Page last updated: 2024-10-27

fluphenazine depot and Schizophrenia

fluphenazine depot has been researched along with Schizophrenia in 199 studies

fluphenazine decanoate : The prodrug of fluphenazine, an antipsychotic drug used for the symptomatic management of psychosis in patients with schizophrenia.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of the use of moditen-depo and haloperidol decanoate as preventive anti-recurrence+ therapy was studied and compared in 2 groups of patients suffering from attack-like schizophrenia with frequent exacerbations."9.06[Clinical and economic approach to evaluation of the effectiveness of moditen-depot and haloperidol decanoate in the maintenance therapy of attack-like schizophrenia]. ( Kalugina, LI; Kopeĭko, GI; Kravchenko, NE; Mirzoian, MG; Ushakov, IuV, 1990)
"This paper reports a randomized, controlled, partially-blinded, flexible dose, parallel group, comparative study of the efficacy and tolerance of pipothiazine palmitate and fluphenazine decanoate in patients in remission from Schizophrenia over a 28 week period."9.06A comparative study of pipothiazine palmitate and fluphenazine decanoate in the maintenance of remission of schizophrenia. ( Gill, RC; Leong, OK; Tay, WK; Wong, KE, 1989)
"To assess the effects of fluphenazine decanoate and enanthate versus oral anti-psychotics and other depot neuroleptic preparations for individuals with schizophrenia in terms of clinical, social and economic outcomes."8.91Fluphenazine decanoate (depot) and enanthate for schizophrenia. ( Adams, CE; Asher, R; David, A; Eisenbruch, M; Jayaswal, A; Maayan, N; Quraishi, SN; Rathbone, J, 2015)
"To compare depot fluphenazine medication to oral fluphenazine for treatment of schizophrenia."8.80Depot fluphenazine for schizophrenia. ( Adams, CE; Eisenbruch, M, 2000)
" This study aimed to report a case with bradycardia induced by fluphenazine decanoate administration."8.12Fluphenazine decanoate-induced bradycardia: A case report. ( Azizi, M; Elyasi, F; Kamali, M; Zarghami, M, 2022)
" Results suggested an absorption half-life of 4 weeks, although, in three cases steady state was only achieved after 11 monthly injections."6.67Pharmacokinetics of haloperidol and fluphenazine decanoates in chronic schizophrenia. ( McCreadie, RG; Whitehead, A; Wiles, DH, 1990)
" The dosage equivalency of haloperidol decanoate (1."6.66A randomized clinical trial of haloperidol decanoate and fluphenazine decanoate in the outpatient treatment of schizophrenia. ( Annable, L; Campbell, W; Chouinard, G, 1989)
"Fluphenazine was significantly effective in treating symptoms such as emotional withdrawal, blunted affect, suspiciousness, thought disturbances, but not hallucinations."5.28Clinical and toxicological profile of fluphenazine decanoate in elderly chronic schizophrenia. ( Altamura, AC; Girardi, T; Mauri, MC; Panetta, B, 1990)
" Based on the study of plasma levels achieved with FPZ-D injection and oral FPZ-H (fluphenazine HC1) in 6 patients, the dosage requirement of FPZ-D appeared to be difficult to predict from the oral dosage of FPZ-H in the same patient."5.27Plasma levels of fluphenazine during fluphenazine decanoate treatment in schizophrenia. ( Casper, RC; Chang, SS; Davis, JM; Dysken, MW; Janicak, PG; Javaid, JI, 1985)
"Long-acting injectable risperidone was assessed in schizophrenia patients who were symptomatically stable on conventional depot antipsychotics and who were then switched to long-acting risperidone."5.11Long-acting injectable risperidone: safety and efficacy in stable patients switched from conventional depot antipsychotics. ( Eerdekens, E; Eerdekens, M; Jacko, M; Turner, M, 2004)
" With this in mind, we evaluated the usefulness of monitoring fluphenazine plasma levels for patients with schizophrenia who were receiving maintenance treatment with fluphenazine decanoate."5.10Fluphenazine plasma level monitoring for patients receiving fluphenazine decanoate. ( Aravagiri, M; Lebell, M; Marder, SR; Mintz, J; Wirshing, DA; Wirshing, WC, 2002)
"Fifty outpatients with schizophrenia or schizoaffective disorder were randomly assigned to receive 25 mg of fluphenazine decanoate intramuscularly either every 2 weeks or every 6 weeks for 54 weeks in a double-blind design."5.09Comparative effectiveness of fluphenazine decanoate injections every 2 weeks versus every 6 weeks. ( Breier, AF; Buchanan, RW; Carpenter, WT; Kirkpatrick, B; Lann, HD; Summerfelt, AT, 1999)
"Forty-one patients with DSM-III schizophrenia or schizoaffective disorder were assigned to either adjunctive lithium or placebo after at least 6 months of fluphenazine decanoate treatment to stabilize symptoms had failed."5.09Lithium augmentation fails to reduce symptoms in poorly responsive schizophrenic outpatients. ( Glick, ID; Jacobs, M; Ninan, PT; Odbert, CL; Robinson, D; Schulz, SC; Thompson, PA; Weiden, PJ; Yadalam, K, 1999)
"Fifty-three volunteer patients with recent-onset schizophrenia who had been clinically stabilized on a maintenance regimen of fluphenazine decanoate for a mean of 16."5.09Clinical outcome following neuroleptic discontinuation in patients with remitted recent-onset schizophrenia. ( Aravagiri, M; Bartzokis, G; Fogelson, DL; Gitlin, M; Mintz, J; Nuechterlein, K; Subotnik, KL; Ventura, J, 2001)
"This study examined substance use among a group of 37 schizophrenia patients participating in a year-long fluphenazine decanoate (FD; Prolixin) dosage reduction study (Inderbitzin et al."5.08Substance use: a powerful predictor of relapse in schizophrenia. ( Inderbitzin, LB; Kasckow, JW; Scheller-Gilkey, G; Swofford, CD, 1996)
"Eighty male outpatients with schizophrenia were stabilized with a low dose of fluphenazine decanoate (5 to 10 mg every 14 days), which was supplemented with oral fluphenazine (5 mg twice daily) or a placebo when they first met criteria for a prodromal period."5.08Two-year outcome of social skills training and group psychotherapy for outpatients with schizophrenia. ( Eckman, TA; Johnston, K; Lebell, M; Liberman, RP; Marder, SR; McKenzie, J; Mintz, J; Wirshing, WC; Zimmerman, K, 1996)
"This study evaluated the feasibility and impact of gradually reducing relatively high doses of fluphenazine decanoate by one-half for chronically impaired, poor inner-city patients with schizophrenia."5.07A double-blind dose-reduction trial of fluphenazine decanoate for chronic, unstable schizophrenic patients. ( Egan, GJ; Gloersen, BA; Inderbitzin, LB; Lewine, RR; Scheller-Gilkey, G; Swofford, CD; Vidanagama, BP; Waternaux, C, 1994)
"This paper reports a randomized, controlled, partially-blinded, flexible dose, parallel group, comparative study of the efficacy and tolerance of pipothiazine palmitate and fluphenazine decanoate in patients in remission from Schizophrenia over a 28 week period."5.06A comparative study of pipothiazine palmitate and fluphenazine decanoate in the maintenance of remission of schizophrenia. ( Gill, RC; Leong, OK; Tay, WK; Wong, KE, 1989)
" All patients had been diagnosed as having schizophrenia or schizoaffective disorder, all were receiving stable doses of fluphenazine decanoate, and all had received benztropine mesylate in an attempt to rule out neuroleptic-induced akinesia."5.06Adjunctive imipramine in the treatment of postpsychotic depression. A controlled trial. ( Cooper, TB; Fagerstrom, R; Morgan, V; Rifkin, A; Siris, SG, 1987)
"The efficacy of the use of moditen-depo and haloperidol decanoate as preventive anti-recurrence+ therapy was studied and compared in 2 groups of patients suffering from attack-like schizophrenia with frequent exacerbations."5.06[Clinical and economic approach to evaluation of the effectiveness of moditen-depot and haloperidol decanoate in the maintenance therapy of attack-like schizophrenia]. ( Kalugina, LI; Kopeĭko, GI; Kravchenko, NE; Mirzoian, MG; Ushakov, IuV, 1990)
"In an attempt to begin to establish minimum effective dosage requirements for the maintenance treatment of schizophrenia, we undertook a double-blind comparison of low-dose fluphenazine decanoate (1."5.05Low-dose neuroleptic treatment of outpatient schizophrenics. I. Preliminary results for relapse rates. ( Kane, JM; Ramos-Lorenzi, J; Reardon, G; Rifkin, A; Sarantakos, S; Schiebel, D; Woerner, M, 1983)
"To assess the effects of fluphenazine decanoate and enanthate versus oral anti-psychotics and other depot neuroleptic preparations for individuals with schizophrenia in terms of clinical, social and economic outcomes."4.91Fluphenazine decanoate (depot) and enanthate for schizophrenia. ( Adams, CE; Asher, R; David, A; Eisenbruch, M; Jayaswal, A; Maayan, N; Quraishi, SN; Rathbone, J, 2015)
"To compare depot fluphenazine medication to oral fluphenazine for treatment of schizophrenia."4.80Depot fluphenazine for schizophrenia. ( Adams, CE; Eisenbruch, M, 2000)
" This study aimed to report a case with bradycardia induced by fluphenazine decanoate administration."4.12Fluphenazine decanoate-induced bradycardia: A case report. ( Azizi, M; Elyasi, F; Kamali, M; Zarghami, M, 2022)
"We describe the case of a 39-year-old patient with schizophrenia who developed worsening of glucose metabolism during treatment with two different atypical antipsychotics, clozapine and quetiapine."3.73Importance of oral glucose tolerance test in patient with schizophrenia. ( Aukst-Margetić, B; Badanjak, A; Margetić, B, 2005)
