Page last updated: 2024-08-23

flupirtine and Chemical Dependence

flupirtine has been researched along with Chemical Dependence in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Connemann, BJ; Freudenmann, RW; Gahr, M; Hiemke, C; Schönfeldt-Lecuona, C1
Clepce, M; Kornhuber, J; Reich, K; Thuerauf, N; Wielopolski, J1
Liu, Y; Maier, A; Scholze, A; Tepel, M; Westhoff, TH1
Borbe, HO; Nickel, B; Szelenyi, I1
Bigelow, GE; Funderburk, FR; Liebson, IA; Preston, KL1
Aigner, M; Herrmann, WM; Kern, U1
Aledter, A; Nickel, B1
Herz, A; Jakovlev, V; Nickel, B; Tibes, U1
Diamantis, W; Gordon, R; Sofia, RD1

Trials

2 trial(s) available for flupirtine and Chemical Dependence

ArticleYear
Evaluation of the abuse potential of the novel analgesic flupirtine maleate.
    Drug and alcohol dependence, 1991, Volume: 27, Issue:2

    Topics: Adult; Affect; Aminopyridines; Analgesics; Arousal; Attention; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Lorazepam; Male; Neuropsychological Tests; Psychomotor Performance; Substance-Related Disorders

1991
On the adverse reactions and efficacy of long-term treatment with flupirtine: preliminary results of an ongoing twelve-month study with 200 patients suffering from chronic pain states in arthrosis or arthritis.
    Postgraduate medical journal, 1987, Volume: 63 Suppl 3

    Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Analgesics; Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Long-Term Care; Male; Middle Aged; Palliative Care; Substance Withdrawal Syndrome; Substance-Related Disorders

1987

Other Studies

7 other study(ies) available for flupirtine and Chemical Dependence

ArticleYear
Abuse liability of flupirtine revisited: implications of spontaneous reports of adverse drug reactions.
    Journal of clinical pharmacology, 2013, Volume: 53, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Analgesics; Female; Germany; Humans; Male; Middle Aged; Substance-Related Disorders; Young Adult

2013
Long-term use of flupirtine leads to withdrawal symptoms and is associated with dependency.
    Pharmacopsychiatry, 2013, Volume: 46, Issue:7

    Topics: Adult; Aminopyridines; Analgesics; Butyrophenones; Female; Humans; Substance Withdrawal Syndrome; Substance-Related Disorders

2013
Green urine following exposure to flupirtine.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2010, Volume: 56, Issue:5

    Topics: Adult; Aminopyridines; Analgesics; Color; Diagnosis, Differential; Humans; Male; Substance-Related Disorders; Urinalysis

2010
Investigations with the novel non-opioid analgesic flupirtine in regard to possible benzodiazepine-like abuse inducing potential.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:8

    Topics: Aminopyridines; Analgesics; Animals; Anti-Anxiety Agents; Binding, Competitive; Body Weight; Brain Chemistry; Conditioning, Operant; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Lorazepam; Male; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, GABA-A; Reinforcement Schedule; Substance-Related Disorders

1990
Comparative physical dependence studies in rats with flupirtine and opiate receptor stimulating analgesics.
    Postgraduate medical journal, 1987, Volume: 63 Suppl 3

    Topics: Aminopyridines; Analgesics; Animals; Body Weight; Buprenorphine; Codeine; Female; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance-Related Disorders; Tramadol

1987
[Mechanism of action of the analgesic flupirtine].
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:9

    Topics: Aminopyridines; Analgesics; Animals; Brain; Cyproheptadine; Fenclonine; Injections, Intraventricular; Injections, Spinal; Mice; Naloxone; Rats; Receptors, Opioid; Substance-Related Disorders

1985
Abuse potential and physical dependence liability studies with flupirtine maleate in laboratory animals.
    Postgraduate medical journal, 1987, Volume: 63 Suppl 3

    Topics: Aminopyridines; Analgesics; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Macaca mulatta; Mice; Mice, Inbred Strains; Rats; Substance-Related Disorders

1987