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flurazepam and Anxiety

flurazepam has been researched along with Anxiety in 17 studies

Flurazepam: A benzodiazepine derivative used mainly as a hypnotic.
flurazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a 2-(diethylamino)ethyl group, 2-fluorophenyl group and chloro group at positions 1, 5 and 7, respectively. It is a partial agonist of GABAA receptors and used for the treatment of insomnia.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Some withdrawal symptoms were distinct from those of anxiety (e."2.66Withdrawal reaction after long-term therapeutic use of benzodiazepines. ( Busto, U; Cappell, H; Naranjo, CA; Sanchez-Craig, M; Sellers, EM; Sykora, K, 1986)
"Zopiclone was slightly superior to nitrazepam but was inferior both to flurazepam and flunitrazepam."2.65Comparative study of zopiclone, a novel hypnotic, and three benzodiazepines. ( Giercksky, KE; Wickstrøm, E, 1980)
"Lormetazepam (1 and 2 mg) was tested against flurazepam (30 mg) and placebo in 60 patients (15 per treatment group) with initial, intermediate, or late insomnia."2.65Comparative study of lormetazepam and flurazepam in the treatment of insomnia. ( Melo de Paula, AJ, 1984)
"Flurazepam is a long elimination half-life drug, and there is significant daytime sedation during short term use; with continued use this effect diminishes."2.36Sleep laboratory studies of hypnotic drugs: efficacy and withdrawal effects. ( Kales, A; Kales, JD, 1983)
"The diagnosis and treatment of insomnia is a major clinical issue."2.36Rational basis for the use of sleeping pills. ( Dement, WC, 1983)
" Chronic administration dissociated the pattern of results produced by sodium phenobarbitone (35 mg/kg) from that produced by flurazepam (0."1.26A test of anxiety that distinguishes between the actions of benzodiazepines and those of other minor tranquilisers and of stimulants. ( File, SE; Hyde, JR, 1979)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199016 (94.12)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xiang, K1
Tietz, EI1
Wickstrøm, E1
Giercksky, KE1
Kales, A2
Kales, JD1
Conell, LJ1
Berlin, RM1
Dement, WC1
Melo de Paula, AJ1
Kazarian, SS1
Tekatch, GM1
Ifabumuyi, OI1
Deinum, EJ1
Merskey, H1
File, SE1
Hyde, JR1
Becker, CE1
Roe, R1
Scott, R1
Tong, T1
Boerner, U1
Luce, J1
Sambrooks, JE1
MacCulloch, MJ1
Brose, N1
O'Neill, RD1
Boutelle, MG1
Fillenz, M1
Busto, U1
Sellers, EM1
Naranjo, CA1
Cappell, H1
Sanchez-Craig, M1
Sykora, K1
Luyk, NH1
Weaver, JM1
Beck, FM1
Loetscher, CA1
Sacks, J1
Soldatos, CR1
Bixler, EO1
Vela-Bueno, A1
Itil, TM1
Polvan, N1
Egilmez, S1
Saletu, B1
Marasa, J1
Ghisoni, T1
Poggi, E1

Reviews

3 reviews available for flurazepam and Anxiety

ArticleYear
Sleep laboratory studies of hypnotic drugs: efficacy and withdrawal effects.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:2

    Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Dose-Response Relationship, Drug; Fl

1983
Rational basis for the use of sleeping pills.
    Pharmacology, 1983, Volume: 27 Suppl 2

    Topics: Anxiety; Chronic Disease; Flurazepam; Humans; Hypnotics and Sedatives; Kinetics; Sleep; Sleep Initia

1983
Behavioral side effects of benzodiazepine hypnotics.
    Clinical neuropharmacology, 1985, Volume: 8 Suppl 1

    Topics: Amnesia; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Flurazepam; Humans; Hypnotics and Sedatives;