"We examined the effect of age on psychopharmacological management in a naturalistic study of a group of 165 patients with a clinical diagnosis of schizophrenia or a related psychotic disorder (age range = 21-84 years; subjects > or = 1;45 years n = 86) treated with either haloperidol decanoate or fluphenazine decanoate."3.71The effect of age on the pharmacological management of ambulatory patients treated with depot neuroleptic medications for schizophrenia and related psychotic disorders. ( Chengappa, KN; Jeste, DV; Mamo, DC; Reddy, RR; Sweet, RA, 2002)
"Longitudinal assessment and management of the patient resulted in a diagnosis of schizophrenia and treatment with fluphenazine decanoate."3.69Intervention and social breakdown in the elderly. ( Little, JD, 1996)
"Plasma prolactin and fluphenazine concentrations were measured in a group of 17 patients (9 males, 8 females) with schizophrenia who were receiving chronic treatment with fluphenazine decanoate."3.67Plasma prolactin and fluphenazine concentrations in patients receiving fluphenazine decanoate: stability over injection intervals. ( Burrows, GD; Kimber, NM; Marriott, PF; Norman, TR, 1987)
"A patient with chronic schizophrenia treated with fluphenazine developed neuroleptic malignant syndrome, characterized by fever, obtundation, rigidity, and tremulousness."3.66Neuroleptic malignant syndrome: successful treatment with dantrolene and bromocriptine. ( Adler, S; Coyle, J; Granato, JE; Karim, AH; Krumholz, A; Ringel, A; Stern, BJ, 1983)
"Since schizophrenia is a common condition and treatment is usually long-term, this has important financial implications."2.69Generic substitution--comparing the clinical efficacy of a generic substitute for fluphenazine decanoate with the original product. ( Joubert, G; Stevens, M; van der Merwe, H; Verster, GC, 1998)
" Dosage data from the first 208 successfully-stabilized TSS subjects were examined."2.67Stabilization and depot neuroleptic dosages. ( Lee, JH; Schooler, NR; Schulz, SC; Severe, JB; Weiden, P, 1993)
" Results suggested an absorption half-life of 4 weeks, although, in three cases steady state was only achieved after 11 monthly injections."2.67Pharmacokinetics of haloperidol and fluphenazine decanoates in chronic schizophrenia. ( McCreadie, RG; Whitehead, A; Wiles, DH, 1990)
" Sixteen stable outpatients participated in a two-way crossover design study of the bioavailability of a new formulation of FPZ Dec, i."2.67The determination of the steady-state pharmacokinetic profile of fluphenazine decanoate by gas chromatography/mass spectrometry detection. ( Brown, WA; Friedhoff, LT; Glazer, WM; Marder, SR, 1992)
" The dosage equivalency of haloperidol decanoate (1."2.66A randomized clinical trial of haloperidol decanoate and fluphenazine decanoate in the outpatient treatment of schizophrenia. ( Annable, L; Campbell, W; Chouinard, G, 1989)
" When plasma levels from both dosage groups were combined, FLU at 12 weeks correlated significantly with factor scores for akinesia (r = 0."2.66Fluphenazine plasma levels in patients receiving low and conventional doses of fluphenazine decanoate. ( Hawes, EM; Hubbard, JW; Marder, SR; May, PR; McKay, G; Midha, KK; Mintz, J; Van Putten, T, 1986)
" There was no significant difference in survival when the clinician was permitted to make a dosage adjustment up to 10 mg in the low-dose group and 50 mg in the higher-dose group when the patient demonstrated evidence of a symptomatic exacerbation."2.66Low- and conventional-dose maintenance therapy with fluphenazine decanoate. Two-year outcome. ( Lebell, M; Marder, SR; May, PR; McKenzie, J; Mintz, J; Van Putten, T, 1987)
" The evidence available from prospective controlled trials suggests that substantial dosage reduction is feasible for a subgroup of outpatient schizophrenics and that the incidence of abnormal involuntary movements might be reduced by such a strategy."2.65Low dose medication strategies in the maintenance treatment of schizophrenia. ( Kane, JM, 1983)
" Maximum concentrations appeared at 1 week after administration of cis(Z)-clopenthixol decanoate, whereas the highest concentrations after fluphenazine decanoate were seen at the end of the 3-week dosage interval."2.65Blood and plasma kinetics of cis(Z)-clopenthixol and fluphenazine in psychiatric patients after intramuscular injection of their decanoic esters. ( Ba, B; Berda, C; D'Agostino, N; Dufour, H; Durand, A; Hou, N; Jørgensen, A; Viala, A, 1984)
" In addition, the clinician should consider the dosage schedule of each medication and balance this against the probability of extrapyramidal side effects and noncompliance."2.38Dose response of prophylactic antipsychotics. ( Brauzer, B; Casey, DE; Davis, JM; Gierl, B; Hassan, M; Kane, JM; Marder, SR; Schooler, N, 1993)
"9% of the total antipsychotic dosage on average."1.39Ten year outcomes of outpatients with schizophrenia on conventional depot antipsychotics: a systematic chart review. ( Den, R; Mimura, M; Sakurai, H; Suzuki, T; Tsutsumi, C; Uchida, H; Uchida, T, 2013)
"Schizophrenia is thought to be the psychiatric diagnosis the most frequently associated with TD."1.39[Tardive dyskinesia induced by classical antipsychotic drugs: a Tunisian sample of schizophrenics]. ( Bellaaj, R; Bouguerra, C; Gallali, S; Mehdi, F; Oumaya, A; Sejil, I, 2013)
"Schizophrenia Care and Assessment Program, a large, prospective study of treatment for schizophrenia conducted July 1997 through September 2003."1.34Characteristics and use patterns of patients taking first-generation depot antipsychotics or oral antipsychotics for schizophrenia. ( Ascher-Svanum, H; Faries, D; Marder, SR; Montgomery, W; Shi, L; Zhu, B, 2007)
" The average dosage was 251."1.30Age at onset of schizophrenia and neuroleptic dosage. ( Dernovsek, MZ; Tavcar, R, 1999)
"Treatment of schizophrenia is often complicated by substance abuse."1.30Alcohol dependence and hospitalization in schizophrenia. ( Arana, GW; Gerding, LB; Labbate, LA; Measom, MO; Santos, AB, 1999)
"Fluphenazine was significantly effective in treating symptoms such as emotional withdrawal, blunted affect, suspiciousness, thought disturbances, but not hallucinations."1.28Clinical and toxicological profile of fluphenazine decanoate in elderly chronic schizophrenia. ( Altamura, AC; Girardi, T; Mauri, MC; Panetta, B, 1990)
"The neuroleptic malignant syndrome is an exceedingly rare but potentially fatal condition characterized by parkinsonian type rigidity, rise of temperature and altered consciousness."1.28An unusual presentation of neuroleptic malignant syndrome. ( Basu, J, 1991)
"Seventeen outpatients were treated with depot neuroleptics, zuclopenthixol decanoate in Viscoleo or fluphenazine decanoate in sesame oil, with dosage intervals of 3 weeks."1.27Comparative study of the pharmacokinetics of zuclopenthixol decanoate and fluphenazine decanoate. ( Ba, B; Durand, A; Gouezo, F; Hou, N; Jørgensen, A; Viala, A, 1988)
"Haloperidol was given to 8 patients for 10 days (group A: 0."1.27Effects of neuroleptic treatments on peripheral opioid secretion. ( Bellodi, L; Brambilla, F; Brancato, V; Facchinetti, F; Genazzani, AR; Petraglia, F; Smeraldi, E, 1987)
" There were statistically significant tendencies for mean plasma fluphenazine levels to rise and mean plasma sulfoxide levels to fall over the 6-month period of study among patients on the high dose, consistent with our previously reported observation that it takes 3-6 months to establish a steady state of fluphenazine with this dosage regimen."1.27The sulfoxidation of fluphenazine in schizophrenic patients maintained on fluphenazine decanoate. ( Hawes, EM; Hubbard, JW; Marder, SR; May, PR; McKay, G; Midha, KK; Van Putten, T, 1987)
" Based on the study of plasma levels achieved with FPZ-D injection and oral FPZ-H (fluphenazine HC1) in 6 patients, the dosage requirement of FPZ-D appeared to be difficult to predict from the oral dosage of FPZ-H in the same patient."1.27Plasma levels of fluphenazine during fluphenazine decanoate treatment in schizophrenia. ( Casper, RC; Chang, SS; Davis, JM; Dysken, MW; Janicak, PG; Javaid, JI, 1985)
" To gather relevant data on pharmacokinetic characteristics of depot fluphenazines, the authors measured plasma levels of neuroleptic activity in 76 clinic patients on stable dosage regimens of fluphenazine decanoate or fluphenazine enanthate."1.27Plasma levels of neuroleptic in patients receiving depot fluphenazine. ( Chouinard, G; Cohen, BM; Jones, B; Sommer, BR; Waternaux, C, 1985)
"In 14 schizophrenic patients, prolactin levels are studied in relation to dosage of depot fluphenazine and gender of patient."1.27Depot fluphenazine and plasma prolactin. ( Gift, T; Plum, K; Price, M, 1985)
"281 newly admitted female schizophrenic patients were treated with high dosage fluphenazine decanoate intramuscularly, starting with 250 mg per injection together with antiparkinsonian and antidepressant drugs."1.26Follow-up study of 281 schizophrenic patients treated with high dosage fluphenazine decanoate. ( Nagy, C; Steiner, S, 1981)
"This high rate of relapse is viewed as indicating the need for continued medication in most chronic schizophrenic patients."1.26Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. ( Aderounmu, AF; Odejide, OA, 1982)

