fluphenazine has been researched along with Tourette Syndrome in 11 studies
Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluphenazine appears to be safe and effective in the treatment of TS, and there were no cases of TD in this cohort treated up to 16." | 5.40 | Long-term efficacy and safety of fluphenazine in patients with Tourette syndrome. ( Jankovic, J; Wijemanne, S; Wu, LJ, 2014) |
| "The neurological disorder Gilles de la Tourette syndrome is most often treated with the receptor blocker haloperidol, which also produces multiple side-effects, including the risk for tardive dyskinesia." | 5.05 | Treatment approaches in Gilles de la Tourette syndrome. ( Ang, L; Borison, RL; Davis, JM; Diamond, BI; Hamilton, WJ, 1983) |
| "Fluphenazine appears to be safe and effective in the treatment of TS, and there were no cases of TD in this cohort treated up to 16." | 1.40 | Long-term efficacy and safety of fluphenazine in patients with Tourette syndrome. ( Jankovic, J; Wijemanne, S; Wu, LJ, 2014) |
| "Since both tardive dyskinesia and Tourette's disease are thought to be caused by relative overactivity or supersensitivity of the dopamine system, their reversible appearance after long term dopamine receptor blockade by neuroleptics can be expected in susceptible individuals." | 1.26 | Tardive dyskinesia with Tourette-like syndrome. ( Patel, J; Pyke, J; Seeman, MV, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wijemanne, S | 1 |
| Wu, LJ | 1 |
| Jankovic, J | 1 |
| Klawans, HL | 3 |
| Nausieda, PA | 1 |
| Goetz, CC | 1 |
| Tanner, CM | 3 |
| Weiner, WJ | 1 |
| Shapiro, AK | 1 |
| Shapiro, E | 1 |
| Eisenkraft, GJ | 1 |
| Borison, RL | 2 |
| Ang, L | 2 |
| Hamilton, WJ | 1 |
| Diamond, BI | 1 |
| Davis, JM | 2 |
| Goetz, CG | 2 |
| Chang, S | 1 |
| Dysken, M | 1 |
| Comaty, JE | 1 |
| Seeman, MV | 1 |
| Patel, J | 1 |
| Pyke, J | 1 |
| Buitelaar, JK | 1 |
| Erenberg, G | 1 |
| Cruse, RP | 1 |
| Rothner, AD | 1 |
1 review available for fluphenazine and Tourette Syndrome
| Article | Year |
|---|---|
Self-injurious behaviour in retarded children: clinical phenomena and biological mechanisms.
Topics: Antipsychotic Agents; Brain; Dopamine; Female; Fluphenazine; Humans; Intellectual Disability; Lesch- | 1993 |
4 trials available for fluphenazine and Tourette Syndrome
| Article | Year |
|---|---|
Treatment of Gilles de la Tourette's syndrome with clonidine and neuroleptics.
Topics: Adult; Antipsychotic Agents; Attitude to Health; Clinical Trials as Topic; Clonidine; Drug Therapy, | 1983 |
Treatment approaches in Gilles de la Tourette syndrome.
Topics: Amantadine; Benztropine; Clonidine; Fluphenazine; Haloperidol; Humans; Lithium; Tourette Syndrome; T | 1983 |
New pharmacological approaches in the treatment of Tourette syndrome.
Topics: Adolescent; Adult; Amantadine; Benztropine; Child; Clinical Trials as Topic; Clonidine; Female; Flup | 1982 |
Haloperidol in psychiatry.
Topics: Anxiety Disorders; Basal Ganglia Diseases; Clinical Trials as Topic; Dopamine Antagonists; Fluphenaz | 1975 |
6 other studies available for fluphenazine and Tourette Syndrome
| Article | Year |
|---|---|
Long-term efficacy and safety of fluphenazine in patients with Tourette syndrome.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dopamine Antagonists; Female; Fluphenazine; Humans | 2014 |
Tourette-like symptoms following chronic neuroleptic therapy.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Female; Fluphenazine; Haloperidol; Humans; Time F | 1982 |
Fluphenazine and multifocal tic disorders.
Topics: Adolescent; Adult; Child; Female; Fluphenazine; Humans; Male; Middle Aged; Tic Disorders; Tourette S | 1984 |
Tardive dyskinesia with Tourette-like syndrome.
Topics: Adult; Delayed-Action Preparations; Dyskinesia, Drug-Induced; Female; Fluphenazine; Humans; Receptor | 1981 |
Compressive neuropathies in Tourette syndrome.
Topics: Adolescent; Adult; Female; Fluphenazine; Haloperidol; Humans; Male; Nerve Compression Syndromes; Tou | 1982 |
The natural history of Tourette syndrome: a follow-up study.
Topics: Adaptation, Psychological; Adolescent; Adolescent Behavior; Adult; Aging; Clonidine; Fluphenazine; F | 1987 |