fluprostenol and Pleurisy

fluprostenol has been researched along with Pleurisy* in 1 studies

Other Studies

1 other study(ies) available for fluprostenol and Pleurisy

Article	Year
Prostaglandin F2alpha produced by inducible cyclooxygenase may contribute to the resolution of inflammation. Inflammopharmacology, 2005, Volume: 12, Issue:5-6 Cyclooxygenase-2 may play a role in resolution of carrageenan-induced pleurisy in rats by generating anti-inflammatory prostanoids. Here, we show exudate prostaglandin F2alpha concentrations rise during resolution of this model. These were reduced by the selective cyclooxygenase-2 inhibitor NS-398, which exacerbated inflammation. Concomitant treatment with NS-398 and the synthetic FP receptor agonist fluprostenol reversed this exacerbation. This suggests prostaglandin F2alpha produced by cyclooxygenase-2 contributes to resolution of this inflammatory reaction. Topics: Analysis of Variance; Animals; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprost; Inflammation; Nitrobenzenes; Pleurisy; Prostaglandins F, Synthetic; Rats; Rats, Wistar; Receptors, Prostaglandin; Sulfonamides	2005

Article

Year

Prostaglandin F2alpha produced by inducible cyclooxygenase may contribute to the resolution of inflammation.

Inflammopharmacology, 2005, Volume: 12, Issue:5-6

Cyclooxygenase-2 may play a role in resolution of carrageenan-induced pleurisy in rats by generating anti-inflammatory prostanoids. Here, we show exudate prostaglandin F2alpha concentrations rise during resolution of this model. These were reduced by the selective cyclooxygenase-2 inhibitor NS-398, which exacerbated inflammation. Concomitant treatment with NS-398 and the synthetic FP receptor agonist fluprostenol reversed this exacerbation. This suggests prostaglandin F2alpha produced by cyclooxygenase-2 contributes to resolution of this inflammatory reaction.

Topics: Analysis of Variance; Animals; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprost; Inflammation; Nitrobenzenes; Pleurisy; Prostaglandins F, Synthetic; Rats; Rats, Wistar; Receptors, Prostaglandin; Sulfonamides

2005