Research

Studies (199)

TimeframeStudies, this research(%)All Research%
pre-1990124 (62.31)18.7374
1990's52 (26.13)18.2507
2000's15 (7.54)29.6817
2010's7 (3.52)24.3611
2020's1 (0.50)2.80

Authors

AuthorsStudies
Kamali, M1
Zarghami, M1
Azizi, M1
Elyasi, F1
Kirk Morton, N1
Zubek, D1
Stanković, Z2
Ille, T2
Uchida, T1
Suzuki, T1
Sakurai, H1
Tsutsumi, C1
Den, R1
Mimura, M1
Uchida, H1
Maayan, N1
Quraishi, SN1
David, A1
Jayaswal, A1
Eisenbruch, M2
Rathbone, J1
Asher, R1
Adams, CE2
Rajarethinam, R1
Dziuba, J1
Manji, S1
Pizzuti, A1
Lachover, L1
Keshavan, M1
Citrome, L1
Jaffe, A1
Levine, J1
John, SM1
Venkatesan, S1
Tharyan, A1
Bhattacharji, S1
Sejil, I1
Oumaya, A1
Bouguerra, C1
Mehdi, F1
Bellaaj, R1
Gallali, S1
Mamo, DC1
Sweet, RA1
Chengappa, KN1
Reddy, RR1
Jeste, DV1
Conley, RR2
Kelly, DL2
Love, RC2
McMahon, RP1
Turner, M1
Eerdekens, E1
Jacko, M1
Eerdekens, M1
Margetić, B2
Aukst-Margetić, B1
Badanjak, A1
McEvoy, JP2
Baptista, T1
Martinez, M1
Lacruz, A1
Arellano, A1
Mendoza, S1
Beaulieu, S1
Hernández, L1
Contreras, Q1
Galeazzi, T1
Vargas, D1
Glazer, WM3
Shi, L1
Ascher-Svanum, H1
Zhu, B1
Faries, D1
Montgomery, W1
Marder, SR16
Aukst Margetić, B1
Small, JG1
Kellams, J1
Britvić, D1
Vuković, O1
Waddington, JL1
Gamble, SJ1
Chouinard, G4
Annable, L3
Ross-Chouinard, A1
Braddock, LE1
Blake, IM1
Balon, R1
Kabesh, Ia1
Papezhova, G1
Mandel, MR1
Severe, JB3
Schooler, NR3
Gelenberg, AJ1
Mieske, M1
van der Kolk, BA1
Goldberg, HL1
Walker, CA1
Johnson, DA1
Pasterski, G1
Ludlow, JM1
Street, K1
Taylor, RD1
Hogan, TP1
Awad, AG1
Lapierre, YD2
von Frenckell, R1
Müller, P1
Kane, JM7
Oyewumi, LK1
Gray, R1
Batth, S1
Gelfand, R1
Dencker, SJ1
Hogarty, GE3
Leff, J1
Kuipers, L1
Berkowitz, R1
Eberlein-Fries, R1
Sturgeon, D1
Ostow, M1
Viala, A2
Hou, N2
Ba, B2
Durand, A2
Dufour, H1
D'Agostino, N1
Berda, C1
Jørgensen, A2
Asarnow, RF2
Van Putten, T9
Rifkin, A5
Quitkin, F1
Nayak, D2
Ramos-Lorenzi, J2
Woerner, M2
Reardon, G2
Sarantakos, S1
Schiebel, D1
Wistedt, B3
Ranta, J1
McCreadie, RG3
McKane, JP2
Mackie, M2
Watt, DC1
Katz, K1
Shepherd, M1
Barnes, TR4
Milavic, G1
Curson, DA4
Platt, SD4
Campbell, W2
Boisvert, D1
Bradwejn, J1
Mintz, J10
McKenzie, J3
Lebell, M4
Faltico, G1
May, PR4
Michel, G1
Vásquez, R1
Basso, L1
Waldmann, KD1
Neumann, J1
Marriott, P1
Pansa, M1
Hiep, A1
Granato, JE1
Stern, BJ1
Ringel, A1
Karim, AH1
Krumholz, A1
Coyle, J2
Adler, S1
Palmstierna, T1
Ngui, PW1
Mattes, JA1
Perényi, A1
Arató, M1
Shear, MK1
Frances, A2
Weiden, P2
Gaby, N1
Lefkowitz, D1
Israel, JR1
Siris, SG12
Cooper, TB5
Rifkin, AE1
Brenner, R1
Lieberman, JA2
Polácek, J1
Odejide, OA1
Aderounmu, AF1
McCreadie, R1
Morrison, D1
Kidd, J1
Harris, PQ1
Friedman, MJ1
Cohen, BM2
Russell, N1
Landmark, J2
Merskey, H2
Turpin, T1
Steiner, S2
Filotto, JF1
Nagy, C1
Tan, CT1
Ong, TC1
Chee, KT1
Zhang, YF1
Tompson, MC1
Goldstein, MJ2
Lebell, MB1
Mintz, LI1
Goff, DC1
Midha, KK5
Sarid-Segal, O1
Hubbard, JW4
Amico, E1
Miller, RS1
Peterson, GM1
McLean, S1
Westhead, TT1
Gillies, P1
Ulrich, RF1
DiBarry, AL1
Bartone, P1
Cooley, S1
Hammill, K1
Carter, M1
Munetz, MR1
Perel, J1
Gall, JA1
Drummer, OH1
Landgren, AJ1
Bermanzohn, PC1
Mason, SE2
Shuwall, MA1
Inderbitzin, LB3
Lewine, RR2
Scheller-Gilkey, G2
Swofford, CD2
Egan, GJ1
Gloersen, BA2
Vidanagama, BP2
Waternaux, C2
Soni, SD4
Gaskell, K1
Reed, P1
Cernovsky, ZZ1
Davis, JM2
Brauzer, B1
Gierl, B1
Schooler, N1
Casey, DE1
Hassan, M1
Lee, JH1
Schulz, SC2
Stone, AM1
Greenstein, RA1
Gamble, G2
McLellan, AT1
de Nesnera, AP1
Heresco-Levy, U3
Greenberg, D3
Lerer, B3
Dasberg, H2
Brown, WA4
Robinson, D2
Woerner, MG2
Pollack, S1
Lerner, G1
Hawton, K1
Ware, C1
Mistry, H1
Hewitt, J1
Kingsbury, S1
Roberts, D1
Weitzel, H1
Kasckow, JW1
Little, JD1
Spivak, B1
Gonen, N1
Mester, R1
Averbuch, E1
Adlersberg, S1
Weizman, A1
Wirshing, WC3
Johnston, K1
Eckman, TA1
Zimmerman, K1
Liberman, RP1
Dhopesh, V1
Macfadden, A1
Maany, I1
Keith, SJ1
Matthews, SM1
Bellack, AS1
Glick, ID2
Hargreaves, WA1
Ninan, PT2
Jacobs, M2
Mance, R1
Simpson, GM2
Javitt, DC1
Verster, GC1
Joubert, G1
Stevens, M1
van der Merwe, H1
Yee, CM2
Nuechterlein, KH4
Morris, SE1
White, PM1
Moore, DB1
Sherr, JD1
Carpenter, WT1
Buchanan, RW1
Kirkpatrick, B1
Lann, HD1
Breier, AF1
Summerfelt, AT1
Thompson, PA1
Weiden, PJ1
Yadalam, K1
Odbert, CL1
Gerding, LB1
Labbate, LA1
Measom, MO1
Santos, AB1
Arana, GW1
Dernovsek, MZ1
Tavcar, R1
Linn, GS1
Lifshitz, K1
O'Keeffe, RT1
Lee, K1
Camp-Lifshitz, J1
Gitlin, M4
Nuechterlein, K2
Subotnik, KL1
Ventura, J3
Fogelson, DL1
Bartzokis, G1
Aravagiri, M4
Wirshing, DA1
Hoencamp, E1
Haffmans, PJ1
Jansen, GS1
Sampath, G1
Shah, A1
Krska, J1
Bergen, J1
Kitchin, R1
Berry, G1
Sachdev, P2
Tang, WM1
Dawson, ME2
Snyder, KS2
Hardesty, JP1
Friedhoff, LT1
McClelland, HA1
Metcalfe, AV1
Kerr, TA1
Dutta, D1
Watson, P1
Chabert, N1
Samuel, G1
Hawes, EM3
McKay, G3
Brownlee, M1
Ushakov, IuV2
Kravchenko, NE2
Kopeĭko, GI1
Kalugina, LI1
Mirzoian, MG1
Basu, J1
Altamura, AC3
Mauri, MC2
Girardi, T1
Panetta, B1
Durst, P1
Schuff, N1
Crocq, MA1
Mokrani, MC1
Macher, JP1
Commander, M1
Dean, C1
Geller, J1
Gingerich, S1
Wiles, DH3
Whitehead, A1
Clovis, WL1
Rosen, PB1
McDonald, SC1
Jann, MW2
Fidone, GS1
Hernandez, JM1
Amrung, S1
Davis, CM2
Faraone, SV1
Green, AI1
Brown, W1
Yin, P1
Tsuang, MT1
Wittman, L1
Leong, OK1
Wong, KE1
Tay, WK1
Gill, RC1
Neehall, J1
Aronson, A3
Sellew, AP2
Kong, DS2
Yeo, SH2
Hirsch, SR4
Jolley, AG1
Cooper, SJ1
Doherty, MM1
King, DJ1
Adan, F4
Filip, V2
Faltus, F1
Hanáková, S1
Janecková, E1
Raboch, J1
Dobiásová, A1
Karen, P1
Posmurová, M1
Borenstein, M2
Smulevich, AB1
Vorob'ev, VIu1
Dubnitskaia, EB1
Maksimov, VI1
Novikov, VN1
Teicher, MH1
Baldessarini, RJ1
Kolakowska, T2
Williams, AO2
Ardern, M2
Lazarus, A1
Reveley, MA1
Niss, AI1
Shibakova, TL1
Carotti, P1
Merli, R1
David, I1
Hellerová, P1
Fombonne, E1
Peron-Magnan, P1
Fuhrer, R1
Simon, P1
Dinan, TG1
Bartkó, G1
Herczeg, I1
Zádor, G1
Gouezo, F1
Brambilla, F1
Facchinetti, F1
Petraglia, F1
Smeraldi, E1
Bellodi, L1
Brancato, V1
Genazzani, AR1
Boza, RA1
Milanes, F1
Starkey, T1
Slater, V1
Dominguez, F1
Zimmerman, KE1
Cohen, M2
Mandeli, J3
Casey, E3
Guercetti, G1
Cazzullo, CL1
Klein, A1
Ehle, G1
Kitamura, T1
McGovern, DA1
Imlah, NW1
Wiles, D2
Schiff, AA2
Strahan, A2
Bamrah, JS1
Frechen, K1
Mandell, J1
Robinson, AD1
Stirling, GS1
Lee, A1
Gitlin, MJ1
Fogelson, D2
Kreisman, D1
Blumenthal, R1
Kane, J1
Yadalam, KG1
Turbott, J1
Villiger, J1
Hunter, L1
Irwin, M1
Fuentenebro, F1
Yuwiler, A1
Ereshefsky, L1
Saklad, SR1
Cookson, JC1
Kennedy, NM1
Gribbon, D1
Morgan, V1
Fagerstrom, R1
Anderson, CM1
Reiss, DJ1
Fasano-Dube, B1
Cassino, T1
Spellman, N1
Heiman, J1
Shupe, J1
Sklebar, HT1
Norman, TR1
Marriott, PF1
Kimber, NM1
Burrows, GD1
Jayaram, G1
Tune, L1
Blum, A1
Rappe, S1
Lesch, OM1
Dietzel-Rogan, M1
Musalek, M1
Rajna, P1
Rustembegovich, A1
Schjerve, M1
Walter, H1
Bamber, RW3
Duffy, JC3
Curry, SH1
Montgomery, S1
Chang, SS1
Javaid, JI1
Dysken, MW1
Casper, RC1
Janicak, PG1
Hinterhuber, H1
Neumann, R1
Reardon, GT1
Doddi, SR1
Hall, KS1
Silver, MA1
Kissling, W1
Möller, HJ1
Walter, K1
Wittmann, B1
Krueger, R1
Trenk, D1
Rapisarda, V1
Bonomo, V1
Parisi, R1
Sommer, BR1
Jones, B1
Gift, T1
Plum, K1
Price, M1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Alterations in mRNA and Protein Expression in Human Peripheral Mononuclear Blood Cells (PMC) of Schizophrenia Patients Treated With Fluvoxamine Augmentation of Antipsychotics: Relationship to Clinical Symptoms and Cognitive Function[NCT00645580]15 participants (Anticipated)Interventional2008-04-30Active, not recruiting
Pharmacological Approach to Improve the Outcome of Social Cognition Training[NCT01517360]Phase 127 participants (Actual)Interventional2012-01-31Completed
MAintain the Efficacy and Safety in Treatment of Schizophrenia After Switching to Long-acTing Injectable aRipiprazole From Oral Atypical Antipsychotics[NCT03376763]Phase 4201 participants (Actual)Interventional2017-11-21Completed
A Double-Blind, Placebo-Controlled Trial of Rosiglitazone for Clozapine Induced Glucose Metabolism Impairment: Bergman's Minimal Model Analysis[NCT00337350]Phase 420 participants (Actual)Interventional2003-09-30Completed
An Open Label Trial of Ziprasidone as an Adjuvant for Clozapine- or Olanzapine-Associated Diabetes Mellitus or Impaired Fasting Glucose in Chronic Schizophrenia[NCT00351000]Phase 424 participants (Actual)Interventional2005-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Acute Insulin Response to Glucose (AIRG)

