flurazepam has been researched along with Chronic Illness in 16 studies
Flurazepam: A benzodiazepine derivative used mainly as a hypnotic.
flurazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a 2-(diethylamino)ethyl group, 2-fluorophenyl group and chloro group at positions 1, 5 and 7, respectively. It is a partial agonist of GABAA receptors and used for the treatment of insomnia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypnotic efficacy and safety of 3 weeks of daily doses of 2 mg lorazepam or 30 mg flurazepam were compared in a double-blind cross-over study in eight chronic insomniacs between the ages of 29 and 60 years." | 9.06 | Comparison of lorazepam and flurazepam as hypnotic agents in chronic insomniacs. ( Chang, H; McClure, DJ; Olah, A; Pecknold, JC; Walsh, J; Wilson, R, 1988) |
| " Oxazepam and flurazepam were effective in improving some polysomnographically defined measures of nocturnal sleep in 14 patients with chronic insomnia; flurazepam produced substantial daytime sleepiness and oxazepam did not." | 9.05 | Nighttime and daytime efficacy of flurazepam and oxazepam in chronic insomnia. ( Bliwise, D; Dement, W; Greenblatt, DJ; Seidel, W, 1984) |
| "Hypnotic efficacy and safety of 3 weeks of daily doses of 2 mg lorazepam or 30 mg flurazepam were compared in a double-blind cross-over study in eight chronic insomniacs between the ages of 29 and 60 years." | 5.06 | Comparison of lorazepam and flurazepam as hypnotic agents in chronic insomniacs. ( Chang, H; McClure, DJ; Olah, A; Pecknold, JC; Walsh, J; Wilson, R, 1988) |
| "The hypnotic effects of l-tryptophan (1 g), secobarbital (100 mg), and flurazepam (30 mg), relative to placebo, were evaluated in a sample of 54 outpatient chronic insomniacs with a major complaint of sleep maintenance insomnia." | 5.05 | Selectivity in response to L-tryptophan among insomniac subjects: a preliminary report. ( Hartmann, EL; Lindsley, JG; Mitchell, W, 1983) |
| " Oxazepam and flurazepam were effective in improving some polysomnographically defined measures of nocturnal sleep in 14 patients with chronic insomnia; flurazepam produced substantial daytime sleepiness and oxazepam did not." | 5.05 | Nighttime and daytime efficacy of flurazepam and oxazepam in chronic insomnia. ( Bliwise, D; Dement, W; Greenblatt, DJ; Seidel, W, 1984) |
| "Twelve volunteers with a complaint of chronic insomnia participated in a placebo-controlled, double-blind, crossover study of the effects of buspirone t." | 5.05 | Buspirone: an anxiolytic without sedative effect. ( Bliwise, NG; Cohen, SA; Dement, WC; Seidel, WF, 1985) |
| "A male patient with chronic insomnia experienced withdrawal symptoms when flurazepam (30 mg h." | 3.66 | Withdrawal symptoms after long-term treatment with therapeutic doses of flurazepam: a case report. ( Berlin, RM; Conell, LJ, 1983) |
| "Triazolam (0." | 2.64 | Comparative efficacy of triazolam, flurazepam and placebo in out-patients insomniacs. ( Bowen, AJ, 1978) |
| "In general, chronic insomniacs showed all degrees of daytime alertness regardless of nocturnal sleep parameters." | 2.37 | Issues in the diagnosis and treatment of insomnia. ( Carskadon, M; Dement, W; Seidel, W, 1984) |
| "The diagnosis and treatment of insomnia is a major clinical issue." | 2.36 | Rational basis for the use of sleeping pills. ( Dement, WC, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (81.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Conell, LJ | 2 |
| Berlin, RM | 2 |
| Lindsley, JG | 2 |
| Hartmann, EL | 1 |
| Mitchell, W | 1 |
| Dement, WC | 2 |
| Dement, W | 2 |
| Seidel, W | 2 |
| Carskadon, M | 1 |
| Hartmann, E | 1 |
| Spinweber, C | 1 |
| Bliwise, D | 1 |
| Greenblatt, DJ | 1 |
| Geddes, DM | 1 |
| Rudolf, M | 1 |
| Saunders, KB | 1 |
| Bowen, AJ | 1 |
| Walsh, JK | 1 |
| Mahowald, MW | 1 |
| Johnson, LC | 2 |
| Chernik, DA | 2 |
| Sateia, MJ | 1 |
| Chen, D | 1 |
| Ellinwood, E | 1 |
| Hauri, P | 1 |
| Judd, LL | 1 |
| Kripke, DF | 1 |
| Linnoila, M | 1 |
| Moskowitz, H | 1 |
| Roth, T | 1 |
| Seidel, WF | 1 |
| Cohen, SA | 1 |
| Bliwise, NG | 1 |
| McClure, DJ | 1 |
| Walsh, J | 1 |
| Chang, H | 1 |
| Olah, A | 1 |
| Wilson, R | 1 |
| Pecknold, JC | 1 |
| Kales, A | 1 |
| Bixler, EO | 1 |
| Tan, TL | 1 |
| Scharf, MB | 1 |
| Kales, JD | 1 |
| Hussey, HH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Oxycodone on Individuals Taking an SSRI[NCT05730062] | Phase 1 | 55 participants (Anticipated) | Interventional | 2023-03-15 | Not yet recruiting | ||
| Clinical Study to Investigate the Effect of the Combination of Psychotropic Drugs and an Opioid on Ventilation[NCT04310579] | Phase 1 | 55 participants (Actual) | Interventional | 2020-06-15 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for flurazepam and Chronic Illness
| Article | Year |
|---|---|
Rational basis for the use of sleeping pills.
