flupirtine has been researched along with Chemical Dependence in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Connemann, BJ; Freudenmann, RW; Gahr, M; Hiemke, C; Schönfeldt-Lecuona, C | 1 |
| Clepce, M; Kornhuber, J; Reich, K; Thuerauf, N; Wielopolski, J | 1 |
| Liu, Y; Maier, A; Scholze, A; Tepel, M; Westhoff, TH | 1 |
| Borbe, HO; Nickel, B; Szelenyi, I | 1 |
| Bigelow, GE; Funderburk, FR; Liebson, IA; Preston, KL | 1 |
| Aigner, M; Herrmann, WM; Kern, U | 1 |
| Aledter, A; Nickel, B | 1 |
| Herz, A; Jakovlev, V; Nickel, B; Tibes, U | 1 |
| Diamantis, W; Gordon, R; Sofia, RD | 1 |
2 trial(s) available for flupirtine and Chemical Dependence
| Article | Year |
|---|---|
Evaluation of the abuse potential of the novel analgesic flupirtine maleate.
Topics: Adult; Affect; Aminopyridines; Analgesics; Arousal; Attention; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Lorazepam; Male; Neuropsychological Tests; Psychomotor Performance; Substance-Related Disorders | 1991 |
On the adverse reactions and efficacy of long-term treatment with flupirtine: preliminary results of an ongoing twelve-month study with 200 patients suffering from chronic pain states in arthrosis or arthritis.
Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Analgesics; Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Long-Term Care; Male; Middle Aged; Palliative Care; Substance Withdrawal Syndrome; Substance-Related Disorders | 1987 |
7 other study(ies) available for flupirtine and Chemical Dependence
| Article | Year |
|---|---|
Abuse liability of flupirtine revisited: implications of spontaneous reports of adverse drug reactions.
Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Analgesics; Female; Germany; Humans; Male; Middle Aged; Substance-Related Disorders; Young Adult | 2013 |
Long-term use of flupirtine leads to withdrawal symptoms and is associated with dependency.
Topics: Adult; Aminopyridines; Analgesics; Butyrophenones; Female; Humans; Substance Withdrawal Syndrome; Substance-Related Disorders | 2013 |
Green urine following exposure to flupirtine.
Topics: Adult; Aminopyridines; Analgesics; Color; Diagnosis, Differential; Humans; Male; Substance-Related Disorders; Urinalysis | 2010 |
Investigations with the novel non-opioid analgesic flupirtine in regard to possible benzodiazepine-like abuse inducing potential.
Topics: Aminopyridines; Analgesics; Animals; Anti-Anxiety Agents; Binding, Competitive; Body Weight; Brain Chemistry; Conditioning, Operant; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Lorazepam; Male; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, GABA-A; Reinforcement Schedule; Substance-Related Disorders | 1990 |
Comparative physical dependence studies in rats with flupirtine and opiate receptor stimulating analgesics.
Topics: Aminopyridines; Analgesics; Animals; Body Weight; Buprenorphine; Codeine; Female; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance-Related Disorders; Tramadol | 1987 |
[Mechanism of action of the analgesic flupirtine].
Topics: Aminopyridines; Analgesics; Animals; Brain; Cyproheptadine; Fenclonine; Injections, Intraventricular; Injections, Spinal; Mice; Naloxone; Rats; Receptors, Opioid; Substance-Related Disorders | 1985 |
Abuse potential and physical dependence liability studies with flupirtine maleate in laboratory animals.
Topics: Aminopyridines; Analgesics; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Macaca mulatta; Mice; Mice, Inbred Strains; Rats; Substance-Related Disorders | 1987 |