Acute insulin response to glucose (AIRG) was assessed using a Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT), performed at Baseline and at week 8 (study endpoint). Subjects in the Rosiglitazone treatment arm were compared to subjects in the placebo treatment arm on their change in SG between Baseline and week 8. AIRG was calculated from plasma glucose and serum insulin values using the MINMOD Millennium computer program. AIRG measures the acute(0-10 min) beta cell response to a glucose load calculated by the areas under the curve higher than basal insulin values. The AIRG was assessed as the incremental area under the curve (calculated by the trapezoid rule) from 0 to 10 min of the FSIVGTT. (NCT00337350)
Timeframe: baseline, week 8

InterventionUnits/mL per 10 minutes (Mean)
Rosiglitazone-151
Placebo19

Change From Baseline in Insulin Sensitivity

Insulin Sensitivity (IS) was assessed using a Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT), performed at Baseline and at week 8 (study endpoint). Subjects in the Rosiglitazone treatment arm were compared to subjects in the placebo treatment arm on their change in IS between Baseline and week 8. SI was calculated from plasma glucose and serum insulin values using the MINMOD Millennium computer program. SI represents the increase in net fractional glucose clearance rate per unit change in serum insulin concentration after the intravenous glucose load (microUnits/mL). (NCT00337350)
Timeframe: baseline, week 8

InterventionmicroUnits/mL (Mean)
Rosiglitazone3.2
Placebo0.4

Change From Baseline on Glucose Utilization (SG)

Glucose utilization (SG) was assessed using a Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT), performed at Baseline and at week 8 (study endpoint). Subjects in the Rosiglitazone treatment arm were compared to subjects in the placebo treatment arm on their change in SG between Baseline and week 8. SG was calculated from plasma glucose and serum insulin values using the MINMOD Millennium computer program. SG represents the net fractional glucose clearance rate because of the increase in glucose independent of any increase in circulating insulin concentrations above baseline. (NCT00337350)
Timeframe: baseline, week 8

Interventionmin^-1 (Mean)
Rosiglitazone.002
Placebo-0.01

Change From Baseline in Fasting Glucose

Subjects on clozapine with adjunctive ziprasidone were compared to subjects on olanzapine with adjunctive ziprasidone on change in fasting glucose levels from baseline to study endpoint (week 6 - baseline) (NCT00351000)
Timeframe: baseline, week 6

Interventionmg/dL (Mean)
Clozapine Treatment With Adjunctive Ziprasidone5
Olanzapine Treatment With Adjunctive Ziprasidone-4.5

Change From Baseline on Fasting Insulin

Subjects on clozapine with adjunctive ziprasidone were compared to subjects on olanzapine with adjunctive ziprasidone on change in fasting insulin levels from baseline to study endpoint (week 6 - baseline) (NCT00351000)
Timeframe: baseline, week 6

InterventionmicroIU/L (Mean)
Clozapine Treatment With Adjunctive Ziprasidone1
Olanzapine Treatment With Adjunctive Ziprasidone-0.9

Reviews

8 reviews available for fluphenazine depot and Schizophrenia

ArticleYear
Fluphenazine decanoate (depot) and enanthate for schizophrenia.
    The Cochrane database of systematic reviews, 2015, Feb-05, Issue:2

    Topics: Administration, Oral; Antipsychotic Agents; Delayed-Action Preparations; Fluphenazine; Humans; Injec

2015
Risks versus benefits of different types of long-acting injectable antipsychotics.
    The Journal of clinical psychiatry, 2006, Volume: 67 Suppl 5

    Topics: Administration, Oral; Antipsychotic Agents; Fluphenazine; Haloperidol; Health Care Costs; Humans; In

2006
Depot fluphenazine: risk/benefit ratio.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:5 Pt 2

    Topics: Administration, Oral; Basal Ganglia Diseases; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Fe

1984
The use of depot neuroleptics: clinical experience in the United States.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:5 Pt 2

    Topics: Administration, Oral; Adult; Clinical Trials as Topic; Depressive Disorder; Drug Administration Sche

1984
Dose response of prophylactic antipsychotics.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Administration, Oral; Aftercare; Antipsychotic Agents; Combined Modality Therapy; Delayed-Action Pre

1993
Depot fluphenazine for schizophrenia.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Antipsychotic Agents; Delayed-Action Preparations; Fluphenazine; Humans; Schizophrenia

2000
Neuroleptic plasma levels.
    Schizophrenia bulletin, 1991, Volume: 17, Issue:2

    Topics: Antipsychotic Agents; Biological Availability; Chlorpromazine; Fluphenazine; Haloperidol; Humans; Pe

1991
Low-dose treatment strategies.
    The Journal of clinical psychiatry, 1986, Volume: 47 Suppl

    Topics: Adult; Ambulatory Care; Antipsychotic Agents; Clinical Trials as Topic; Dose-Response Relationship,

1986

Trials

73 trials available for fluphenazine depot and Schizophrenia

ArticleYear
Long-acting injectable risperidone: safety and efficacy in stable patients switched from conventional depot antipsychotics.
    International clinical psychopharmacology, 2004, Volume: 19, Issue:4

    Topics: Adult; Antipsychotic Agents; Clopenthixol; Delayed-Action Preparations; Dose-Response Relationship,

2004
Insulin resistance index and counter-regulatory factors during olanzapine or risperidone administration in subjects with schizophrenia.
    Schizophrenia research, 2007, Volume: 89, Issue:1-3

    Topics: Adult; Antipsychotic Agents; Appetite; Benzodiazepines; Blood Glucose; Chronic Disease; Delayed-Acti

2007
Fluphenazine enanthate and fluphenazine decanoate in the treatment of schizophrenic outpatients: extrapyramidal symptoms and therapeutic effect.
    The American journal of psychiatry, 1982, Volume: 139, Issue:3

    Topics: Adult; Ambulatory Care; Antipsychotic Agents; Basal Ganglia Diseases; Clinical Trials as Topic; Doub

1982
Development and prediction of postpsychotic depression in neuroleptic-treated schizophrenics.
    Archives of general psychiatry, 1982, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Antipsychotic Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind

1982
A double-blind comparative trial of the decanoates of clopenthixol and fluphenazine in the treatment of chronic schizophrenic out-patients.
    Pharmatherapeutica, 1983, Volume: 3, Issue:5

    Topics: Antipsychotic Agents; Chronic Disease; Clinical Trials as Topic; Clopenthixol; Delayed-Action Prepar

1983
Low dose medication strategies in the maintenance treatment of schizophrenia.
    Schizophrenia bulletin, 1983, Volume: 9, Issue:4

    Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Re

1983
Depot neuroleptics: the relevance of psychosocial factors--a United States perspective.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:5 Pt 2

    Topics: Antipsychotic Agents; Attitude to Health; Behavior Therapy; Clinical Trials as Topic; Family; Family

1984
Psychosocial relevance and benefit of neuroleptic maintenance: experience in the United Kingdom.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:5 Pt 2

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Attitude to Health; Clinical Trials as Topic; Delayed

1984
Blood and plasma kinetics of cis(Z)-clopenthixol and fluphenazine in psychiatric patients after intramuscular injection of their decanoic esters.
    Psychopharmacology, 1984, Volume: 83, Issue:2

    Topics: Adult; Antipsychotic Agents; Clopenthixol; Delayed-Action Preparations; Fluphenazine; Humans; Inject

1984
Fluphenazine vs placebo in patients with remitted, acute first-episode schizophrenia.
    Archives of general psychiatry, 1982, Volume: 39, Issue:1

    Topics: Adult; Aftercare; Double-Blind Method; Female; Fluphenazine; Humans; Male; Psychiatric Status Rating

1982
Low-dose neuroleptic treatment of outpatient schizophrenics. I. Preliminary results for relapse rates.
    Archives of general psychiatry, 1983, Volume: 40, Issue:8

    Topics: Adult; Ambulatory Care; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule;

1983
Comparative double-blind study of flupenthixol decanoate and fluphenazine decanoate in the treatment of patients relapsing in a schizophrenic symptomatology.
    Acta psychiatrica Scandinavica, 1983, Volume: 67, Issue:6

    Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Depression; Double-Blind Method; Flupenthixo

1983
Weekly pimozide versus fluphenazine decanoate in schizophrenic out-and day-patients.
    The British journal of psychiatry : the journal of mental science, 1983, Volume: 143

    Topics: Clinical Trials as Topic; Double-Blind Method; Female; Fluphenazine; Humans; Male; Pimozide; Schizop

1983
The natural history of schizophrenia: a 5-year prospective follow-up of a representative sample of schizophrenics by means of a standardized clinical and social assessment.
    Psychological medicine, 1983, Volume: 13, Issue:3

    Topics: Clinical Trials as Topic; Female; Fluphenazine; Follow-Up Studies; Humans; Male; Patient Readmission

1983
Use of the Social Behaviour Assessment Schedule (SBAS) in a trial of maintenance antipsychotic therapy in schizophrenic outpatients: pimozide versus fluphenazine.
    Social psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 1983, Volume: 18, Issue:4

    Topics: Adult; Clinical Trials as Topic; Female; Fluphenazine; Humans; Male; Middle Aged; Outpatients; Pimoz

1983
Depot fluphenazine: risk/benefit ratio.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:5 Pt 2

    Topics: Administration, Oral; Basal Ganglia Diseases; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Fe

1984
The use of depot neuroleptics: clinical experience in the United States.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:5 Pt 2

    Topics: Administration, Oral; Adult; Clinical Trials as Topic; Depressive Disorder; Drug Administration Sche

1984
A double-blind, controlled clinical trial of haloperidol decanoate and fluphenazine decanoate in the maintenance treatment of schizophrenia.
    Psychopharmacology bulletin, 1984,Winter, Volume: 20, Issue:1

    Topics: Clinical Trials as Topic; Double-Blind Method; Female; Fluphenazine; Haloperidol; Humans; Male; Schi

1984
Costs and benefits of two doses of fluphenazine.
    Archives of general psychiatry, 1984, Volume: 41, Issue:11

    Topics: Adult; Clinical Trials as Topic; Cost-Benefit Analysis; Double-Blind Method; Drug Administration Sch

1984
Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:10

    Topics: Adult; Depressive Disorder; Double-Blind Method; Female; Flupenthixol; Fluphenazine; Humans; Male; P

1983
A placebo-controlled trial of fluoxetine added to neuroleptic in patients with schizophrenia.
    Psychopharmacology, 1995, Volume: 117, Issue:4

    Topics: Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Fluphenazine; Haloperidol; Human

1995
Pharmacotherapy of impaired affect in recovering schizophrenic patients.
    Archives of general psychiatry, 1995, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Ambulatory Care; Antipsychotic Agents; Anxiety Disorders; Basal Ganglia Diseases;

1995
Maintenance imipramine therapy for secondary depression in schizophrenia. A controlled trial.
    Archives of general psychiatry, 1994, Volume: 51, Issue:2

    Topics: Adult; Antipsychotic Agents; Benztropine; Delayed-Action Preparations; Depressive Disorder; Double-B

