Page last updated: 2024-08-23

flupirtine and Ache

flupirtine has been researched along with Ache in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (26.92)	18.7374
1990's	3 (11.54)	18.2507
2000's	6 (23.08)	29.6817
2010's	9 (34.62)	24.3611
2020's	1 (3.85)	2.80

Authors

Authors	Studies
Huo, B; Jin, L; Li, H; Liu, R; Liu, S; Tang, L; Wang, Y; Yang, T; Zhang, F; Zhao, X	1
Nair, AS	1
Puljak, L	1
Lawson, K	1
Fan, X; Li, H; Liu, Y; Shao, D; Zhang, D; Zhang, F	1
Lopez-Garcia, JA; Rivera-Arconada, I; Vicente-Baz, J	1
Devulder, J	1
Alekseev, VV	1
Gamper, N; Huang, D; Linley, JE; Pettinger, L	1
Cooke, I; Goodchild, CS; Kolosov, A; Williams, ED	1
Miethe, D; Pittrow, D; Ringe, JD; Wegscheider, K	1
Mueller-Schwefe, G	1
Müller-Schwefe, G	1
Dworetzky, SI; Wua, YJ	1
Althaus, M; Hanschmann, A; Klein, T; Magerl, W; Treede, RD	1
Finlay, BR; Million, R; Whittington, JR	1
Fitton, A; Friedel, HA	1
Lobisch, M; Lüben, V; Müller, H; Wörz, R	1
Aigner, M; Herrmann, WM; Hiersemenzel, R; Lobisch, M; Michel, I; Riethmüller-Winzen, H	1
Hezky, P; Krejcí, I; Proska, J; Rádl, S	1
Bromm, B; Ganzel, R; Herrmann, WM; Meier, W; Scharein, E	2
Scheef, W	1
Hummel, T; Kobal, G	1
Engel, J; Nickel, B; Szelenyi, I	1
Scheef, W; Wolf-Gruber, D	1

Reviews

4 review(s) available for flupirtine and Ache

Article	Year
Flupirtine in pain management: pharmacological properties and clinical use. CNS drugs, 2010, Volume: 24, Issue:10 Topics: Aminopyridines; Analgesics; Humans; Pain	2010
[Flupirtin (katadolon): a nonstandard action on pain transmission]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2011, Volume: 111, Issue:4 Topics: Aminopyridines; Analgesics, Non-Narcotic; Humans; Pain	2011
Recent developments on KCNQ potassium channel openers. Current medicinal chemistry, 2005, Volume: 12, Issue:4 Topics: Acrylamides; Aminopyridines; Benzamides; Carbamates; Epilepsy; Humans; Indoles; Ion Channel Gating; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Migraine Disorders; Oxindoles; Pain; Phenylenediamines; Potassium Channels, Voltage-Gated	2005
Flupirtine. A review of its pharmacological properties, and therapeutic efficacy in pain states. Drugs, 1993, Volume: 45, Issue:4 Topics: Aminopyridines; Analgesics; Animals; Humans; Pain	1993

Trials

9 trial(s) available for flupirtine and Ache

Article	Year
Analgesic efficacy of flupirtine in primary care of patients with osteoporosis related pain. A multivariate analysis. Arzneimittel-Forschung, 2003, Volume: 53, Issue:7 Topics: Aged; Aminopyridines; Analgesics; Female; Humans; Male; Middle Aged; Multivariate Analysis; Osteoporosis; Pain; Pain Measurement; Prospective Studies	2003
[Parental administration of flupirtine in musculoskeletal pain. Results of a postmarket surveillance study]. MMW Fortschritte der Medizin, 2004, May-24, Volume: 146 Spec No 2 Topics: Acute Disease; Aminopyridines; Analgesics; Humans; Injections, Intramuscular; Membrane Potentials; Neurons; Pain; Pain Measurement; Potassium Channels; Receptors, N-Methyl-D-Aspartate	2004
Antihyperalgesic and analgesic properties of the N-methyl-D-aspartate (NMDA) receptor antagonist neramexane in a human surrogate model of neurogenic hyperalgesia. European journal of pain (London, England), 2008, Volume: 12, Issue:1 Topics: Aminopyridines; Analgesics; Capsaicin; Cross-Over Studies; Cyclopentanes; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hyperalgesia; Injections, Intradermal; Nervous System Diseases; Pain; Physical Stimulation; Receptors, N-Methyl-D-Aspartate; Treatment Outcome	2008
Clinical trial of flupirtine maleate in patients with migraine. Current medical research and opinion, 1984, Volume: 9, Issue:3 Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Aminopyridines; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Pain; Random Allocation; Sex Factors	1984
[Treatment of tumor pain with flupirtine. Results of a double-blind study versus tramadol]. Fortschritte der Medizin, 1994, Jul-10, Volume: 112, Issue:19 Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Analgesics; Female; Humans; Male; Middle Aged; Neoplasms; Pain; Pain Measurement; Prospective Studies; Tramadol	1994
[Long-term tolerance of flupirtine. Open multicenter study over one year]. Fortschritte der Medizin, 1993, May-30, Volume: 111, Issue:15 Topics: Adult; Aged; Aminopyridines; Analgesics; Chronic Disease; Female; Humans; Long-Term Care; Male; Middle Aged; Musculoskeletal Diseases; Pain; Pain Measurement	1993
The analgesic efficacy of flupirtine in comparison to pentazocine and placebo assessed by EEG and subjective pain ratings. Postgraduate medical journal, 1987, Volume: 63 Suppl 3 Topics: Aminopyridines; Analgesics; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Humans; Male; Pain; Pain Measurement; Palliative Care; Pentazocine	1987
Analgesic efficacy and safety of oral flupirtine in the treatment of cancer pain. Postgraduate medical journal, 1987, Volume: 63 Suppl 3 Topics: Administration, Oral; Aminopyridines; Analgesics; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Neoplasms; Pain; Palliative Care; Pentazocine; Random Allocation	1987
[Flupirtine in patients with cancer pain]. Arzneimittel-Forschung, 1985, Volume: 35, Issue:1 Topics: Aged; Aminopyridines; Analgesics; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Neoplasms; Pain; Pentazocine; Random Allocation	1985

