Compounds > fluphenazine
Page last updated: 2024-10-27

fluphenazine and Pregnancy

fluphenazine has been researched along with Pregnancy in 33 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" The pregnancy was complicated by chronic maternal schizophrenia, severe toxaemia and maternal use of fluphenazine enanthate, dicyclomine hydrochloride, doxylamine succinate, pyridoxine hydrochloride and other drugs."7.66Multiple congenital abnormalities in a newborn boy associated with maternal use of fluphenazine enanthate and other drugs during pregnancy. ( Bury, RG; Donaldson, GL, 1982)
" This study will present our own experience in the treatment of a pregnant woman suffering from schizophrenia, who was treated with ziprasidone for the duration of her pregnancy."3.75Pregnancy and atypical antipsychotics. ( Dadić-Hero, E; Knez, R; Medved, P; Petrić, D; Ruzić, K, 2009)
" We describe a newborn who had severe rhinorrhea, vomiting, and respiratory distress after being exposed in utero to fluphenazine hydrochloride."3.69Severe rhinorrhea and respiratory distress in a neonate exposed to fluphenazine hydrochloride prenatally. ( Miller, DA; Muraskas, JK; Nath, SP, 1996)
" The pregnancy was complicated by chronic maternal schizophrenia, severe toxaemia and maternal use of fluphenazine enanthate, dicyclomine hydrochloride, doxylamine succinate, pyridoxine hydrochloride and other drugs."3.66Multiple congenital abnormalities in a newborn boy associated with maternal use of fluphenazine enanthate and other drugs during pregnancy. ( Bury, RG; Donaldson, GL, 1982)
"Hyperprolactinemia is a known side-effect of fluphenazine, a broad spectrum, long-acting phenothiazine known to be D2 dopamine receptor antagonist."1.32Antifertility effects of fluphenazine in adult male rats. ( Aleem, M; Balasinor, N; Choudhary, J; D'Souza, S; Gill-Sharma, MK; Juneja, HS; Padwal, V; Parte, P; Sethi, G, 2003)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199027 (81.82)18.7374
1990's3 (9.09)18.2507
2000's3 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ruzić, K1
Dadić-Hero, E1
Knez, R1
Medved, P1
Petrić, D1
Gill-Sharma, MK1
Aleem, M1
Sethi, G1
Choudhary, J1
Padwal, V1
D'Souza, S1
Balasinor, N1
Parte, P1
Juneja, HS1
MCQUEEN, EG1
PRICE, JJ1
BARRY, MC1
DE FREITAS, EZ2
BISLEY, BL1
KAY, CR1
Terry, PM1
Sapag-Hagar, M2
Puente, J2
Muñoz, A2
Piedad Valdivieso, M1
Diaz, S1
Donoso, E2
Pizarro, M1
Coulter, DM1
Donaldson, GL1
Bury, RG1
O'Connor, M1
Johnson, GH1
James, DI1
Merlob, P1
Stahl, B1
Maltz, E1
Nath, SP1
Miller, DA1
Muraskas, JK1
Robinson, D1
Woerner, MG1
Alvir, JM1
Bilder, R1
Goldman, R1
Geisler, S1
Koreen, A1
Sheitman, B1
Chakos, M1
Mayerhoff, D1
Lieberman, JA1
Ryan, PL1
Bennett-Wimbush, K1
Vaala, WE1
Bagnell, CA1
Rise, A1
Lanza, JP1
Goude, F1
Lanza, M1
Cleary, MF1
Trzeciak, HI1
Herman, ZS1
Szkilnik, R1
Banik, UK1
Givner, ML1
Shanker, G1
Pieringer, RA1
Lavandero, S1
Lorber, CG1
Kelsey, MI1
Keskiner, A1
Moscatelli, EA1
Mishkinsky, J1
Khazen, K1
Sulman, FG1
Jones, GL1
Ravel, R1
Riekers, HG1
Goldstein, BJ1
Blobel, R2
Bidlingmaier, R1
Ayd, FJ1
Najar Origel, S1
Louro, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
ExPRESS:2 (Experiences of Psychosis Relapse: Early Subjective Signs) Longitudinal Feasibility Study[NCT03558529]27 participants (Actual)Observational2015-05-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

33 other studies available for fluphenazine and Pregnancy

ArticleYear
Pregnancy and atypical antipsychotics.
    Psychiatria Danubina, 2009, Volume: 21, Issue:3

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Drug Therapy, Combination; Female; Fluphenazine; Human

2009
Antifertility effects of fluphenazine in adult male rats.
    Journal of endocrinological investigation, 2003, Volume: 26, Issue:4

