flurazepam has been researched along with Sleep Wake Disorders in 30 studies
Flurazepam: A benzodiazepine derivative used mainly as a hypnotic.
flurazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a 2-(diethylamino)ethyl group, 2-fluorophenyl group and chloro group at positions 1, 5 and 7, respectively. It is a partial agonist of GABAA receptors and used for the treatment of insomnia.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flurazepam side effects were excessive drowsiness during daytime in 3 cases; irritability, 3 cases; nausea and vomiting, 2 cases, and were not correlated with age." | 2.65 | Evaluation of flurazepam and placebo on sleep disorders in childhood. ( Lefévre, AB; Reimão, R, 1982) |
| "In general, chronic insomniacs showed all degrees of daytime alertness regardless of nocturnal sleep parameters." | 2.37 | Issues in the diagnosis and treatment of insomnia. ( Carskadon, M; Dement, W; Seidel, W, 1984) |
| "The diagnosis and treatment of insomnia is a major clinical issue." | 2.36 | Rational basis for the use of sleeping pills. ( Dement, WC, 1983) |
| "Fifty-two male PTSD outpatients on stable combination treatment with SSRI and benzodiazepines, with persistent sleep disturbances not responding to prescription of zolpidem, flurazepam, nitrazepam, promazine, and levopromazine, were assessed for sleep disturbances improvements after prescription of quetiapine in the evening." | 1.72 | Quetiapine Add-On Therapy May Improve Persistent Sleep Disturbances in Patients with PTSD on Stabile Combined SSRI and Benzodiazepine Combination: A One-Group Pretest-Posttest Study. ( Karlović, D; Ljubičić Bistrović, I; Ljubičić, R; Matošić, A; Peitl, V; Vilibić, M; Vlatković, S; Živković, M, 2022) |
| " Possible explanations for the lower frequency of hypnotic use observed in this study as compared to the frequencies reported in the literature are discussed, as are possible hazards of high-dose and long-term use of hypnotics." | 1.27 | Survey of hypnotic drug use in nursing homes. ( James, DS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (90.00) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Vilibić, M | 1 |
| Peitl, V | 1 |
| Živković, M | 1 |
| Vlatković, S | 1 |
| Ljubičić Bistrović, I | 1 |
| Ljubičić, R | 1 |
| Matošić, A | 1 |
| Karlović, D | 1 |
| Verster, JC | 1 |
| Roth, T | 3 |
| Keighley, MR | 1 |
| Gannon, M | 1 |
| Warlow, J | 1 |
| Jenkins, CR | 1 |
| Gammon, RJ | 1 |
| Murphy, JE | 1 |
| Ankier, SI | 1 |
| Warburton, DM | 1 |
| Wesnes, K | 1 |
| Dement, WC | 2 |
| Dement, W | 1 |
| Seidel, W | 1 |
| Carskadon, M | 1 |
| Kamgar-Parsi, B | 1 |
| Wehr, TA | 1 |
| Gillin, JC | 1 |
| James, RT | 1 |
| Dean, BC | 1 |
| Seidel, WF | 1 |
| Roehrs, T | 2 |
| Zorick, F | 2 |
| Adam, K | 1 |
| Oswald, I | 2 |
| Reimão, R | 1 |
| Lefévre, AB | 1 |
| Brodersen, PE | 1 |
| Mikkelsen, BO | 1 |
| Viukari, M | 1 |
| Linnoila, M | 1 |
| Aalto, U | 1 |
| Singer, K | 1 |
| Lo, CW | 1 |
| Tam, YK | 1 |
| Church, MW | 1 |
| Johnson, LC | 1 |
| Miller, RR | 1 |
| Greenblatt, DJ | 1 |
| Henkes, H | 1 |
| Kubicki, S | 1 |
| Hansen, ML | 1 |
| Terstegge, K | 1 |
| Scholz, G | 1 |
| Ruhnke, M | 1 |
| Conway, W | 1 |
| Mendelson, WB | 1 |
| Martin, JV | 1 |
| Stephens, H | 1 |
| Giesen, H | 1 |
| James, SP | 1 |
| Soldatos, CR | 1 |
| Kales, A | 1 |
| Bixler, EO | 1 |
| Vela-Bueno, A | 1 |
| James, DS | 1 |
| Autera, C | 1 |
| Leickert, KH | 1 |
| Frolund, F | 1 |
| Sogliani, G | 1 |
| Preston, FS | 1 |
| Heimann, H | 1 |
| Schmocker, AM | 1 |
6 reviews available for flurazepam and Sleep Wake Disorders
| Article | Year |
|---|---|
Gender differences in highway driving performance after administration of sleep medication: a review of the literature.
Topics: Acetamides; Automobile Driving; Azabicyclo Compounds; Environment Design; Female; Flurazepam; Humans | 2012 |
Rational basis for the use of sleeping pills.
Topics: Anxiety; Chronic Disease; Flurazepam; Humans; Hypnotics and Sedatives; Kinetics; Sleep; Sleep Initia | 1983 |
Issues in the diagnosis and treatment of insomnia.
Topics: Chronic Disease; Flurazepam; Humans; Hypnotics and Sedatives; Psychomotor Performance; Respiration; | 1984 |
Pharmacology of benzodiazepine hypnotics.
