flupirtine has been researched along with Disease Models, Animal in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Busquet, N; Diaz, MJ; Gonzalez, MI; Lam, PM; Laoprasert, M; Raol, YH; Sampath, D; White, AM | 1 |
| Huo, B; Jin, L; Li, H; Liu, R; Liu, S; Tang, L; Wang, Y; Yang, T; Zhang, F; Zhao, X | 1 |
| Raol, YH; Sampath, D; Valdez, R; White, AM | 1 |
| Fu, T; Guo, L; Huang, P; Li, C; Lu, Q; Xu, X; Yi, Z; Zhao, D | 1 |
| Doh-Ura, K; Teruya, K | 1 |
| Cooke, I; Goodchild, CS; Kolosov, A; Tucker, AP | 1 |
| Brooks-Kayal, AR; Cooper, EC; Keating, JG; Lapides, DA; Raol, YH | 1 |
| Gurney, AM; MacLean, MR; Morecroft, I; Murray, A; Nilsen, M | 1 |
| Dalle, C; Gamper, N; Ooi, L; Robertson, B; Rose, K; Wood, IC | 1 |
| He, X; Liu, W; Liu, Y; Peng, B; Wang, H; Wang, Y; Yin, J; Yu, F | 1 |
| Cooke, I; Goodchild, CS; Kolosov, A; Williams, ED | 1 |
| Diamantis, W; Gordon, R; Sofia, RD | 1 |
1 review(s) available for flupirtine and Disease Models, Animal
| Article | Year |
|---|---|
Insights from Therapeutic Studies for PrP Prion Disease.
Topics: Aminopyridines; Animals; Creutzfeldt-Jakob Syndrome; Disease Models, Animal; Doxycycline; Drug Discovery; History, 20th Century; History, 21st Century; Humans; Pentosan Sulfuric Polyester; Quinacrine; Randomized Controlled Trials as Topic; Translational Research, Biomedical | 2017 |
13 other study(ies) available for flupirtine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Effects of a potassium channel opener on brain injury and neurologic outcomes in an animal model of neonatal hypoxic-ischemic injury.
Topics: Aminopyridines; Animals; Animals, Newborn; Anticonvulsants; Brain; Brain Injuries; Carotid Arteries; Cognition; Disease Models, Animal; Hand Strength; Hypoxia; Hypoxia-Ischemia, Brain; Male; Maze Learning; Motor Skills; Nervous System Diseases; Neuroprotection; Neuroprotective Agents; Potassium Channels; Quality of Life; Rats; Seizures | 2020 |
Antinociceptive Efficacy of Retigabine and Flupirtine for Gout Arthritis Pain.
Topics: Aminopyridines; Analgesics; Animals; Arthritis, Experimental; Arthritis, Gouty; Behavior, Animal; Carbamates; Disease Models, Animal; Hyperalgesia; KCNQ Potassium Channels; Male; Pain; Phenylenediamines; Rats; Rats, Sprague-Dawley; Uric Acid | 2020 |
Anticonvulsant effect of flupirtine in an animal model of neonatal hypoxic-ischemic encephalopathy.
Topics: Aminopyridines; Animals; Animals, Newborn; Anticonvulsants; Brain; Disease Models, Animal; Disease Progression; Electrocorticography; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Male; Phenobarbital; Random Allocation; Rats, Sprague-Dawley; Seizures; Time Factors | 2017 |
Flupirtine attenuates chronic restraint stress-induced cognitive deficits and hippocampal apoptosis in male mice.
Topics: Aminopyridines; Animals; Apoptosis; Chronic Disease; Cognition Disorders; Dendritic Spines; Disease Models, Animal; Hippocampus; Male; Maze Learning; Mice; Neurons; Neuroprotective Agents; Nootropic Agents; Random Allocation; Restraint, Physical; Spatial Memory; Stress, Psychological | 2015 |
Combination therapy with flupirtine and opioid: studies in rat pain models.
Topics: Aminopyridines; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Male; Morphine; Neuralgia; Pain Measurement; Rats; Rats, Wistar; Treatment Outcome | 2008 |
A KCNQ channel opener for experimental neonatal seizures and status epilepticus.
Topics: Aminopyridines; Animals; Animals, Newborn; Anticonvulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Female; Flurothyl; Kainic Acid; KCNQ Potassium Channels; Male; Phenobarbital; Pregnancy; Rats; Seizures; Spectrum Analysis; Status Epilepticus; Time Factors | 2009 |
Treatment with the Kv7 potassium channel activator flupirtine is beneficial in two independent mouse models of pulmonary hypertension.
Topics: Aminopyridines; Animals; Disease Models, Animal; Female; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Mice; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Channels, Voltage-Gated; Pulmonary Artery; Serotonin Plasma Membrane Transport Proteins | 2009 |
Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury.
Topics: Aminopyridines; Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Chronic Disease; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glycoproteins; Hyperalgesia; Indoles; KCNQ2 Potassium Channel; Lectins; Lidocaine; Male; Membrane Potentials; Neurofilament Proteins; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Repressor Proteins; RNA, Messenger; Sciatic Neuropathy; TRPV Cation Channels; Versicans | 2011 |
Protective effect of the KCNQ activator flupirtine on a model of repetitive febrile seizures.
Topics: Aminopyridines; Analgesics; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Female; Fever; KCNQ Potassium Channels; Male; Maze Learning; Memory; Nerve Degeneration; Neuroprotective Agents; Phenobarbital; Rats; Rats, Sprague-Dawley; Risk Factors; Secondary Prevention; Seizures, Febrile | 2011 |
Flupirtine enhances the anti-hyperalgesic effects of morphine in a rat model of prostate bone metastasis.
Topics: Aminopyridines; Analgesics; Animals; Bone Neoplasms; Disease Models, Animal; Hyperalgesia; Male; Morphine; Pain; Prostatic Neoplasms; Rats; Rats, Wistar | 2012 |
Abuse potential and physical dependence liability studies with flupirtine maleate in laboratory animals.
Topics: Aminopyridines; Analgesics; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Macaca mulatta; Mice; Mice, Inbred Strains; Rats; Substance-Related Disorders | 1987 |