Page last updated: 2024-10-27

flurbiprofen and Adenocarcinoma

flurbiprofen has been researched along with Adenocarcinoma in 9 studies

Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" Flurbiprofen, indomethacin and other NSAIDs stimulated 15-PGDH activity in colon cancer HT29 cells as well as in lung cancer A549 cells and glioblastoma T98G cells."4.87Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs). ( Chi, X; Tai, HH; Tong, M, 2011)
"Adenocarcinoma in Barrett's esophagus has been increasing in incidence at a rapid rate for more than two decades."1.31Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells. ( Beer, DG; Cryer, B; Shewmake, K; Souza, RF; Spechler, SJ, 2000)
" Flurbiprofen did not seem to alter the bioavailability of the chemotherapeutic agents."1.26Increased survival of cancer-bearing mice treated with inhibitors of prostaglandin synthesis alone or with chemotherapy. ( Bennett, A; Berstock, DA; Carroll, MA, 1982)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tai, HH1
Chi, X1
Tong, M1
Karmali, RA3
Bennett, A2
Berstock, DA2
Carroll, MA1
Tutton, PJ1
Barkla, DH1
Houghton, J1
Wechter, WJ1
Leipold, DD1
Murray, ED1
Quiggle, D1
McCracken, JD1
Barrios, RS1
Greenberg, NM1
Souza, RF1
Shewmake, K1
Beer, DG1
Cryer, B1
Spechler, SJ1
Lehnert, T1
Deschner, EE1
DeCosse, JJ1
Marsh, J1

Reviews

1 review available for flurbiprofen and Adenocarcinoma

ArticleYear
Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs).
    Prostaglandins & other lipid mediators, 2011, Volume: 96, Issue:1-4

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line,

2011

Other Studies

8 other studies available for flurbiprofen and Adenocarcinoma

ArticleYear
Growth inhibition and prostaglandin metabolism in the R3230AC mammary adenocarcinoma by reduced glutathione.
    Cancer biochemistry biophysics, 1984, Volume: 7, Issue:2

    Topics: Adenocarcinoma; Animals; Cyclooxygenase Inhibitors; Dinoprostone; Female; Flurbiprofen; Glutathione;

1984
Increased survival of cancer-bearing mice treated with inhibitors of prostaglandin synthesis alone or with chemotherapy.
    British journal of cancer, 1982, Volume: 45, Issue:5

    Topics: Adenocarcinoma; Animals; Biological Availability; Body Weight; Drug Therapy, Combination; Female; Fl

1982
Influence of prostaglandin analogues on epithelial cell proliferation and xenograft growth.
    British journal of cancer, 1980, Volume: 41, Issue:1

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Epithelium; Female; Flurbiprofen; Humans; Intestines; Ma

1980
Improved anticancer effect by combining cytotoxic drugs with an inhibitor of prostaglandin synthesis.
    Advances in prostaglandin and thromboxane research, 1980, Volume: 6

    Topics: Adenocarcinoma; Animals; Drug Evaluation, Preclinical; Female; Flurbiprofen; Mammary Neoplasms, Expe

1980
E-7869 (R-flurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse.
    Cancer research, 2000, Apr-15, Volume: 60, Issue:8

    Topics: Adenocarcinoma; Animals; Body Weight; Dietary Fats; Disease Models, Animal; Disease Progression; Flu

2000
Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells.
    Cancer research, 2000, Oct-15, Volume: 60, Issue:20

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Barrett Esophagus; Cell Division

2000
Effect of flurbiprofen and 16,16-dimethyl prostaglandin E2 on gastrointestinal tumorigenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats: glandular epithelium of stomach and duodenum.
    Cancer research, 1990, Jan-15, Volume: 50, Issue:2

    Topics: 16,16-Dimethylprostaglandin E2; Adenocarcinoma; Animals; Body Weight; Duodenal Neoplasms; Female; Fl

1990
Antitumor activity in a rat mammary adenocarcinoma: the effect of cyclooxygenase inhibitors and immunization against prostaglandin E2.
    Prostaglandins, leukotrienes, and medicine, 1985, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Animals; Antibodies; Antineoplastic Agents; Cell Line; Cyclooxygenase Inhibitors; Di

1985