1994
A double-blind dose-reduction trial of fluphenazine decanoate for chronic, unstable schizophrenic patients.
    The American journal of psychiatry, 1994, Volume: 151, Issue:12

    Topics: Adult; Ambulatory Care; Basal Ganglia Diseases; Chronic Disease; Delayed-Action Preparations; Double

1994
Fluphenazine treatment of DSM-III-R male schizophrenic patients among the Xhosa.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1994, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Ethnicity; Fluphenazine; Humans; Length of Stay; Male; Middle Aged; Psychiatric S

1994
Stabilization and depot neuroleptic dosages.
    Psychopharmacology bulletin, 1993, Volume: 29, Issue:2

    Topics: Adult; Delayed-Action Preparations; Fluphenazine; Humans; Male; Schizophrenia

1993
Subject selection biases in clinical trials: data from a multicenter schizophrenia treatment study.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:2

    Topics: Acute Disease; Adult; Clinical Trials as Topic; Combined Modality Therapy; Data Interpretation, Stat

1996
Paracetamol self-poisoning. Characteristics, prevention and harm reduction.
    The British journal of psychiatry : the journal of mental science, 1996, Volume: 168, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Delayed-Action Preparation

1996
Substance use: a powerful predictor of relapse in schizophrenia.
    Schizophrenia research, 1996, Volume: 20, Issue:1-2

    Topics: Adult; Antipsychotic Agents; Comorbidity; Diagnosis, Dual (Psychiatry); Dose-Response Relationship,

1996
Two-year outcome of social skills training and group psychotherapy for outpatients with schizophrenia.
    The American journal of psychiatry, 1996, Volume: 153, Issue:12

    Topics: Adult; Age of Onset; Ambulatory Care; Behavior Therapy; Combined Modality Therapy; Fluphenazine; Hum

1996
Relapse and rehospitalization during maintenance treatment of schizophrenia. The effects of dose reduction and family treatment.
    Archives of general psychiatry, 1997, Volume: 54, Issue:5

    Topics: Adolescent; Adult; Ambulatory Care; Combined Modality Therapy; Delayed-Action Preparations; Dose-Res

1997
Serum neuroleptic levels during reduced dose fluphenazine decanoate maintenance therapy.
    The Israel journal of psychiatry and related sciences, 1997, Volume: 34, Issue:4

    Topics: Adult; Chronic Disease; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Fluph

1997
Generic substitution--comparing the clinical efficacy of a generic substitute for fluphenazine decanoate with the original product.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1998, Volume: 88, Issue:3

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Delayed-Action Preparations; Double-Blind Method; Dru

1998
P50 suppression in recent-onset schizophrenia: clinical correlates and risperidone effects.
    Journal of abnormal psychology, 1998, Volume: 107, Issue:4

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Anxiety; Attention; Cognition; Depression; Evoked

1998
Comparative effectiveness of fluphenazine decanoate injections every 2 weeks versus every 6 weeks.
    The American journal of psychiatry, 1999, Volume: 156, Issue:3

    Topics: Adult; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Fluph

1999
Lithium augmentation fails to reduce symptoms in poorly responsive schizophrenic outpatients.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:6

    Topics: Ambulatory Care; Brief Psychiatric Rating Scale; Drug Therapy, Combination; Fluphenazine; Humans; Li

1999
Clinical outcome following neuroleptic discontinuation in patients with remitted recent-onset schizophrenia.
    The American journal of psychiatry, 2001, Volume: 158, Issue:11

    Topics: Adolescent; Adult; Antipsychotic Agents; Cross-Over Studies; Double-Blind Method; Fluphenazine; Foll

2001
Fluphenazine plasma level monitoring for patients receiving fluphenazine decanoate.
    Schizophrenia research, 2002, Jan-01, Volume: 53, Issue:1-2

    Topics: Adult; Dose-Response Relationship, Drug; Drug Monitoring; Female; Fluphenazine; Humans; Male; Middle

2002
Developmental Processes in Schizophrenic Disorders: longitudinal studies of vulnerability and stress.
    Schizophrenia bulletin, 1992, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Attitude to Health; Autonomic Nervous System; Double-Blind Method; Female; Fluphe

1992
Developmental Processes in Schizophrenic Disorders: longitudinal studies of vulnerability and stress.
    Schizophrenia bulletin, 1992, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Attitude to Health; Autonomic Nervous System; Double-Blind Method; Female; Fluphe

1992
Developmental Processes in Schizophrenic Disorders: longitudinal studies of vulnerability and stress.
    Schizophrenia bulletin, 1992, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Attitude to Health; Autonomic Nervous System; Double-Blind Method; Female; Fluphe

1992
Developmental Processes in Schizophrenic Disorders: longitudinal studies of vulnerability and stress.
    Schizophrenia bulletin, 1992, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Attitude to Health; Autonomic Nervous System; Double-Blind Method; Female; Fluphe

1992
The determination of the steady-state pharmacokinetic profile of fluphenazine decanoate by gas chromatography/mass spectrometry detection.
    Schizophrenia research, 1992, Volume: 8, Issue:2

    Topics: Adult; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Flup

1992
Psychiatrists and citizens.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 159

    Topics: Chronic Disease; Double-Blind Method; Ethics, Medical; Fluphenazine; Humans; Informed Consent; Schiz

1991
Plasma levels of fluphenazine in patients receiving fluphenazine decanoate. Relationship to clinical response.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 158

    Topics: Adult; Akathisia, Drug-Induced; Delayed-Action Preparations; Dose-Response Relationship, Drug; Doubl

1991
[Clinical and economic approach to evaluation of the effectiveness of moditen-depot and haloperidol decanoate in the maintenance therapy of attack-like schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1990, Volume: 90, Issue:7

    Topics: Antipsychotic Agents; Cost-Benefit Analysis; Fluphenazine; Haloperidol; Humans; Remission Induction;

1990
Pharmacokinetics of haloperidol and fluphenazine decanoates in chronic schizophrenia.
    Psychopharmacology, 1990, Volume: 101, Issue:2

    Topics: Adult; Aged; Biological Availability; Double-Blind Method; Female; Fluphenazine; Half-Life; Haloperi

1990
A randomized clinical trial of haloperidol decanoate and fluphenazine decanoate in the outpatient treatment of schizophrenia.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Antipsychotic Agents; Clinical Trials as Topic; Delayed-Ac

1989
Neuroleptic dose reduction in persistently psychotic patients.
    Hospital & community psychiatry, 1989, Volume: 40, Issue:11

    Topics: Adult; Aged; Antipsychotic Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Fluph

1989
A comparative study of pipothiazine palmitate and fluphenazine decanoate in the maintenance of remission of schizophrenia.
    Singapore medical journal, 1989, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Delayed-Action Preparations; Female; Fluphenazine; Hu

1989
Imipramine-responsive panic-like symptomatology in schizophrenia/schizoaffective disorder.
    Biological psychiatry, 1989, Feb-15, Volume: 25, Issue:4

    Topics: Adult; Benztropine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Fear;

1989
An open clinical trial with the long-acting neuroleptics flupenthixol decanoate and fluphenazine decanoate in the maintenance treatment of schizophrenia.
    Pharmatherapeutica, 1989, Volume: 5, Issue:6

    Topics: Clinical Trials as Topic; Female; Flupenthixol; Fluphenazine; Humans; Male; Middle Aged; Psychiatric

1989
The dysphoric syndrome in schizophrenia and its implications for relapse.
    The British journal of psychiatry. Supplement, 1989, Issue:5

    Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluphenazine; Fol

1989
Tardive dystonia. The benefits of time.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 155

    Topics: Adult; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Dys

1989
[Oxyprothepin decanoate in maintenance therapy of schizophrenia--a double-blind, standardized controlled study].
    Ceskoslovenska psychiatrie, 1985, Volume: 81, Issue:1

    Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Dibenzothiepins; Double-Blind Method; Female;

1985
Low-dose treatment strategies.
    The Journal of clinical psychiatry, 1986, Volume: 47 Suppl

    Topics: Adult; Ambulatory Care; Antipsychotic Agents; Clinical Trials as Topic; Dose-Response Relationship,

1986
Comparative study of four evaluation criteria in a clinical trial with schizophrenic patients.
    Neuropsychobiology, 1986, Volume: 16, Issue:4

    Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Fluphenazine; Humans; Middle Aged; Nursing; P

1986
Differential effect of low and conventional doses of fluphenazine on schizophrenic outpatients with good or poor information-processing abilities.
    Archives of general psychiatry, 1988, Volume: 45, Issue:9

    Topics: Adult; Clinical Trials as Topic; Dose-Response Relationship, Drug; Fluphenazine; Humans; Male; Middl

1988
Postpsychotic depression and negative symptoms: an investigation of syndromal overlap.
    The American journal of psychiatry, 1988, Volume: 145, Issue:12

    Topics: Adolescent; Adult; Aged; Benztropine; Clinical Trials as Topic; Depressive Disorder; Double-Blind Me

1988
Fluphenazine plasma levels in patients receiving low and conventional doses of fluphenazine decanoate.
    Psychopharmacology, 1986, Volume: 88, Issue:4

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Fluphenazine; Humans; Kinetics; Male; Middle A

1986
Antidepressants in the treatment of post-psychotic depression in schizophrenia: drug interactions and other considerations.
    Clinical chemistry, 1988, Volume: 34, Issue:5

    Topics: Adult; Affective Disorders, Psychotic; Benztropine; Clinical Trials as Topic; Drug Interactions; Flu

1988
Haloperidol decanoate v. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients.
    The British journal of psychiatry : the journal of mental science, 1987, Volume: 151

    Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Fluphenazine; H

1987
Persistence of fluphenazine in plasma after decanoate withdrawal.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:1

    Topics: Adult; Female; Fluphenazine; Humans; Male; Radioimmunoassay; Schizophrenia; Substance Withdrawal Syn

1988
Family attitudes and patient social adjustment in a longitudinal study of outpatient schizophrenics receiving low-dose neuroleptics: the family's view.
    Psychiatry, 1988, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Attitude; Dose-Response Relationship, Drug; Family; Female; Fluphenazine; Humans;

1988
Bioavailability of psychotropic drugs: historical perspective and pharmacokinetic overview.
    The Journal of clinical psychiatry, 1986, Volume: 47 Suppl

    Topics: Biological Availability; Clinical Trials as Topic; Drug Evaluation; Fluphenazine; Humans; Kinetics;

1986
Weight gain and prolactin levels in patients on long-term antipsychotic medication: a double-blind comparative trial of haloperidol decanoate and fluphenazine decanoate.
    International clinical psychopharmacology, 1986, Volume: 1 Suppl 1

    Topics: Adult; Body Weight; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Fema

1986
A comparative trial of haloperidol decanoate and fluphenazine decanoate in chronic schizophrenic patients.
    International clinical psychopharmacology, 1986, Volume: 1 Suppl 1

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method;

1986
Adjunctive imipramine in the treatment of postpsychotic depression. A controlled trial.
    Archives of general psychiatry, 1987, Volume: 44, Issue:6

    Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination

1987
Low- and conventional-dose maintenance therapy with fluphenazine decanoate. Two-year outcome.
    Archives of general psychiatry, 1987, Volume: 44, Issue:6

