fluphenazine has been researched along with Parkinson Disease, Secondary in 44 studies
Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A trial involving patients receiving fluphenazine decanoate was designed to compare the effects of orphenadrine hydrochloride (Disipal) and its major metabolite, tofenacin hydrochloride (Elamol) on the Parkinsonian side-effects and depression occurring during fluphenazine decanoate therapy." | 9.04 | A comparative trial of orphenadrine and tofenacin in the control of depression and extrapyramidal side-effects associated with fluphenazine decanoate therapy. ( Capstick, N; Pudney, H, 1976) |
| "/day) versus fixed standard dosage (20 mg." | 6.64 | High vs standard dosage fluphenazine HCL in acute schizophrenia. ( Donlon, PT; Meadow, A; Tupin, JP; Wahba, M, 1978) |
| "A double-blind, cross-over trial of the effectiveness of piribedil, procyclidine and placebo in the control of parkinsonism induced by fluphenazine decanoate was conducted in sixteen cases of chronic schizophrenia." | 5.04 | A comparison of piribedil, procyclidine and placebo in the control of phenothiazine-induced parkinsonism. ( Bradley, R; Lamb, P; Mindham, RH, 1977) |
| "A trial involving patients receiving fluphenazine decanoate was designed to compare the effects of orphenadrine hydrochloride (Disipal) and its major metabolite, tofenacin hydrochloride (Elamol) on the Parkinsonian side-effects and depression occurring during fluphenazine decanoate therapy." | 5.04 | A comparative trial of orphenadrine and tofenacin in the control of depression and extrapyramidal side-effects associated with fluphenazine decanoate therapy. ( Capstick, N; Pudney, H, 1976) |
| "During long-term treatment of schizophrenia with antipsychotic medication, side effects such as weight gain and tardive dyskinesia may develop, while other extrapyramidal side effects may continue." | 2.67 | Side effects during long-term treatment with depot antipsychotic medication. ( Cookson, JC, 1991) |
| " Improvement was recorded in a double blind study of 18 patients treated with maximum tolerated dosage (mean 18." | 2.64 | Tardive dyskinesia treated with pimozide. ( Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF, 1975) |
| "/day) versus fixed standard dosage (20 mg." | 2.64 | High vs standard dosage fluphenazine HCL in acute schizophrenia. ( Donlon, PT; Meadow, A; Tupin, JP; Wahba, M, 1978) |
| "We report the singular case of a 31-year-old woman who developed very serious Fluphenazine-induced parkinsonism over a few days due to a doubly incongruent drug prescription by indication and dosage having been applied to a healthy subject over one week instead of seven months." | 1.91 | Fluphenazine-Induced Neurotoxicity with Acute Almost Transient Parkinsonism and Permanent Memory Loss: Lessons from a Case Report. ( Costa, MC; De Masi, R; Orlando, S; Toni, V, 2023) |
| "A patient with schizoaffective disorder and anticholinergic refractory neuroleptic-induced parkinsonism manifested a marked increase of parkinsonian symptoms and dystonia after ECT." | 1.29 | An unusual effect of ECT on drug-induced parkinsonism and tardive dystonia. ( Hanin, B; Lerner, Y; Srour, N, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (88.64) | 18.7374 |
| 1990's | 4 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.27) | 2.80 |
