fluphenazine depot has been researched along with Neuroleptic Malignant Syndrome in 10 studies
fluphenazine decanoate : The prodrug of fluphenazine, an antipsychotic drug used for the symptomatic management of psychosis in patients with schizophrenia.
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A mild form of neuroleptic malignant syndrome (NMS) in a schizophrenic patient who was receiving a depot neuroleptic is described and beneficial response to oral diazepam 50 mg daily is reported." | 7.67 | Treatment of a mild form of neuroleptic malignant syndrome with oral diazepam. ( Christodoulou, GN; Havaki-Kontaxaki, BJ; Kontaxakis, VP; Markidis, MP, 1988) |
| "A mild form of neuroleptic malignant syndrome (NMS) in a schizophrenic patient who was receiving a depot neuroleptic is described and beneficial response to oral diazepam 50 mg daily is reported." | 3.67 | Treatment of a mild form of neuroleptic malignant syndrome with oral diazepam. ( Christodoulou, GN; Havaki-Kontaxaki, BJ; Kontaxakis, VP; Markidis, MP, 1988) |
| "The estimated prevalence of neuroleptic malignant syndrome in these psychiatric inpatients was 1." | 1.28 | Neuroleptic malignant syndrome in 12 of 9,792 Chinese inpatients exposed to neuroleptics: a prospective study. ( Chen, GQ; Deng, MZ; Phillips, MR, 1990) |
| "The neuroleptic malignant syndrome is an exceedingly rare but potentially fatal condition characterized by parkinsonian type rigidity, rise of temperature and altered consciousness." | 1.28 | An unusual presentation of neuroleptic malignant syndrome. ( Basu, J, 1991) |
| "In a fatal case of neuroleptic malignant syndrome, a muscle sample taken within 1 h of death showed acute myopathic features with absence of muscle glycogen and neutral lipid." | 1.27 | Muscle pathology in the neuroleptic malignant syndrome. ( Martin, DT; Swash, M, 1987) |
| "The neuroleptic malignant syndrome is an uncommon but occasionally fatal reaction to antipsychotic medication characterized by fever, movement disorder, and stupor." | 1.27 | A case of neuroleptic malignant syndrome in a mentally retarded adolescent. ( Diamond, JM; Hayes, DD, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cape, G | 1 |
| Spivak, B | 1 |
| Gonen, N | 1 |
| Mester, R | 1 |
| Averbuch, E | 1 |
| Adlersberg, S | 1 |
| Weizman, A | 1 |
| Deng, MZ | 1 |
| Chen, GQ | 1 |
| Phillips, MR | 1 |
| Basu, J | 1 |
| Krystal, AD | 1 |
| McEvoy, JP | 1 |
| Pope, HG | 1 |
| Cole, JO | 1 |
| Choras, PT | 1 |
| Fulwiler, CE | 1 |
| Kontaxakis, VP | 1 |
| Christodoulou, GN | 1 |
| Markidis, MP | 1 |
| Havaki-Kontaxaki, BJ | 1 |
| Martin, DT | 1 |
| Swash, M | 1 |
| Diamond, JM | 1 |
| Hayes, DD | 1 |
| Blue, MG | 1 |
| Schneider, SM | 1 |
| Noro, S | 1 |
| Fraley, DS | 1 |
10 other studies available for fluphenazine depot and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Neuroleptic malignant syndrome--a cautionary tale and a surprising outcome.
Topics: Activities of Daily Living; Adaptation, Psychological; Adult; Antisocial Personality Disorder; Combi | 1994 |
Neuroleptic malignant syndrome associated with abrupt withdrawal of anticholinergic agents.
Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Fluphenazine; Humans; Male; Muscarinic Ant | 1996 |
Neuroleptic malignant syndrome in 12 of 9,792 Chinese inpatients exposed to neuroleptics: a prospective study.
Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; China; Confidence Intervals; Delayed-Action Prepa | 1990 |
An unusual presentation of neuroleptic malignant syndrome.
Topics: Adult; Dose-Response Relationship, Drug; Fluphenazine; Humans; Male; Neuroleptic Malignant Syndrome; | 1991 |
Shared features of neuroleptic malignant syndrome and alcohol abuse complications.
Topics: Adult; Diagnosis, Differential; Ethanol; Fluphenazine; Humans; Male; Neuroleptic Malignant Syndrome; | 1990 |
Apparent neuroleptic malignant syndrome with clozapine and lithium.
Topics: Adult; Bipolar Disorder; Clozapine; Dibenzazepines; Drug Therapy, Combination; Fluphenazine; Humans; | 1986 |
Treatment of a mild form of neuroleptic malignant syndrome with oral diazepam.
Topics: Administration, Oral; Adult; Diazepam; Drug Therapy, Combination; Fluphenazine; Humans; Injections, | 1988 |
Muscle pathology in the neuroleptic malignant syndrome.
Topics: Adult; Fluphenazine; Humans; Male; Muscles; Neuroleptic Malignant Syndrome; Procyclidine; Psychotic | 1987 |
A case of neuroleptic malignant syndrome in a mentally retarded adolescent.
Topics: Adolescent; Aggression; Fluphenazine; Humans; Intellectual Disability; Male; Neuroleptic Malignant S | 1986 |
Successful treatment of neuroleptic malignant syndrome with sodium nitroprusside.
Topics: Combined Modality Therapy; Female; Ferricyanides; Fluphenazine; Humans; Loxapine; Middle Aged; Neuro | 1986 |