    Topics: Adult; Akathisia, Drug-Induced; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Indu

1987
Targeted treatment of depression-like symptoms in schizophrenia.
    Psychopharmacology bulletin, 1987, Volume: 23, Issue:1

    Topics: Benztropine; Depression; Drug Therapy, Combination; Fluphenazine; Humans; Imipramine; Schizophrenia

1987
[Social integration of long-term paraphrenic patients with low-dose depot neuroleptic medication].
    Psychiatrische Praxis, 1985, Volume: 12, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Fluphenazine; Human

1985
Long-term depot maintenance of chronic schizophrenic out-patients: the seven year follow-up of the Medical Research Council fluphenazine/placebo trial I. Course of illness, stability of diagnosis, and the role of a special maintenance clinic.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 146

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method;

1985
Long-term depot maintenance of chronic schizophrenic out-patients: the seven year follow-up of the Medical Research Council fluphenazine/placebo trial. II. The incidence of compliance problems, side-effects, neurotic symptoms and depression.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 146

    Topics: Clinical Trials as Topic; Delayed-Action Preparations; Depressive Disorder; Double-Blind Method; Dys

1985
Long-term depot maintenance of chronic schizophrenic out-patients: the seven year follow-up of the Medical Research Council fluphenazine/placebo trial. III. Relapse postponement or relapse prevention? The implications for long-term outcome.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 146

    Topics: Clinical Trials as Topic; Delayed-Action Preparations; Fluphenazine; Follow-Up Studies; Humans; Recu

1985
Early unwanted effects of fluphenazine esters related to plasma fluphenazine concentrations in schizophrenic patients.
    Psychopharmacology, 1985, Volume: 87, Issue:1

    Topics: Adult; Female; Fluphenazine; Humans; Male; Middle Aged; Prolactin; Schizophrenia

1985
Double-blind comparison of haloperidol decanoate and fluphenazine decanoate effectiveness, side-effects, dosage and serum levels during a six months' treatment for relapse prevention.
    Pharmacopsychiatry, 1985, Volume: 18, Issue:3

    Topics: Adult; Double-Blind Method; Female; Fluphenazine; Haloperidol; Humans; Male; Middle Aged; Schizophre

1985

Other Studies

121 other studies available for fluphenazine depot and Schizophrenia

ArticleYear
Fluphenazine decanoate-induced bradycardia: A case report.
    Neuropsychopharmacology reports, 2022, Volume: 42, Issue:3

    Topics: Adult; Antipsychotic Agents; Bradycardia; Delayed-Action Preparations; Fluphenazine; Humans; Male; S

2022
Adherence challenges and long-acting injectable antipsychotic treatment in patients with schizophrenia.
    Journal of psychosocial nursing and mental health services, 2013, Volume: 51, Issue:3

    Topics: Antipsychotic Agents; Benzodiazepines; Delayed-Action Preparations; Fluphenazine; Haloperidol; Human

2013
Adherence to depot versus oral antipsychotic medication in schizophrenic patients during the long-term therapy.
    Vojnosanitetski pregled, 2013, Volume: 70, Issue:3

    Topics: Administration, Oral; Adult; Antipsychotic Agents; Delayed-Action Preparations; Female; Fluphenazine

2013
Ten year outcomes of outpatients with schizophrenia on conventional depot antipsychotics: a systematic chart review.
    International clinical psychopharmacology, 2013, Volume: 28, Issue:5

    Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Drug Combinations; Female; Fluphenazine; H

2013
Use of aripiprazole in tardive dyskinesia: an open label study of six cases.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 2

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Dose-Response Relationship, Drug; Drug Administration Sch

2009
Treatment of schizophrenia with depot preparations of fluphenazine, haloperidol, and risperidone among inpatients at state-operated psychiatric facilities.
    Schizophrenia research, 2010, Volume: 119, Issue:1-3

    Topics: Administration, Oral; Adult; Antipsychotic Agents; Delayed-Action Preparations; Dose-Response Relati

2010
The challenge of patients with severe psychiatric illness who do not access care - a way forward.
    Tropical doctor, 2010, Volume: 40, Issue:4

    Topics: Antipsychotic Agents; Community Mental Health Services; Female; Fluphenazine; Health Behavior; Healt

2010
[Tardive dyskinesia induced by classical antipsychotic drugs: a Tunisian sample of schizophrenics].
    L'Encephale, 2013, Volume: 39 Suppl 1

    Topics: Adult; Antipsychotic Agents; Cross-Sectional Studies; Delayed-Action Preparations; Dose-Response Rel

2013
The effect of age on the pharmacological management of ambulatory patients treated with depot neuroleptic medications for schizophrenia and related psychotic disorders.
    International journal of geriatric psychiatry, 2002, Volume: 17, Issue:11

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Delayed-Action Preparations; Dose

2002
Rehospitalization risk with second-generation and depot antipsychotics.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2003, Volume: 15, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Data Collection; Delayed-Action Preparation

2003
Importance of oral glucose tolerance test in patient with schizophrenia.
    Psychiatria Danubina, 2005, Volume: 17, Issue:1-2

    Topics: Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Fluphenazine; Glucose Tolerance T

2005
Who receives long-acting antipsychotic medications?
    Psychiatric services (Washington, D.C.), 2007, Volume: 58, Issue:4

    Topics: Antipsychotic Agents; Black People; Dangerous Behavior; Drug Utilization; Fluphenazine; Humans; Prej

2007
Characteristics and use patterns of patients taking first-generation depot antipsychotics or oral antipsychotics for schizophrenia.
    Psychiatric services (Washington, D.C.), 2007, Volume: 58, Issue:4

    Topics: Administration, Oral; Adult; Alcoholism; Antipsychotic Agents; Black People; Cohort Studies; Comorbi

2007
Switching as only temporal solution for patients with antipsychotic-associated diabetes: further observations.
    Psychiatria Danubina, 2007, Volume: 19, Issue:1-2

    Topics: Adult; Antipsychotic Agents; Blood Glucose; Body Mass Index; Clozapine; Diabetes Mellitus, Type 2; D

2007
Early hospital experience with fluphenazine decanoate.
    Diseases of the nervous system, 1974, Volume: 35, Issue:10

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Drug Administration Schedule; Female; Fluphenazine; Fo

1974
Treatment compliance of outpatients with schizophrenia: patient's attitudes, demographic, clinical and therapeutic variables.
    Psychiatria Danubina, 2008, Volume: 20, Issue:1

    Topics: Administration, Oral; Adult; Age Factors; Ambulatory Care; Antipsychotic Agents; Clozapine; Cross-Se

2008
Prolonged dopamine receptor blockade in rats after termination of long-term depot fluphenazine.
    Lancet (London, England), 1981, Jun-20, Volume: 1, Issue:8234

    Topics: Animals; Delayed-Action Preparations; Fluphenazine; Humans; Male; Rats; Receptors, Dopamine; Schizop

1981
Neuroendocrine tests during treatment with neuroleptic drugs. II. The TRH test.
    The British journal of psychiatry : the journal of mental science, 1981, Volume: 139

    Topics: Adult; Aged; Antipsychotic Agents; Delayed-Action Preparations; Female; Flupenthixol; Fluphenazine;

1981
[Comparison between the effectiveness of fluphenazine decanoate and oxyprothepin decanoate in schizophrenia (double-blind crossover study)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:1

    Topics: Adult; Antipsychotic Agents; Dibenzothiepins; Double-Blind Method; Female; Fluphenazine; Humans; Mal

1982
Aftercare of schizophrenic patients: pharmacotherapy and consistency of therapists.
    Hospital & community psychiatry, 1983, Volume: 34, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Aftercare; Antipsychotic Agents; Fluphenazine; Follow-Up St

1983
The discontinuance of maintenance neuroleptic therapy in chronic schizophrenic patients: drug and social consequences.
    Acta psychiatrica Scandinavica, 1983, Volume: 67, Issue:5

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Drug Administration Schedule; Female; Flupenthixol; Fl

1983
Pharmacotherapy and suicide risk in schizophrenia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1983, Volume: 28, Issue:4

    Topics: Adult; Antipsychotic Agents; Depressive Disorder; Drug Therapy, Combination; Female; Fluphenazine; H

1983
AMDP psychopathology factors in chronic schizophrenia: a clinical trial of two long-acting neuroleptics.
    Modern problems of pharmacopsychiatry, 1983, Volume: 20

    Topics: Adolescent; Adult; Antipsychotic Agents; Chronic Disease; Female; Fluphenazine; Humans; Male; Middle

1983
[What should we recommend for schizophrenic patients: long-term drug prevention or interval treatment?].
    Der Nervenarzt, 1983, Volume: 54, Issue:9

    Topics: Ambulatory Care; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Drug Administration Sch

1983
Abnormal involuntary movements in patients on long-acting neuroleptics.
    Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:4-6

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cross-Sectional Studies; Dose-Response Relationship,

1983
The risk/benefit ratio of depot neuroleptics: a Scandinavian perspective.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:5 Pt 2

    Topics: Administration, Oral; Antipsychotic Agents; Basal Ganglia Diseases; Biological Availability; Chronic

1984
Standard v optimal dose.
    Archives of general psychiatry, 1984, Volume: 41, Issue:7

    Topics: Ambulatory Care; Antipsychotic Agents; Drug Administration Schedule; Fluphenazine; Humans; Schizophr

1984
Information processing and neuroleptic response in acute and stabilized schizophrenic patients.
    Psychiatry research, 1984, Volume: 13, Issue:1

    Topics: Adult; Antipsychotic Agents; Cognition; Fluphenazine; Haloperidol; Humans; Male; Pattern Recognition

1984
[Follow-up study of patients treated with depot phenothiazines in Valparaiso, Chile].
    Boletin de la Oficina Sanitaria Panamericana. Pan American Sanitary Bureau, 1981, Volume: 91, Issue:5

    Topics: Adolescent; Adult; Aged; Chile; Female; Fluphenazine; Follow-Up Studies; Humans; Male; Mental Disord

1981
[Clinical experience with depot neuroleptic treatment].
    Zeitschrift fur arztliche Fortbildung, 1984, Volume: 78, Issue:20

    Topics: Female; Fluphenazine; Hallucinations; Humans; Male; Prognosis; Psychotic Disorders; Schizophrenia; S

1984
Intervals between long acting neuroleptics: outcome and re-admission variables.
    Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:1

    Topics: Age Factors; Chronic Disease; Female; Fluphenazine; Follow-Up Studies; Humans; Male; Patient Readmis

1984
Neuroleptic malignant syndrome: successful treatment with dantrolene and bromocriptine.
    Annals of neurology, 1983, Volume: 14, Issue:1

    Topics: Adult; Basal Ganglia Diseases; Bromocriptine; Dantrolene; Drug Therapy, Combination; Fluphenazine; H

1983
[Clinical significance of depot fluphenazine decanoate in therapy of acute psychotic disorders].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1983, Volume: 85, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Bipolar Disorder; Delayed-Action Preparations; Female; Fluph