    Topics: Animals; Disease Models, Animal; Dopamine Antagonists; Embryo Implantation; Female; Fertility; Fluph

2003
TOXIC EFFECTS OF PHENOTHIAZINE TRANQUILLIZERS.
    The New Zealand medical journal, 1963, Volume: 62

    Topics: Central Nervous System Diseases; Chlorpromazine; Epilepsy; Female; Fluphenazine; Hypotension; Jaundi

1963
A DOUBLE BLIND STUDY OF FLUPHENAZINE WITH PYRIDOXINE.
    Pennsylvania medical journal (1928), 1964, Volume: 67

    Topics: Biometry; Double-Blind Method; Female; Fluphenazine; Humans; Hyperemesis Gravidarum; Placebos; Pregn

1964
[USE OF FLUPHENAZINE HYDROCHLORIDE IN NAUSEA AND VOMITING IN PREGNANCY].
    Revista de ginecologia e d'obstetricia, 1964, Volume: 114

    Topics: Female; Fluphenazine; Humans; Hyperemesis Gravidarum; Nausea; Pregnancy; Pregnancy Complications; Vo

1964
[USE OF FLUPHENAZINE HYDROCHLORIDE IN NERVOUS TENSION IN THE PREPARTAL PERIOD].
    Revista de ginecologia e d'obstetricia, 1964, Volume: 114

    Topics: Anxiety; Anxiety Disorders; Female; Fluphenazine; Humans; Mental Disorders; Pregnancy; Pregnancy Com

1964
ANTI-EMETIC EFFECTS OF A PHENOTHIAZINE COMPARED WITH AN ANTIHISTAMINE.
    The Practitioner, 1964, Volume: 193

    Topics: Anti-Allergic Agents; Antiemetics; Biomedical Research; Chlorpheniramine; Family Practice; Female; F

1964
Side-effects of phenothiazines.
    British medical journal, 1967, Apr-01, Volume: 2, Issue:5543

    Topics: Adult; Female; Fluphenazine; Humans; Male; Movement Disorders; Perphenazine; Pregnancy; Trifluoperaz

1967
[Hormonal action and second messengers in lactogenesis].
    Revista medica de Chile, 1984, Volume: 112, Issue:2

    Topics: Adenylyl Cyclases; Animals; Breast; Calmodulin; Cyclic AMP; Cyclic GMP; Female; Fluphenazine; Lactat

1984
Differing effects of prolactin on the water content of individual tissues in the rabbit pup at 72 h of age.
    Biology of the neonate, 1984, Volume: 46, Issue:3

    Topics: Animals; Animals, Newborn; Body Water; Body Weight; Brain; Female; Fluphenazine; Liver; Muscles; Pre

1984
Multiple congenital abnormalities in a newborn boy associated with maternal use of fluphenazine enanthate and other drugs during pregnancy.
    Acta paediatrica Scandinavica, 1982, Volume: 71, Issue:2

    Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Female; Fluphenazine;

1982
Intrauterine effect of phenothiazines.
    The Medical journal of Australia, 1981, Apr-18, Volume: 1, Issue:8

    Topics: Adult; Chlorpromazine; Dystonia; Female; Fluphenazine; Humans; Infant; Infant, Newborn; Infant, Newb

1981
Is fluphenazine a teratogen?
    American journal of medical genetics, 1994, Aug-15, Volume: 52, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Animals; Chick Embryo; Female; Fluphena

1994
Severe rhinorrhea and respiratory distress in a neonate exposed to fluphenazine hydrochloride prenatally.
    The Annals of pharmacotherapy, 1996, Volume: 30, Issue:1

    Topics: Antipsychotic Agents; Female; Fluphenazine; Humans; Infant, Newborn; Mucus; Nasal Mucosa; Pregnancy;

1996
Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder.
    Archives of general psychiatry, 1999, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Antipsychotic Agents; Cohort Studies; Female; Fluphenazine; Follow-Up Studies; Ha

1999
Systemic relaxin in pregnant pony mares grazed on endophyte-infected fescue: effects of fluphenazine treatment.
    Theriogenology, 2001, Aug-01, Volume: 56, Issue:3

    Topics: Acremonium; Animals; Dopamine Antagonists; Ergotism; Female; Fluphenazine; Horse Diseases; Horses; P

2001
[Neuroleptics].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Mar-10, Volume: 96, Issue:7

    Topics: Abnormalities, Drug-Induced; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Female; Fluphenaz