| Authors | Studies |
|---|---|
| De Masi, R | 1 |
| Orlando, S | 1 |
| Toni, V | 1 |
| Costa, MC | 1 |
| Sheppard, C | 1 |
| Merlis, S | 1 |
| Barnes, TR | 2 |
| Wiles, DH | 1 |
| Hanin, B | 1 |
| Lerner, Y | 1 |
| Srour, N | 1 |
| Dhopesh, V | 1 |
| Macfadden, A | 1 |
| Maany, I | 1 |
| Gamble, G | 1 |
| Mindham, RH | 4 |
| Small, JG | 1 |
| Kellams, JJ | 1 |
| Milstein, V | 1 |
| Klapper, M | 1 |
| Lemberger, L | 1 |
| Chouinard, G | 2 |
| Annable, L | 2 |
| Ross-Chouinard, A | 2 |
| Nestoros, JN | 1 |
| Kropsky, ML | 1 |
| Lamb, P | 2 |
| Ezzat, MA | 1 |
| Claveria, LE | 1 |
| Teychenne, PF | 1 |
| Calne, DB | 1 |
| Haskayne, L | 1 |
| Petrie, A | 1 |
| Pallis, CA | 1 |
| Lodge-Patch, IC | 1 |
| Martin, IC | 1 |
| Bradley, R | 1 |
| Frangos, H | 1 |
| Zissis, NP | 1 |
| Leontopoulos, I | 1 |
| Diamantas, N | 1 |
| Tsitouridis, S | 1 |
| Gavriil, I | 1 |
| Tsolis, K | 1 |
| Donlon, PT | 1 |
| Meadow, A | 1 |
| Tupin, JP | 1 |
| Wahba, M | 1 |
| Jose, C | 1 |
| Mallya, A | 1 |
| Mehta, D | 1 |
| Evenson, R | 1 |
| Holland, R | 1 |
| Raskind, M | 1 |
| Alvarez, C | 1 |
| Herlin, S | 1 |
| Capstick, N | 1 |
| Pudney, H | 1 |
| De Fraites, EG | 1 |
| Davis, KL | 1 |
| Berger, PA | 1 |
| Gelenberg, AJ | 1 |
| Mandel, MR | 1 |
| Schulz, HD | 1 |
| Kluge, HH | 1 |
| Korda, W | 1 |
| Kube, B | 1 |
| Cookson, JC | 1 |
| Brewer, BD | 1 |
| Hines, MT | 1 |
| Stewart, JT | 1 |
| Langlois, JF | 1 |
| Hirschberg, E | 1 |
| Curson, DA | 1 |
| Bamber, RW | 1 |
| Platt, SD | 1 |
| Hirsch, SR | 1 |
| Duffy, JC | 1 |
| Escande, M | 1 |
| Vasquez Villareal, S | 1 |
| Gayral, L | 1 |
| Whittier, JR | 1 |
| Korenyi, C | 1 |
| Boelkins, RC | 1 |
| Bordeleau, JM | 1 |
| Tétreault, L | 1 |
| Davidson, J | 1 |
| Gaind, R | 1 |
| Anstee, BH | 1 |
| Rimmer, L | 1 |
| Ayd, FJ | 1 |
| Itil, TM | 1 |
| Patterson, CD | 1 |
| Keskiner, A | 1 |
| Holden, JM | 1 |
| Angst, J | 1 |
| Frei, M | 1 |
| Dreyfuss, J | 1 |
| Beer, B | 1 |
| Devine, DD | 1 |
| Roberts, BF | 1 |
| Schreiber, EC | 1 |
| Schwingenheuer, J | 1 |
| Johnson, DA | 1 |
| Engstrand, E | 1 |
| Morris, PA | 1 |
| MacKenzie, DH | 1 |
| Masheter, HC | 1 |
| Haddenbrock, S | 1 |
| Náhunek, K | 1 |
| Rodová, A | 1 |
| Svestka, J | 1 |
| Simpson, GM | 1 |
| Kurland, AA | 1 |
| Dim, BH | 1 |
| Olsson, JE | 1 |
| West, D | 1 |
1 review available for fluphenazine and Parkinson Disease, Secondary
| Article | Year |
|---|---|
Side effects of depot fluphenazines.
Topics: Agranulocytosis; Barbiturates; Basal Ganglia Diseases; Benztropine; Biperiden; Delayed-Action Prepar | 1974 |
16 trials available for fluphenazine and Parkinson Disease, Secondary
| Article | Year |
|---|---|
Assessment of drugs in schizophrenia. Asessment of drug-induced extrapyramidal reactions and of drugs given for their control.
Topics: Amantadine; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Clinical Trials as T | 1976 |
Effects of lergotrile on schizophrenia & drug induced parkinsonism.
Topics: Acetonitriles; Adult; Antiparkinson Agents; Antipsychotic Agents; Chronic Disease; Clinical Trials a | 1977 |
Ethopropazine and benztropine in neuroleptic-induced parkinsonism.
Topics: Adult; Benztropine; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; Female; | 1979 |
Tardive dyskinesia treated with pimozide.
Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousnes | 1975 |
Implications of phenothiazine side effects: a study of antiparkinsonian agents in an older population.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Delayed-Action Preparat | 1975 |
A comparison of piribedil, procyclidine and placebo in the control of phenothiazine-induced parkinsonism.
Topics: Chronic Disease; Clinical Trials as Topic; Fluphenazine; Humans; Parkinson Disease; Parkinson Diseas | 1977 |
Double-blind therapeutic evaluation of fluspirilene compared with fluphenazine decanoate in chronic schizophrenics.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Fluphenazine; Fluspir | 1978 |
High vs standard dosage fluphenazine HCL in acute schizophrenia.
Topics: Acute Disease; Adult; Benztropine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Doubl | 1978 |
A comparative trial of orphenadrine and tofenacin in the control of depression and extrapyramidal side-effects associated with fluphenazine decanoate therapy.
Topics: Clinical Trials as Topic; Depression; Fluphenazine; Humans; Orphenadrine; Parkinson Disease, Seconda | 1976 |
Side effects during long-term treatment with depot antipsychotic medication.
Topics: Akathisia, Drug-Induced; Delayed-Action Preparations; Double-Blind Method; Dyskinesia, Drug-Induced; | 1991 |
Long-term depot maintenance of chronic schizophrenic out-patients: the seven year follow-up of the Medical Research Council fluphenazine/placebo trial. II. The incidence of compliance problems, side-effects, neurotic symptoms and depression.
Topics: Clinical Trials as Topic; Delayed-Action Preparations; Depressive Disorder; Double-Blind Method; Dys | 1985 |
Comparison of amantadine, orphenadrine, and placebo in the control of phenothiazine-induced Parkinsonism.
Topics: Affect; Amantadine; Basal Ganglia Diseases; Clinical Trials as Topic; Evaluation Studies as Topic; F | 1972 |
Comparison of phenothiazine and nonphenothiazine neuroleptics according to psychopathology, side effects and computerized EEG.
Topics: Alpha Rhythm; Chronic Disease; Clinical Trials as Topic; Computers; Electroencephalography; Female; | 1974 |
[The depot neuroleptic agent fluspirilene (author's transl)].
Topics: Basal Ganglia Diseases; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Female; Fluoroben | 1973 |
[Fluphenazine enanthate in long term treatment of psychoses].
Topics: Clinical Trials as Topic; Fluphenazine; Humans; Male; Parkinson Disease, Secondary; Psychotic Disord | 1969 |
A comparative double blind trial of pimozide and fluphenazine in chronic schizophrenia.
Topics: Benzimidazoles; Blood Cell Count; Clinical Trials as Topic; Fluphenazine; Humans; Male; Middle Aged; | 1970 |
27 other studies available for fluphenazine and Parkinson Disease, Secondary
| Article | Year |
|---|---|
Fluphenazine-Induced Neurotoxicity with Acute Almost Transient Parkinsonism and Permanent Memory Loss: Lessons from a Case Report.
Topics: Adult; Amnesia; Antipsychotic Agents; Female; Fluphenazine; Humans; Memory Disorders; Parkinson Dise | 2023 |
Drug-induced extrapyramidal symptoms: their incidence and treatment.
Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Parasymp | 1967 |
Variation in oro-facial tardive dyskinesia during depot antipsychotic drug treatment.
Topics: Aged; Antipsychotic Agents; Delayed-Action Preparations; Dyskinesia, Drug-Induced; Female; Fluphenaz | 1983 |
An unusual effect of ECT on drug-induced parkinsonism and tardive dystonia.
Topics: Adult; Antipsychotic Agents; Dystonia; Electroconvulsive Therapy; Fluphenazine; Humans; Male; Parkin | 1995 |
Absence of parkinsonism among patients in long-term neuroleptic therapy who abuse cocaine.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Cocaine; Comorbidity; Delayed-Action Preparations; Flu | 1997 |
Factors related to tardive dyskinesia.
Topics: Adult; Age Factors; Aged; Antipsychotic Agents; Dyskinesia, Drug-Induced; Female; Fluphenazine; Foll | 1979 |
Letter: Parkinsonism induced by fluphenazine decanoate.
Topics: Fluphenazine; Humans; Parkinson Disease, Secondary; Schizophrenia; Time Factors | 1976 |
Iatrogenic morbidity in patients taking depot fluphenazine.