1983
Lithium versus fluphenazine for prophylaxis in mainly schizophrenic schizo-affectives.
    Biological psychiatry, 1984, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Double-Blind Method; Drug Therapy, Combination; Fluphenazine; Humans; Lithium; Mi

1984
Fluphenazine and tardive dyskinesia.
    Archives of general psychiatry, 1984, Volume: 41, Issue:7

    Topics: Delayed-Action Preparations; Drug Administration Schedule; Dyskinesia, Drug-Induced; Fluphenazine; H

1984
Suicide associated with akathisia and depot fluphenazine treatment.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:4

    Topics: Adult; Akathisia, Drug-Induced; Dyskinesia, Drug-Induced; Fluphenazine; Humans; Male; Psychomotor Ag

1983
Experience with fluphenazine decanoate in the management of chronic schizophrenic outpatients.
    North Carolina medical journal, 1982, Volume: 43, Issue:9

    Topics: Adult; Ambulatory Care; Delayed-Action Preparations; Female; Fluphenazine; Follow-Up Studies; Humans

1982
Plasma imipramine concentrations in patients receiving concomitant fluphenazine decanoate.
    The American journal of psychiatry, 1982, Volume: 139, Issue:1

    Topics: Adult; Delayed-Action Preparations; Depression; Drug Interactions; Drug Therapy, Combination; Female

1982
[Treatment of schizophrenic psychoses by sustained-action neuroleptics in psychiatric outpatients' treatment (author's transl)].
    Ceskoslovenska psychiatrie, 1982, Volume: 78, Issue:1

    Topics: Adult; Aged; Ambulatory Care; Delayed-Action Preparations; Female; Fluphenazine; Humans; Male; Middl

1982
Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:5

    Topics: Chronic Disease; Delayed-Action Preparations; Double-Blind Method; Fluphenazine; Humans; Psychiatric

1982
Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia.
    The British journal of psychiatry : the journal of mental science, 1982, Volume: 140

    Topics: Adult; Aged; Chronic Disease; Double-Blind Method; Dyskinesia, Drug-Induced; Fluphenazine; Humans; M

1982
Fluphenazine blood levels and clinical response.
    Biological psychiatry, 1982, Volume: 17, Issue:10

    Topics: Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Fluphenazine; Humans; Radiol

1982
A double-blind comparison of fluspirilene and fluphenazine decanoate in schizophrenia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1982, Volume: 27, Issue:7

    Topics: Adult; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Fluphenazine; Fluspirilene; Humans; Ma

1982
[Modification of schizophrenia by intensive neuroleptic therapy and the course of the disease after withdrawal of neuroleptic drugs].
    Psychiatria clinica, 1980, Volume: 13, Issue:3-4

    Topics: Adolescent; Adult; Aged; Child; Drug Administration Schedule; Fluphenazine; Follow-Up Studies; Human

1980
[Group psychotherapy of chronic schizophrenics in an external milieu].
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1981, Volume: 26, Issue:8

    Topics: Adult; Ambulatory Care; Chronic Disease; Female; Fluphenazine; Humans; Male; Middle Aged; Psychoanal

1981
Follow-up study of 281 schizophrenic patients treated with high dosage fluphenazine decanoate.
    International pharmacopsychiatry, 1981, Volume: 16, Issue:3

    Topics: Age Factors; Dyskinesia, Drug-Induced; Female; Fluphenazine; Follow-Up Studies; Humans; Recurrence;

1981
The use of fluphenazine decanoate (Modecate)depot therapy in outpatient schizophrenics-a retrospective study.
    Singapore medical journal, 1981, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Ambulatory Care; Child; Delayed-Action Preparations; Female; Fluphenazine; Humans

1981
[Clinical observation on the effect of domestic fluphenazine decanoate in the treatment of schizophrenia---report of 431 cases (author's transl)].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1981, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Fluphenazi

1981
Schizophrenic patients' perceptions of their relatives' attitudes.
    Psychiatry research, 1995, Jul-28, Volume: 57, Issue:2

    Topics: Adult; Affect; Antipsychotic Agents; Black or African American; Family; Fluphenazine; Humans; Middle

1995
Monitoring plasma levels of fluphenazine during chronic therapy with fluphenazine decanoate.
    Journal of clinical pharmacy and therapeutics, 1995, Volume: 20, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Delayed-Action Preparations; Dose-Response Relationship, Drug; Dr

1995
Death due to benzhexol toxicity.
    Forensic science international, 1995, Jan-21, Volume: 71, Issue:1

    Topics: Bronchopneumonia; Cause of Death; Death, Sudden; Dyskinesia, Drug-Induced; Empyema, Pleural; Fatal O

1995
Factors affecting rehospitalisation rates of chronic schizophrenic patients living in the community.
    Schizophrenia research, 1994, Volume: 12, Issue:2

    Topics: Adult; Aged; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Sche

1994
Cocaine use by schizophrenic outpatients who receive depot neuroleptic medication.
    Hospital & community psychiatry, 1993, Volume: 44, Issue:2

    Topics: Adult; Ambulatory Care; Chronic Disease; Cocaine; Combined Modality Therapy; Comorbidity; Delayed-Ac

1993
Diphenhydramine dependence: a need for awareness.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:3

    Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Diphenhydramine; Fluphenazine; Humans; Mal

1996
Two-year trial of maintenance neuroleptic dose reduction in schizophrenic out-patients: predictors of relapse.
    The Israel journal of psychiatry and related sciences, 1995, Volume: 32, Issue:4

    Topics: Adult; Ambulatory Care; Antipsychotic Agents; Dose-Response Relationship, Drug; Female; Fluphenazine

1995
Intervention and social breakdown in the elderly.
    The Australian and New Zealand journal of psychiatry, 1996, Volume: 30, Issue:5

    Topics: Aged; Combined Modality Therapy; Community Mental Health Services; Ethics, Medical; Female; Fluphena

1996
Neuroleptic malignant syndrome associated with abrupt withdrawal of anticholinergic agents.
    International clinical psychopharmacology, 1996, Volume: 11, Issue:3

    Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Fluphenazine; Humans; Male; Muscarinic Ant

1996
Absence of parkinsonism among patients in long-term neuroleptic therapy who abuse cocaine.
    Psychiatric services (Washington, D.C.), 1997, Volume: 48, Issue:1

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Cocaine; Comorbidity; Delayed-Action Preparations; Flu

1997
Rehospitalization rates for depot antipsychotics and pharmacoeconomic implications: comparison with risperidone.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, Dec-15, Volume: 55, Issue:24 Suppl 4

    Topics: Antipsychotic Agents; Baltimore; Chronic Disease; Delayed-Action Preparations; Disease-Free Survival

1998
Alcohol dependence and hospitalization in schizophrenia.
    Schizophrenia research, 1999, Jul-27, Volume: 38, Issue:1

    Topics: Adult; Alcoholism; Antipsychotic Agents; Cocaine-Related Disorders; Comorbidity; Female; Fluphenazin

1999
Age at onset of schizophrenia and neuroleptic dosage.
    Social psychiatry and psychiatric epidemiology, 1999, Volume: 34, Issue:12

    Topics: Adult; Age of Onset; Antipsychotic Agents; Clopenthixol; Dose-Response Relationship, Drug; Female; F

1999
Increased incidence of dyskinesias and other behavioral effects of re-exposure to neuroleptic treatment in social colonies of Cebus apella monkeys.
    Psychopharmacology, 2001, Volume: 153, Issue:3

    Topics: Aggression; Animals; Antipsychotic Agents; Cebus; Dyskinesia, Drug-Induced; Female; Fluphenazine; Lo

2001
Lowest effective dose of depot neuroleptics.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 160

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Delayed-Action Preparations; Dose-Response Relationsh

1992
Rationalizing neuroleptic polypharmacy in chronic schizophrenics: effects of changing to a single depot preparation.
    Acta psychiatrica Scandinavica, 1992, Volume: 85, Issue:5

    Topics: Administration, Oral; Antipsychotic Agents; Chronic Disease; Drug Therapy, Combination; Dyskinesia,

1992
Predictors of the course of tardive dyskinesia in patients receiving neuroleptics.
    Biological psychiatry, 1992, Oct-01, Volume: 32, Issue:7

    Topics: Adult; Ambulatory Care; Antipsychotic Agents; Drug Therapy, Combination; Dyskinesia, Drug-Induced; F

1992
Psychotic symptoms preceding ocular deviation in a patient with tardive oculogyric crises.
    The Australian and New Zealand journal of psychiatry, 1992, Volume: 26, Issue:4

    Topics: Adult; Antipsychotic Agents; Benztropine; Chlorpromazine; Dose-Response Relationship, Drug; Dyskines

1992
Life events and schizophrenic relapse after withdrawal of medication.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 161

    Topics: Adaptation, Psychological; Adult; Female; Fluphenazine; Humans; Injections, Intramuscular; Life Chan

1992
Facial dyskinesia: a 16-year follow-up study.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 158

    Topics: Affective Disorders, Psychotic; Aged; Antipsychotic Agents; Brain; Chlorpromazine; Dose-Response Rel

1991
Tardive oculogyric crisis and obsessional thoughts.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 158

    Topics: Dyskinesia, Drug-Induced; Female; Fluphenazine; Humans; Middle Aged; Obsessive-Compulsive Disorder;

1991
Alcohol abuse in chronic schizophrenics: implications for management in the community.
    Acta psychiatrica Scandinavica, 1991, Volume: 84, Issue:3

    Topics: Adult; Alcohol Drinking; Alcoholism; Chronic Disease; Community Mental Health Services; Delayed-Acti

1991
[Clinico-economical aspects of long-term therapy with moditen-depot].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1990, Volume: 90, Issue:12

    Topics: Cost-Benefit Analysis; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Tolerance

1990
An unusual presentation of neuroleptic malignant syndrome.
    Journal of the Indian Medical Association, 1991, Volume: 89, Issue:1

    Topics: Adult; Dose-Response Relationship, Drug; Fluphenazine; Humans; Male; Neuroleptic Malignant Syndrome;

1991
Clinical and toxicological profile of fluphenazine decanoate in elderly chronic schizophrenia.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:4

    Topics: Aged; Basal Ganglia Diseases; Blood Pressure; Electrocardiography; Electroencephalography; Female; F

1990
Noninvasive in vivo detection of a fluorinated neuroleptic in the human brain by 19F nuclear magnetic resonance spectroscopy.
    Psychiatry research, 1990, Volume: 35, Issue:2

    Topics: Adult; Brain Chemistry; Fluorine; Fluphenazine; Humans; Magnetic Resonance Spectroscopy; Male; Schiz

1990
Symptomatic trans-sexualism.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 156

    Topics: Adult; Delayed-Action Preparations; Delusions; Fluphenazine; Humans; Schizophrenia; Schizophrenic Ps

1990
Use of extremely low doses of fluphenazine decanoate.
    The American journal of psychiatry, 1990, Volume: 147, Issue:5

    Topics: Ambulatory Care; Delayed-Action Preparations; Female; Fluphenazine; Humans; Mental Disorders; Middle