Topics: Benzodiazepines; Flurazepam; Humans; Memory; Receptors, GABA-A; Sleep; Sleep Initiation and Maintena | 1992 |
Pharmacological effects of sedative-hypnotics, narcotic analgesics, and alcohol during sleep.
Topics: Adult; Aged; Anti-Anxiety Agents; Ethanol; Female; Flurazepam; Humans; Hypnotics and Sedatives; Male | 1985 |
Behavioral side effects of benzodiazepine hypnotics.
Topics: Amnesia; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Flurazepam; Humans; Hypnotics and Sedatives; | 1985 |
12 trials available for flurazepam and Sleep Wake Disorders
| Article | Year |
|---|---|
Evaluation of single-dose hypnotic treatment before elective operation.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; | 1980 |
A comparison of the hypnotic activity of loprazolam, flurazepam and placebo.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clinical Trials as Topic | 1984 |
A comparison of temazepam and flurazepam in terms of sleep quality and residual changes in activation and performance.
Topics: Adult; Anti-Anxiety Agents; Female; Flurazepam; Humans; Male; Psychomotor Performance; Reaction Time | 1984 |
Treatment of a 12-hour shift of sleep schedule with benzodiazepines.
Topics: Adult; Arousal; Benzodiazepines; Emotions; Female; Flurazepam; Humans; Male; Sleep; Sleep Wake Disor | 1984 |
Evaluation of flurazepam and placebo on sleep disorders in childhood.
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Female; Flurazepam; Humans; Infant; M | 1982 |
[Treatment of sleep disorders with flurazepam (Dalmadorm), nitrazepam (Mogadon), and allypropymal. A controlled clinical investigation].
Topics: Anti-Anxiety Agents; Barbiturates; Clinical Trials as Topic; Flurazepam; Humans; Nitrazepam; Sleep W | 1976 |
Efficacy and side effects of flurazepam, fosazepam, and nitrazepam as sleeping aids in psychogeriatric patients.
Topics: Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Diazepam; Drug Evaluation; Female; Flurazepam; | 1978 |
Comparative evaluation of hypnotic efficacy of flunitrazepam in psychiatric in-patients.
Topics: Adult; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Fe | 1978 |
Mood and performance of poor sleepers during repeated use of flurazepam.
Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Cognition; Double-Blind Method; Electroencepha | 1979 |
Effects of flurazepam on sleep, arousal threshold, and the perception of being asleep.
Topics: Adult; Arousal; Electroencephalography; Female; Flurazepam; Humans; Male; Perception; Sensory Thresh | 1988 |
[Flurazepam--a new soposfit drug].
Topics: Animals; Anti-Anxiety Agents; Clinical Trials as Topic; Dogs; Drug Evaluation; Female; Flurazepam; H | 1974 |
[Use of a new hypnotic agent in neuropsychiatry].
Topics: Adolescent; Adult; Aged; Benzodiazepinones; Clinical Trials as Topic; Female; Flurazepam; Humans; Hy | 1974 |
12 other studies available for flurazepam and Sleep Wake Disorders
| Article | Year |
|---|---|
Quetiapine Add-On Therapy May Improve Persistent Sleep Disturbances in Patients with PTSD on Stabile Combined SSRI and Benzodiazepine Combination: A One-Group Pretest-Posttest Study.
Topics: Antipsychotic Agents; Benzodiazepines; Flurazepam; Humans; Hypnotics and Sedatives; Male; Methotrime | 2022 |
Successful treatment of human non-24-hour sleep-wake syndrome.
Topics: Adult; Diazepam; Flurazepam; Humans; Male; Periodicity; Sleep Wake Disorders; Thyroxine; Vitamin B 1 | 1983 |
Reducing the risk: barbiturate substitution with a benzodiazepine.
Topics: Adult; Aged; Barbiturates; Female; Flurazepam; Humans; Male; Middle Aged; Risk; Sleep Wake Disorders | 1983 |
Effects of lormetazepam and of flurazepam on sleep.
Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Female; Flurazepam; Half-Life; Huma | 1984 |
A guide to the use of hypnotic drugs.
Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Drug Interactions; Flurazepam; | 1979 |
[The how and why of sedatives].
Topics: Female; Flurazepam; Humans; Hypnotics and Sedatives; Middle Aged; Personality; Sleep; Sleep Wake Dis | 1979 |
[Effects of flurazepam on disturbed sleep in patients with AIDS].
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Age Factors; Electroencephalography | 1989 |
Survey of hypnotic drug use in nursing homes.
Topics: Aged; Diphenhydramine; Drug Administration Schedule; Drug Prescriptions; Drug Utilization; Female; F | 1985 |
[Preparation with the flurazepam base. Study on tolerance and efficacy].
Topics: Ambulatory Care; Anti-Anxiety Agents; Drug Tolerance; Female; Flurazepam; Humans; Sleep Wake Disorde | 1974 |
[Flurazepam (Dalmadorm, Roche)].
Topics: Benzazepines; Fatigue; Flurazepam; Humans; Sleep Wake Disorders | 1974 |
Further sleep problems in airline pilots on world-wide schedules.
Topics: Adult; Aerospace Medicine; Age Factors; Barbiturates; Biological Clocks; Body Temperature; Fatigue; | 1973 |
[Sleep disorders, their origin and treatment].
Topics: Age Factors; Antidepressive Agents; Depression; Flurazepam; Humans; Intracranial Arteriosclerosis; M | 1974 |