1985

Trials

5 trials available for flurazepam and Anxiety

ArticleYear
Comparative study of zopiclone, a novel hypnotic, and three benzodiazepines.
    European journal of clinical pharmacology, 1980, Volume: 17, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Anxiety; Attention; Azabicyclo Compounds; Female; Flunitrazepam; Fluraze

1980
Comparative study of lormetazepam and flurazepam in the treatment of insomnia.
    Clinical therapeutics, 1984, Volume: 6, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relati

1984
The thymoleptic action of two salts of flurazepam ('Dalmane').
    Current medical research and opinion, 1975, Volume: 3, Issue:4

    Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Emotions; Flurazepam; Health; H

1975
Withdrawal reaction after long-term therapeutic use of benzodiazepines.
    The New England journal of medicine, 1986, Oct-02, Volume: 315, Issue:14

    Topics: Adolescent; Adult; Aged; Anxiety; Benzodiazepines; Diazepam; Double-Blind Method; Female; Flurazepam

1986
The effectiveness of flurazepam as night sedation prior to the removal of third molars.
    International journal of oral and maxillofacial surgery, 1988, Volume: 17, Issue:6

    Topics: Adult; Anxiety; Double-Blind Method; Female; Flurazepam; Humans; Male; Molar, Third; Premedication;

1988

Other Studies

9 other studies available for flurazepam and Anxiety

ArticleYear
Benzodiazepine-induced hippocampal CA1 neuron alpha-amino-3-hydroxy-5-methylisoxasole-4-propionic acid (AMPA) receptor plasticity linked to severity of withdrawal anxiety: differential role of voltage-gated calcium channels and N-methyl-D-aspartic acid re
    Behavioural pharmacology, 2007, Volume: 18, Issue:5-6

    Topics: Animals; Anxiety; Benzodiazepines; Calcium Channels, L-Type; Disease Models, Animal; Dizocilpine Mal

2007
Choice of benzodiazepines.
    The Medical letter on drugs and therapeutics, 1981, May-01, Volume: 23, Issue:9

    Topics: Aged; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Diazepam; Flurazepam; Half-Life; Humans; Liver

1981
Withdrawal after substitution of a short-acting for a long-acting benzodiazepine.
    JAMA, 1983, Nov-25, Volume: 250, Issue:20

    Topics: Anti-Anxiety Agents; Anxiety; Chronic Disease; Delayed-Action Preparations; Diazepam; Flurazepam; Ha

1983
Effects of antianxiety agents on relaxation training: a preliminary investigation.
    Canadian Psychiatric Association journal, 1978, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Diazepam; Female; Flurazepam; Humans; Male; M

1978
A test of anxiety that distinguishes between the actions of benzodiazepines and those of other minor tranquilisers and of stimulants.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:1

    Topics: Amphetamine; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Central Nervous System Stimulants; Flu

1979
Rational drug therapy of alcoholism with sedative hypnotic drugs! Is this possible?
    Annals of the New York Academy of Sciences, 1975, Apr-25, Volume: 252

    Topics: Administration, Oral; Alcoholism; Antipsychotic Agents; Anxiety; Barbiturates; Community Mental Heal

1975
The effects of anxiolytic and anxiogenic benzodiazepine receptor ligands on motor activity and levels of ascorbic acid in the nucleus accumbens and striatum of the rat.
    Neuropharmacology, 1989, Volume: 28, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Appetite Depressants; Ascorbic Acid; Carbolines; Circadian Rh

1989
Anxiolytic effects of a new triazolobenzodiazepine, U-31,889.
    Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:9

    Topics: Adult; Animals; Anxiety; Behavior, Animal; Benzodiazepinones; Blood Circulation; Central Nervous Sys

1973
[Flurazepam in depressive anxiety syndromes].
    Sistema nervoso, 1971, Volume: 23, Issue:7

    Topics: Adjustment Disorders; Adult; Aged; Anxiety; Anxiety Disorders; Benzodiazepinones; Depression; Diazep

1971