1990
Patients' and caregivers' adaptation to improvement in schizophrenia.
    Hospital & community psychiatry, 1990, Volume: 41, Issue:5

    Topics: Adult; Assertiveness; Depressive Disorder; Drug Therapy, Combination; Family; Female; Fluphenazine;

1990
Return of sense of taste with fluphenazine.
    The Journal of neuropsychiatry and clinical neurosciences, 1989,Summer, Volume: 1, Issue:3

    Topics: Brain; Dose-Response Relationship, Drug; Fluphenazine; Humans; Injections, Intramuscular; Neurocogni

1989
Fluphenazine decanoate: a clinical problem?
    The American journal of psychiatry, 1989, Volume: 146, Issue:1

    Topics: Antipsychotic Agents; Chlorpromazine; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; H

1989
Clinical implications of increased antipsychotic plasma concentrations upon anticonvulsant cessation.
    Psychiatry research, 1989, Volume: 28, Issue:2

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Drug Therapy, Combination; Dyskinesia, Drug-Induced; F

1989
Prescribing patterns of neuroactive drugs in 98 schizophrenic patients.
    The Israel journal of psychiatry and related sciences, 1989, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Antipsychotic Agents; Drug Therapy, Combination; Female; Fluphenazine; Humans; Ma

1989
Tardive dyskinesia in outpatients on depot phenothiazine.
    The West Indian medical journal, 1989, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Antipsychotic Agents; Delayed-Action Preparations;

1989
Trials of adjunctive alprazolam in "negative symptom" patients.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1989, Volume: 34, Issue:4

    Topics: Adult; Alprazolam; Depressive Disorder; Drug Therapy, Combination; Fluphenazine; Hallucinations; Hum

1989
Compliance in the long-term treatment of schizophrenia.
    Psychopharmacology bulletin, 1985, Volume: 21, Issue:1

    Topics: Administration, Oral; Antipsychotic Agents; Fluphenazine; Humans; Patient Compliance; Recurrence; Sc

1985
[Intensive psychopharmacologic therapy of slowly-progressive schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1985, Volume: 85, Issue:1

    Topics: Adult; Antipsychotic Agents; Chlordiazepoxide; Diazepam; Female; Fluphenazine; Humans; Infusions, Pa

1985
Selection of neuroleptic dosage.
    Archives of general psychiatry, 1985, Volume: 42, Issue:6

    Topics: Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluphenazine;

1985
Tardive dyskinesia and current dose of neuroleptic drugs.
    Archives of general psychiatry, 1985, Volume: 42, Issue:9

    Topics: Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Flupenthixo

1985
Heatstroke in a chronic schizophrenic patient treated with high-potency neuroleptics.
    General hospital psychiatry, 1985, Volume: 7, Issue:4

    Topics: Antipsychotic Agents; Benztropine; Chronic Disease; Dose-Response Relationship, Drug; Drug Therapy,

1985
Tardive dyskinesia in schizophrenics under 60 years of age.
    Biological psychiatry, 1986, Volume: 21, Issue:2

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, Drug; Dyskinesia, Drug-Ind

1986
[Clinical picture, therapy and rehabilitation of patients with slowly-progressive (psychopath-like) schizophrenia with a loss of work capacity].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:6

    Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Central Ne

1986
[Considerations on the use of long-acting neuroleptics in a mental health center].
    Minerva medica, 1986, Sep-15, Volume: 77, Issue:34-35

    Topics: Adult; Ambulatory Care; Antipsychotic Agents; Delayed-Action Preparations; Depression; Fluphenazine;

1986
[Substitution of fluphenazine decanoate with oxyprothepine decanoate in long-term maintenance therapy in schizophrenia].
    Ceskoslovenska psychiatrie, 1986, Volume: 82, Issue:5

    Topics: Dibenzothiepins; Female; Fluphenazine; Humans; Male; Schizophrenia

1986
Neuroleptic effects on platelet aggregation: a study in normal volunteers and schizophrenics.
    Psychological medicine, 1987, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Delayed-Action Preparations; Flupenthixol;

1987
Clinical symptomatology and drug compliance in schizophrenic patients.
    Acta psychiatrica Scandinavica, 1988, Volume: 77, Issue:1

    Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Female; Flupenthixol; Fluphenazine; Fluspi

1988
Comparative study of the pharmacokinetics of zuclopenthixol decanoate and fluphenazine decanoate.
    Psychopharmacology, 1988, Volume: 94, Issue:3

    Topics: Adult; Antipsychotic Agents; Clopenthixol; Female; Fluphenazine; Humans; Male; Middle Aged; Schizoph

1988
Effects of neuroleptic treatments on peripheral opioid secretion.
    Neuropsychobiology, 1987, Volume: 18, Issue:2

    Topics: Adult; Antipsychotic Agents; beta-Endorphin; beta-Lipotropin; Chlorpromazine; Chronic Disease; Diben

1987
Relapse rate and low serum neuroleptic levels in schizophrenics treated with fluphenazine: another view.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:6

    Topics: Adult; Antipsychotic Agents; Female; Fluphenazine; Follow-Up Studies; Humans; Male; Middle Aged; Pat

1988
Fluphenazine decanoate in acute and maintenance therapy of schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 1987, Volume: 11, Issue:5

    Topics: Acute Disease; Adult; Female; Fluphenazine; Humans; Long-Term Care; Male; Middle Aged; Psychiatric S

1987
The sulfoxidation of fluphenazine in schizophrenic patients maintained on fluphenazine decanoate.
    Psychopharmacology, 1987, Volume: 93, Issue:3

    Topics: Fluphenazine; Gas Chromatography-Mass Spectrometry; Humans; Male; Radioimmunoassay; Schizophrenia

1987
[Results of long-term treatment with depot neuroleptics in schizophrenic patients].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1988, Volume: 40, Issue:3

    Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Fluphenazine; Humans; Long-Term Care

1988
Plasma levels of fluphenazine and prolactin in psychiatric patients.
    European archives of psychiatry and neurological sciences, 1988, Volume: 237, Issue:6

    Topics: Adult; Female; Fluphenazine; Humans; Male; Middle Aged; Personality Disorders; Prolactin; Schizophre

1988
Continuation and maintenance treatment trials of adjunctive imipramine therapy in patients with postpsychotic depression.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:11

    Topics: Benztropine; Depressive Disorder; Drug Therapy, Combination; Fluphenazine; Humans; Imipramine; Psych

1988
Plasma levels of fluphenazine decanoate. Effects of site of injection, massage and muscle activity.
    The British journal of psychiatry : the journal of mental science, 1988, Volume: 153

    Topics: Adolescent; Adult; Chronic Disease; Delayed-Action Preparations; Fluphenazine; Humans; Injections, I

1988
Patterns of plasma imipramine-desipramine concentrations in patients receiving concomitant fluphenazine decanoate.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:2

    Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug T

1988
Changing from oral to depot fluphenazine.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:9

    Topics: Administration, Oral; Body Weight; Drug Administration Schedule; Fluphenazine; Humans; Schizophrenia

1988
Depot neuroleptic medication and serum levels by radioreceptor assay: prolactin concentration, electrocardiogram abnormalities and six-month outcome.
    The Australian and New Zealand journal of psychiatry, 1987, Volume: 21, Issue:3

    Topics: Adult; Delayed-Action Preparations; Dose-Response Relationship, Drug; Electrocardiography; Female; F

1987
L-5-Hydroxytryptophan-induced delirium.
    Biological psychiatry, 1986, Volume: 21, Issue:7

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Delirium; Double-Blind Method; Drug Therapy, Combi

1986
Family psychoeducation, social skills training, and medication in schizophrenia: the long and short of it.
    Psychopharmacology bulletin, 1987, Volume: 23, Issue:1

    Topics: Behavior Therapy; Combined Modality Therapy; Family Therapy; Fluphenazine; Humans; Schizophrenia

1987
Invitation to compliance. The Prolixin brunch.
    Journal of psychosocial nursing and mental health services, 1987, Volume: 25, Issue:10

    Topics: Adult; Delayed-Action Preparations; Female; Fluphenazine; Humans; Male; Middle Aged; Patient Complia

1987
Plasma prolactin and fluphenazine concentrations in patients receiving fluphenazine decanoate: stability over injection intervals.
    International clinical psychopharmacology, 1987, Volume: 2, Issue:4

    Topics: Adult; Female; Fluphenazine; Humans; Male; Middle Aged; Prolactin; Schizophrenia

1987
Relapse in chronic schizophrenics treated with fluphenazine decanoate is associated with low serum neuroleptic levels.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:5

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Chronic Disease; Female; Fluphenazine; Humans; Injections,

1986
Is postpsychotic depression a primary affective disorder?
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:9

    Topics: Depressive Disorder; Fluphenazine; Humans; Psychotic Disorders; Schizophrenia

1986
Expressed emotion, fixed-dose fluphenazine decanoate maintenance, and relapse in recent-onset schizophrenia.
    Psychopharmacology bulletin, 1986, Volume: 22, Issue:3

    Topics: Adult; Emotions; Family; Female; Fluphenazine; Humans; Male; Recurrence; Schizophrenia; Schizophreni

1986
Flupenthixol decanoate and fluphenazine decanoate in chronic schizophrenia.
    Singapore medical journal, 1985, Volume: 26, Issue:7

    Topics: Adult; Chronic Disease; Female; Flupenthixol; Fluphenazine; Humans; Male; Middle Aged; Schizophrenia

1985
Plasma levels of fluphenazine during fluphenazine decanoate treatment in schizophrenia.
    Psychopharmacology, 1985, Volume: 87, Issue:1

    Topics: Adolescent; Adult; Chromatography, Gas; Female; Fluphenazine; Humans; Male; Schizophrenia

1985
[Depressive syndromes within the scope of schizophrenic psychoses].
    Wiener medizinische Wochenschrift (1946), 1985, Sep-30, Volume: 135, Issue:18

    Topics: Depressive Disorder; Fluphenazine; Hallucinations; Humans; Long-Term Care; Male; Models, Psychologic

1985
Stability of the postpsychotic depression syndrome.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:2

    Topics: Adult; Depressive Disorder; Female; Fluphenazine; Humans; Male; Middle Aged; Outcome and Process Ass

1986
Serum neuroleptic levels and clinical outcome in schizophrenic patients treated with fluphenazine decanoate.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:3

    Topics: Adult; Aged; Chronic Disease; Dose-Response Relationship, Drug; Female; Fluphenazine; Humans; Male;

1985
Long-acting therapy of schizophrenia.
    Advances in biochemical psychopharmacology, 1985, Volume: 40

    Topics: Adolescent; Adult; Antiparkinson Agents; Benzodiazepines; Biofeedback, Psychology; Bromocriptine; Dy

1985
Plasma levels of neuroleptic in patients receiving depot fluphenazine.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:6

    Topics: Delayed-Action Preparations; Fluphenazine; Humans; Regression Analysis; Schizophrenia

1985
Depot fluphenazine and plasma prolactin.
    Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:4

    Topics: Drug Tolerance; Female; Fluphenazine; Humans; Male; Prolactin; Schizophrenia; Sex Factors

1985