Other Studies

13 other study(ies) available for flupirtine and Ache

Article	Year
Antinociceptive Efficacy of Retigabine and Flupirtine for Gout Arthritis Pain. Pharmacology, 2020, Volume: 105, Issue:7-8 Topics: Aminopyridines; Analgesics; Animals; Arthritis, Experimental; Arthritis, Gouty; Behavior, Animal; Carbamates; Disease Models, Animal; Hyperalgesia; KCNQ Potassium Channels; Male; Pain; Phenylenediamines; Rats; Rats, Sprague-Dawley; Uric Acid	2020
Flupirtine: A Less-Explored, Neglected Nonopioid Analgesic. Anesthesia and analgesia, 2018, Volume: 126, Issue:4 Topics: Aminopyridines; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Pain	2018
Flupirtine, an Effective Analgesic, but Hepatotoxicity Should Limit Its Use. Anesthesia and analgesia, 2018, Volume: 127, Issue:1 Topics: Aminopyridines; Analgesics; Chemical and Drug Induced Liver Injury; Humans; Pain	2018
Flupirtine Is an Effective Analgesic: Is the Associated Rare Liver Injury a Limiting Factor to Its Use? Anesthesia and analgesia, 2018, Volume: 127, Issue:2 Topics: Aminopyridines; Analgesics; Humans; Liver; Pain	2018
Suppression of KCNQ/M Potassium Channel in Dorsal Root Ganglia Neurons Contributes to the Development of Osteoarthritic Pain. Pharmacology, 2019, Volume: 103, Issue:5-6 Topics: Aminopyridines; Analgesics; Animals; Anthracenes; Arthritis, Experimental; Behavior, Animal; Ganglia, Spinal; Hyperalgesia; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Osteoarthritis; Pain; Rats; Rats, Sprague-Dawley	2019
Targeting Kv7 channels in pain pathways. Oncotarget, 2017, Feb-21, Volume: 8, Issue:8 Topics: Aminopyridines; Animals; Carbamates; Deafness; Epilepsy; Humans; Inflammation; KCNQ Potassium Channels; Long QT Syndrome; Mutation; Neurons; Pain; Pain Management; Phenylenediamines; Protein Conformation	2017
M channel enhancers and physiological M channel block. The Journal of physiology, 2012, Feb-15, Volume: 590, Issue:4 Topics: Aminopyridines; Animals; Bradykinin; Calcium; Carbamates; CHO Cells; Cricetinae; Cricetulus; Ganglia, Spinal; Hydrogen Peroxide; Inflammation; KCNQ Potassium Channels; Organometallic Compounds; Pain; Phenylenediamines; Phosphatidylinositol 4,5-Diphosphate; Pyridines; Rats; Rats, Wistar; Sensory Receptor Cells; Type C Phospholipases	2012
Flupirtine enhances the anti-hyperalgesic effects of morphine in a rat model of prostate bone metastasis. Pain medicine (Malden, Mass.), 2012, Volume: 13, Issue:11 Topics: Aminopyridines; Analgesics; Animals; Bone Neoplasms; Disease Models, Animal; Hyperalgesia; Male; Morphine; Pain; Prostatic Neoplasms; Rats; Rats, Wistar	2012
[Flupirtine in acute and chronic pain associated with muscle tenseness. Results of a postmarket surveillance study]. MMW Fortschritte der Medizin, 2003, Mar-10, Volume: 145, Issue:12 Topics: Aminopyridines; Analgesics; Humans; Musculoskeletal Diseases; Neuroprotective Agents; Pain; Pain Measurement; Treatment Outcome	2003
Synthesis and analgesic activity of some quinazoline analogs of anpirtoline. Archiv der Pharmazie, 2000, Volume: 333, Issue:11 Topics: Aminopyridines; Analgesics; Animals; Hot Temperature; Male; Mice; Mice, Inbred Strains; Molecular Structure; Pain; Piperidines; Pyridines; Quinazolines; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Structure-Activity Relationship; Tramadol	2000
Effects of flupirtine on the pain-related evoked potential and the spontaneous EEG. Agents and actions, 1988, Volume: 23, Issue:1-2 Topics: Adult; Aminopyridines; Analgesics; Electroencephalography; Evoked Potentials; Female; Humans; Male; Pain	1988
Possible involvement of noradrenergic descending pain-modulating pathways in the mode of antinociceptive action of flupirtine, a novel non-opioid analgesic. Agents and actions, 1988, Volume: 23, Issue:1-2 Topics: Aminopyridines; Analgesics; Animals; Efferent Pathways; Male; Norepinephrine; Pain; Rats; Rats, Inbred Strains	1988
Pentazocine and flupirtine effects on spontaneous and evoked EEG activity. Neuropsychobiology, 1986, Volume: 16, Issue:2-3 Topics: Aminopyridines; Brain; Double-Blind Method; Electric Stimulation; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Humans; Male; Pain; Pentazocine	1986