Topics: Adult; Age Factors; Aged; Akathisia, Drug-Induced; Basal Ganglia Diseases; Delayed-Action Preparatio | 1979 |
Fluphenazine enanthate in the outpatient treatment of late paraphrenia.
Topics: Aged; Ambulatory Care; Delayed-Action Preparations; Female; Fluphenazine; Haloperidol; Humans; Injec | 1979 |
Coexisting tardive dyskinesia and parkinsonism: a case report.
Topics: Acetylcholine; Adult; Benztropine; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Fluphenazine | 1977 |
Catatonic reactions to high-potency neuroleptic drugs.
Topics: Adolescent; Adult; Amantadine; Catatonia; Dose-Response Relationship, Drug; Female; Fluphenazine; Ha | 1977 |
[Treatment of schizophrenic psychoses with Lyorodin].
Topics: Acute Disease; Chronic Disease; Female; Fluphenazine; Humans; Male; Parkinson Disease, Secondary; Sc | 1977 |
Fluphenazine induced Parkinson-like syndrome in a horse.
Topics: Animals; Female; Fluphenazine; Horse Diseases; Horses; Parkinson Disease, Secondary | 1990 |
Long persisting drug-induced parkinsonism--a case report.
Topics: Adult; Chronic Disease; Delayed-Action Preparations; Female; Fluphenazine; Humans; Parkinson Disease | 1987 |
[Incidents and accidents during therapy with long-acting neuroleptics].
Topics: Amenorrhea; Autonomic Nervous System; Body Weight; Delayed-Action Preparations; Depression; Eye Mani | 1974 |
Effect of oral fluphenazine on Huntington's chorea.
Topics: Age Factors; Aged; Chronic Disease; Female; Fluphenazine; Humans; Huntington Disease; Male; Mental P | 1968 |
Reactions to fluphenazine hydrochloride by two adult male macaques.
Topics: Aggression; Animals; Behavior, Animal; Drinking Behavior; Drug Tolerance; Feeding Behavior; Fluphena | 1971 |
[Study of extrapyramidal manifestations induced by neuroleptics].
Topics: Antiparkinson Agents; Chlorpromazine; Drug Synergism; Extrapyramidal Tracts; Fluphenazine; Haloperid | 1972 |
Letter: Possible effects of combining phenothiazines.
Topics: Antiparkinson Agents; Drug Therapy, Combination; Fluphenazine; Humans; Male; Middle Aged; Parkinson | 1974 |
Fluphenazine-induced parkinsonism in the baboon: pharmacological and metabolic studies.
Topics: Animals; Basal Ganglia Diseases; Benztropine; Carbon Isotopes; Chromatography, Thin Layer; Feces; Fe | 1972 |
[Clinical experiences with a delayed-action preparation of fluphenazine].
Topics: Administration, Oral; Adult; Aged; Basal Ganglia Diseases; Bipolar Disorder; Climacteric; Delayed-Ac | 1972 |
The side-effects of fluphenazine decanoate.
Topics: Adolescent; Adult; Age Factors; Aged; Female; Fluphenazine; Follow-Up Studies; Humans; Hypotension; | 1973 |
[On the mode of action and the question of central organic late damages of continuous neuroleptic treatment].
Topics: Aged; Brain Stem; Butyrophenones; Central Nervous System; Cerebral Ventriculography; Extrapyramidal | 1966 |
[Clinical experience with fluphenazine decanoate in psychoses].
Topics: Adolescent; Adult; Depressive Disorder, Major; Female; Fluphenazine; Humans; Male; Middle Aged; Para | 1970 |
Long-acting, antipsychotic agents and extrapyramidal side effects.
Topics: Delayed-Action Preparations; Extrapyramidal Tracts; Fluphenazine; Humans; Movement Disorders; Parasy | 1970 |
The effectiveness of parenteral administration of fluphenazine decanoate in the treatment of chronic schizophrenics.
Topics: Administration, Oral; Adult; Biperiden; Chronic Disease; Female; Fluphenazine; Humans; Infusions, Pa | 1970 |
Dangers of fluphenazine.
Topics: Depression; Fluphenazine; Humans; Nausea; Parkinson Disease, Secondary; Vomiting | 1970 |