bile; Blood Proteins; Cyt | 2003 |
Tenidap and flurbiprofen enhance uptake of matrix metalloproteinase inhibitor 4-dedimethylaminotetracycline in inflamed joints of adjuvant arthritic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Collagenases; Drug Synerg | 1995 |
Anti-inflammatory effect of flurbiprofen tape applied percutaneously to rats with adjuvant-induced arthritis.
Topics: Administration, Topical; Animals; Arthritis, Experimental; Body Weight; Flurbiprofen; Male; Rats; Ra | 1995 |
Administration of systemic matrix metalloproteinase inhibitors maintains bone mechanical integrity in adjuvant arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Body Weight; Cross-Linkin | 1997 |
Tetracyclines suppress matrix metalloproteinase activity in adjuvant arthritis and in combination with flurbiprofen, ameliorate bone damage.
Topics: Administration, Oral; Animals; Arthritis, Experimental; Bone and Bones; Cartilage, Articular; Collag | 1992 |
The effects of flurbiprofen on the passive transfer of adjuvant-induced arthritis.
Topics: Animals; Arthritis, Experimental; Flurbiprofen; Freund's Adjuvant; Immunization, Passive; Male; Rats | 1992 |
Serum hyaluronate as a marker for disease severity in the Lactobacillus casei model of arthritis in the rat.
Topics: Animals; Arthritis; Arthritis, Experimental; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; | 1989 |
Pharmacological studies of antigen-induced arthritis in BALB/c mice. I. Characterization of the arthritis and the effects of steroidal and non-steroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Dexamethasone; Female; Flurbi | 1986 |