flurazepam has been researched along with Chemical Dependence in 23 studies
Flurazepam: A benzodiazepine derivative used mainly as a hypnotic.
flurazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a 2-(diethylamino)ethyl group, 2-fluorophenyl group and chloro group at positions 1, 5 and 7, respectively. It is a partial agonist of GABAA receptors and used for the treatment of insomnia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Enciprazine was selected for clinical investigations." | 1.28 | Chemistry and pharmacology of the non-benzodiazepine anxiolytic enciprazine and related compounds. ( Engel, J; Fleischhauer, I; Jakovlev, V; Johanson, CE; Kleemann, A; Kutscher, B; Nickel, B; Rauer, H; Szelenyi, I; Werner, U, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (86.96) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Engel, J | 1 |
| Fleischhauer, I | 1 |
| Jakovlev, V | 1 |
| Kleemann, A | 1 |
| Kutscher, B | 1 |
| Nickel, B | 1 |
| Rauer, H | 1 |
| Werner, U | 1 |
| Szelenyi, I | 1 |
| Johanson, CE | 1 |
| Zhang, LP | 1 |
| Wang, L | 1 |
| Cohen, ES | 1 |
| Holman, RC | 1 |
| James, RT | 1 |
| Dean, BC | 1 |
| Rogalski, CJ | 1 |
| Lahmeyer, HW | 1 |
| Reynolds, IS | 1 |
| Hubbard, B | 1 |
| Kripke, DF | 1 |
| Solomon, D | 1 |
| Medd, BH | 1 |
| Greenblatt, DJ | 3 |
| Shader, RI | 1 |
| Koch-Weser, J | 2 |
| Miller, RR | 2 |
| Banerjee, U | 2 |
| Kluger, NJ | 1 |
| Clifford, JS | 1 |
| Cavanagh, RJ | 1 |
| Griffith, WL | 1 |
| Rosenberg, HC | 2 |
| Chiu, TH | 2 |
| Soldatos, CR | 1 |
| Kales, A | 2 |
| Bixler, EO | 2 |
| Vela-Bueno, A | 1 |
| Tan, TL | 1 |
| Scharf, MB | 1 |
| Kales, JD | 1 |
| Hussey, HH | 1 |
4 reviews available for flurazepam and Chemical Dependence
| Article | Year |
|---|---|
Flurazepam hydrochloride.
Topics: Aggression; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Blood Circulation; Brai | 1975 |
Time course for development of benzodiazepine tolerance and physical dependence.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Diazepam; Drug Tolerance; Flumazenil; Flurazepam; H | 1985 |
Behavioral side effects of benzodiazepine hypnotics.
Topics: Amnesia; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Flurazepam; Humans; Hypnotics and Sedatives; | 1985 |
Drug therapy reviews. Rational use of psychotropic drugs. I. Hypnotics.
Topics: Barbiturates; Chlorates; Dose-Response Relationship, Drug; Dreams; Drug Interactions; Drug Synergism | 1974 |
1 trial available for flurazepam and Chemical Dependence
| Article | Year |
|---|---|
Flurazepam (Dalmane).
Topics: Anti-Anxiety Agents; Clinical Trials as Topic; Flurazepam; Half-Life; Humans; Sleep Initiation and M | 1975 |
18 other studies available for flurazepam and Chemical Dependence
| Article | Year |
|---|---|
Chemistry and pharmacology of the non-benzodiazepine anxiolytic enciprazine and related compounds.
Topics: Aggression; Animals; Anti-Anxiety Agents; Behavior, Animal; Chemical Phenomena; Chemistry; Explorato | 1990 |
Changes of brain neuropeptide Y and its receptors in rats with flurazepam tolerance and dependence.
Topics: Animals; Dentate Gyrus; Drug Tolerance; Flurazepam; Hippocampus; Male; Neuropeptide Y; Rats; Rats, S | 2005 |
An integrated approach to iatrogenic drug abuse in a closed delivery system.
Topics: Adult; Aged; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Doxepin; Drug and Narcotic Control; Dr | 1980 |
Reducing the risk: barbiturate substitution with a benzodiazepine.
Topics: Adult; Aged; Barbiturates; Female; Flurazepam; Humans; Male; Middle Aged; Risk; Sleep Wake Disorders | 1983 |
Effect of the hypnotic flurazepam on the sleep of pentazocine and heroin addicts during withdrawal.
Topics: Adolescent; Adult; Flurazepam; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Pentazocine; | 1983 |
Systematic review of the benzodiazepines. Guidelines for data sheets on diazepam, chlordiazepoxide, medazepam, clorazepate, lorazepam, oxazepam, temazepam, triazolam, nitrazepam, and flurazepam. Committee on the Review of Medicines.
Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Flurazepam; Humans; Lorazepam; | 1980 |
Digital loss resulting from drug abuse.
Topics: Adult; Fingers; Flurazepam; Gangrene; Humans; Male; Methadone; Substance-Related Disorders | 1980 |
Hypnotic and minor tranquilizer use among inpatients and after discharge.
Topics: Aftercare; Anti-Anxiety Agents; Chloral Hydrate; Flurazepam; Follow-Up Studies; Hospitalization; Hum | 1976 |
High-dose benzodiazepines in the treatment of severe neurotic anxiety.
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Female; Flurazepam; Humans; Male; Oxa | 1978 |
Sleeping pills and insomnia.
Topics: Anti-Anxiety Agents; Flurazepam; Humans; Sleep Initiation and Maintenance Disorders; Substance-Relat | 1979 |
A guide to the use of hypnotic drugs.
Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Drug Interactions; Flurazepam; | 1979 |
Conditioned learning in young rats born of drug-addicted parents and raised on addictive drugs.
Topics: Animals; Animals, Newborn; Avoidance Learning; Birth Weight; Body Weight; Conditioning, Psychologica | 1975 |
A case of a chemically dependent patient with a thalamic pain syndrome treated with amitriptyline.
Topics: Alcoholism; Amitriptyline; Cerebral Infarction; Flurazepam; Follow-Up Studies; Humans; Male; Middle | 1991 |
Blood pressure response to Ro15-1788, a benzodiazepine antagonist.
Topics: Animals; Benzodiazepinones; Blood Pressure; Cats; Convulsants; Diazepam; Drug Tolerance; Flumazenil; | 1985 |
Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence.
Topics: Adult; Age Factors; Aged; Amobarbital; Chloral Hydrate; Chronic Disease; Dreams; Drug Therapy, Combi | 1974 |
Editorial: Insomnia.
Topics: Apnea; Chronic Disease; Flurazepam; Humans; Hypnotics and Sedatives; Iatrogenic Disease; Male; Middl | 1974 |
The archaic barbiturate hypnotics.
Topics: Barbiturates; Biotransformation; Costs and Cost Analysis; Drug Antagonism; Drug Prescriptions; Flura | 1974 |
Programmed self-administration of potentially addictive drugs in young rats and its effects on learning.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Drug Tolerance; Ethanol; Extinction, Psy | 1974 |