1976
[Effect of a single dose of some long-acting neuroleptics on the estrus cycle and the mammary gland of the rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1979, Volume: 173, Issue:4

    Topics: Animals; Antipsychotic Agents; Caproates; Estrus; Female; Flupenthixol; Fluphenazine; Mammary Glands

1979
Fluphenazine decanoate during pregnancy.
    The American journal of psychiatry, 1977, Volume: 134, Issue:7

    Topics: Adult; Delayed-Action Preparations; Female; Fluphenazine; Humans; Pregnancy; Pregnancy Complications

1977
Behavioral effects of withdrawal of fluphenazine after long-term treatment.
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:9

    Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Drug Tolerance; Female; Fluphenazine; Huma

1976
Ovulation induction and antifertility effects of an LH-RH analogue (AY 25,205) in cyclic rats.
    Journal of reproduction and fertility, 1975, Volume: 44, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Estrus; Female; Fertility; Fluphenazine; Gonadotropin-Rel

1975
Developmental study on the regulation of neurotransmitter-sensitive adenylate cyclase systems in primary cerebral cell cultures from embryonic mice.
    Bioscience reports, 1985, Volume: 5, Issue:7

    Topics: Adenylyl Cyclases; Animals; Brain; Cells, Cultured; Dopamine; Epinephrine; Female; Fluphenazine; Iso

1985
A role for adrenaline and calmodulin in modulating cyclic AMP levels during the lactogenic cycle.
    FEBS letters, 1985, Jul-22, Volume: 187, Issue:1

    Topics: Animals; Calmodulin; Colforsin; Cyclic AMP; Diterpenes; Epinephrine; Female; Fluphenazine; Lactation

1985
[Anti-inflammatory agents in dentistry].
    ZWR, 1974, Sep-10, Volume: 83, Issue:17

    Topics: Adult; Anti-Inflammatory Agents; Chymotrypsin; Edema; Female; Fluphenazine; Humans; Indomethacin; In

1974
Gas-liquid chromatographic analysis of fluphenazine and fluphenazine sulfoxide in the urine of chronic schizophrenic patients.
    Journal of chromatography, 1973, Jan-17, Volume: 75, Issue:2

    Topics: Animals; Chromatography, Gas; Chronic Disease; Estrus; Female; Fluphenazine; Humans; Methods; Pregna

1973
Mammotropic effect of fluphenazine enanthate in the rat.
    Neuroendocrinology, 1969, Volume: 4, Issue:6

    Topics: Animals; Cacao; Chemical Phenomena; Chemistry; Estradiol; Female; Fluphenazine; Hypothalamus; Inject

1969
Abnormal lactation associated with fluphenazine enanthate.
    The Journal of the Medical Society of New Jersey, 1968, Volume: 65, Issue:5

    Topics: Adult; Female; Fluphenazine; Humans; Lactation Disorders; Mental Disorders; Pregnancy

1968
Effects of certain psychotropic drugs on immunologic pregnancy tests.
    American journal of obstetrics and gynecology, 1969, Dec-15, Volume: 105, Issue:8

    Topics: Chlorpromazine; Chlorprothixene; Chorionic Gonadotropin; False Positive Reactions; Female; Fluphenaz

1969
[Regulation of experimentally induced cycleic disorders in rats by a neuroleptic].
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:7

    Topics: Animals; Estrus; Female; Fluphenazine; Light; Menstruation; Menstruation Disturbances; Noise; Pregna

1967
Fluphenazine: twelve years' experience.
    Diseases of the nervous system, 1968, Volume: 29, Issue:11

    Topics: Female; Fluphenazine; Humans; Mental Disorders; Movement Disorders; Pregnancy; Schizophrenia

1968
[Hyperemesis gravidarum as an obstetrical problem. Its treatment with fluphenazine and pyridoxine].
    Medicina, 1965, Oct-10, Volume: 45, Issue:973

    Topics: Adult; Female; Fluphenazine; Humans; Hyperemesis Gravidarum; Pregnancy; Pyridoxine

1965
[Management of the first stage of labor. (Use of combined fluphenazine and meperidine)].
    Revista de ginecologia e d'obstetricia, 1965, Volume: 116, Issue:5

    Topics: Anesthesia, Obstetrical; Anxiety; Female; Fluphenazine; Humans; Meperidine; Obstetric Labor Complica

1965
[Control of induced estrus cycle disorders in rats by fluphenazine].
    Geburtshilfe und Frauenheilkunde, 1966, Volume: 26, Issue:5

    Topics: Animals; Estrus; Female; Fluphenazine; Periodicity; Pregnancy; Rats

1966