Page last updated: 2024-11-07

fluprednisolone and Corneal Edema

fluprednisolone has been researched along with Corneal Edema in 2 studies

Fluprednisolone: A synthetic glucocorticoid with anti-inflammatory properties.

Corneal Edema: An excessive amount of fluid in the cornea due to damage of the epithelium or endothelium causing decreased visual acuity.

Research Excerpts

ExcerptRelevanceReference
"In this high-dose pulsed-therapy regimen, difluprednate reduced inflammation more effectively than prednisolone acetate, resulting in more rapid return of vision."5.15A multicenter randomized controlled fellow eye trial of pulse-dosed difluprednate 0.05% versus prednisolone acetate 1% in cataract surgery. ( Donnenfeld, ED; Fiore, J; Gobbo, A; Holland, EJ; Perry, HD; Prince, J; Sandoval, HP; Shull, ER; Solomon, KD, 2011)
"Patients treated with difluprednate or loteprednol had statistically similar resolution of their AC cell grade and corneal edema at 1 day, 1 week, and 1 month postoperatively (P>0."3.88Comparison of Efficacy of Difluprednate 0.05% and Loteprednol Gel 0.5% After Cataract Surgery. ( Abessi, B; Brooksby, L; Schultze, RL, 2018)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abessi, B1
Brooksby, L1
Schultze, RL1
Donnenfeld, ED1
Holland, EJ1
Solomon, KD1
Fiore, J1
Gobbo, A1
Prince, J1
Sandoval, HP1
Shull, ER1
Perry, HD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Masked Multi-center Safety & Efficacy Study of the Effects of Preoperative & Postoperative Cataract Surgery Use of Difluprednate Ophthalmic Emulsion, 0.05% Compared to Prednisolone Acetate Ophthalmic Suspension 1% on Visual Acuity & Corneal [NCT01244334]Phase 452 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for fluprednisolone and Corneal Edema

ArticleYear
A multicenter randomized controlled fellow eye trial of pulse-dosed difluprednate 0.05% versus prednisolone acetate 1% in cataract surgery.
    American journal of ophthalmology, 2011, Volume: 152, Issue:4

    Topics: Aged; Aged, 80 and over; Cell Count; Cornea; Corneal Edema; Double-Blind Method; Endothelium, Cornea

2011

Other Studies

1 other study available for fluprednisolone and Corneal Edema

ArticleYear
Comparison of Efficacy of Difluprednate 0.05% and Loteprednol Gel 0.5% After Cataract Surgery.
    Eye & contact lens, 2018, Volume: 44 Suppl 2

    Topics: Aged; Aged, 80 and over; Anterior Chamber; Anti-Inflammatory Agents; Cataract Extraction; Cornea; Co

2018