Topics: Anxiety; Chronic Disease; Flurazepam; Humans; Hypnotics and Sedatives; Kinetics; Sleep; Sleep Initia | 1983 |
Issues in the diagnosis and treatment of insomnia.
Topics: Chronic Disease; Flurazepam; Humans; Hypnotics and Sedatives; Psychomotor Performance; Respiration; | 1984 |
Sleep, performance, and plasma levels in chronic insomniacs during 14-day use of flurazepam and midazolam: an introduction.
Topics: Chronic Disease; Double-Blind Method; Flurazepam; Humans; Long-Term Care; Midazolam; Psychomotor Per | 1990 |
8 trials available for flurazepam and Chronic Illness
| Article | Year |
|---|---|
Selectivity in response to L-tryptophan among insomniac subjects: a preliminary report.
Topics: Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Female; Flurazepam; Humans; Hypn | 1983 |
Chronic insomnia: effects of tryptophan, flurazepam, secobarbital, and placebo.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Female; Flurazepam; Humans; Male; Placebos; Secoba | 1983 |
Nighttime and daytime efficacy of flurazepam and oxazepam in chronic insomnia.
Topics: Chronic Disease; Circadian Rhythm; Electroencephalography; Electromyography; Electrooculography; Flu | 1984 |
Comparative efficacy of triazolam, flurazepam and placebo in out-patients insomniacs.
Topics: Adult; Anti-Anxiety Agents; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; | 1978 |
Sleep, performance, and plasma levels in chronic insomniacs during 14-day use of flurazepam and midazolam: an introduction.
Topics: Chronic Disease; Double-Blind Method; Flurazepam; Humans; Long-Term Care; Midazolam; Psychomotor Per | 1990 |
A multicenter study of sleep, performance, and plasma levels in chronic insomniacs during 14-day use of flurazepam and midazolam: executive summary.
Topics: Adult; Affect; Arousal; Chronic Disease; Double-Blind Method; Flurazepam; Humans; Midazolam; Psychom | 1990 |
Buspirone: an anxiolytic without sedative effect.
Topics: Adult; Anti-Anxiety Agents; Buspirone; Chronic Disease; Clinical Trials as Topic; Double-Blind Metho | 1985 |
Comparison of lorazepam and flurazepam as hypnotic agents in chronic insomniacs.
Topics: Adult; Arousal; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Electroencephalograp | 1988 |
6 other studies available for flurazepam and Chronic Illness
| Article | Year |
|---|---|
Withdrawal after substitution of a short-acting for a long-acting benzodiazepine.
Topics: Anti-Anxiety Agents; Anxiety; Chronic Disease; Delayed-Action Preparations; Diazepam; Flurazepam; Ha | 1983 |
Withdrawal symptoms after long-term treatment with therapeutic doses of flurazepam: a case report.
Topics: Adult; Chronic Disease; Flurazepam; Humans; Male; Sleep Initiation and Maintenance Disorders; Substa | 1983 |
Effect of nitrazepam and flurazepam on the ventilatory response to carbon dioxide.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Bronchitis; Carbon Dioxide; Chronic Disease; Depressio | 1976 |
Effect of nitrazepam and flurazepam on the ventilatory response to carbon dioxide.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Bronchitis; Carbon Dioxide; Chronic Disease; Depressio | 1976 |
Effect of nitrazepam and flurazepam on the ventilatory response to carbon dioxide.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Bronchitis; Carbon Dioxide; Chronic Disease; Depressio | 1976 |
Effect of nitrazepam and flurazepam on the ventilatory response to carbon dioxide.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Bronchitis; Carbon Dioxide; Chronic Disease; Depressio | 1976 |
Avoiding the blanket approach to insomnia. Targeted therapy for specific causes.
Topics: Anti-Anxiety Agents; Benzodiazepines; Chronic Disease; Diagnosis, Differential; Estazolam; Flurazepa | 1991 |
Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence.
Topics: Adult; Age Factors; Aged; Amobarbital; Chloral Hydrate; Chronic Disease; Dreams; Drug Therapy, Combi | 1974 |
Editorial: Insomnia.
Topics: Apnea; Chronic Disease; Flurazepam; Humans; Hypnotics and Sedatives; Iatrogenic Disease; Male; Middl | 1974 |