fluphenazine has been researched along with Neuroleptic Malignant Syndrome in 27 studies
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a case of neuroleptic malignant syndrome (NMS) associated with fluphenazine in a schizophrenic patient and review the literature related to this condition." | 7.73 | Fluphenazine-induced neuroleptic malignant syndrome in a schizophrenic patient. ( Aruna, AS; Murungi, JH, 2005) |
| "A mild form of neuroleptic malignant syndrome (NMS) in a schizophrenic patient who was receiving a depot neuroleptic is described and beneficial response to oral diazepam 50 mg daily is reported." | 7.67 | Treatment of a mild form of neuroleptic malignant syndrome with oral diazepam. ( Christodoulou, GN; Havaki-Kontaxaki, BJ; Kontaxakis, VP; Markidis, MP, 1988) |
| "To report a case of neuroleptic malignant syndrome (NMS) associated with fluphenazine in a schizophrenic patient and review the literature related to this condition." | 3.73 | Fluphenazine-induced neuroleptic malignant syndrome in a schizophrenic patient. ( Aruna, AS; Murungi, JH, 2005) |
| " We report the case of a 36 years old woman suffering from chronic schizophrenia and treated with flufenazine and olanzapine, who presented with series of generalised tonic-clonic seizures as the acute onset of recurrent malignant neuroleptic syndrome." | 3.73 | Series of seizures as a sign of development of recurrent malignant neuroleptic syndrome - a case report. ( Alvir, D; Kondić, L; Matijević, V; Supe, S, 2006) |
| "A mild form of neuroleptic malignant syndrome (NMS) in a schizophrenic patient who was receiving a depot neuroleptic is described and beneficial response to oral diazepam 50 mg daily is reported." | 3.67 | Treatment of a mild form of neuroleptic malignant syndrome with oral diazepam. ( Christodoulou, GN; Havaki-Kontaxaki, BJ; Kontaxakis, VP; Markidis, MP, 1988) |
| "In a schizophrenic patient, hypothermia was caused by combined treatment with zotepine, biperiden, and fluphenazine, although combined treatment with zotepine and biperiden had caused no side effects." | 3.67 | Hypothermia caused by antipsychotic drugs in a schizophrenic patient. ( Hashimoto, H; Kamimura, H; Nakajima, T; Nakao, J; Noto, T; Okamoto, K; Sugae, S, 1987) |
| "Though rare, neuroleptic malignant syndrome can occur in young adult females following use of antipsychotics, anaesthesia and surgery." | 1.48 | Neuroleptic malignant syndrome in a young adult female at the university of Benin Teaching Hospital: a case report. ( Agbonrofo, PI; Osakue, JE, 2018) |
| "Diphenhydramine 50 mg i." | 1.30 | Management of neuroleptic malignant syndrome with anticholinergic medication. ( Hasan, MY; Holmes, CH; Schauben, JL, 1999) |
| "The estimated prevalence of neuroleptic malignant syndrome in these psychiatric inpatients was 1." | 1.28 | Neuroleptic malignant syndrome in 12 of 9,792 Chinese inpatients exposed to neuroleptics: a prospective study. ( Chen, GQ; Deng, MZ; Phillips, MR, 1990) |
| "The neuroleptic malignant syndrome is an exceedingly rare but potentially fatal condition characterized by parkinsonian type rigidity, rise of temperature and altered consciousness." | 1.28 | An unusual presentation of neuroleptic malignant syndrome. ( Basu, J, 1991) |
| "The neuroleptic malignant syndrome is a serious complication associated with the use of antipsychotic drugs that has received a great deal of interest in recent times." | 1.28 | Neuroleptic malignant syndrome in organic brain disease and physical illness. ( Pilo, L, 1990) |
| "In a fatal case of neuroleptic malignant syndrome, a muscle sample taken within 1 h of death showed acute myopathic features with absence of muscle glycogen and neutral lipid." | 1.27 | Muscle pathology in the neuroleptic malignant syndrome. ( Martin, DT; Swash, M, 1987) |
| "The relationship between neuroleptic malignant syndrome (NMS) and malignant hyperthermia (MH) was investigated using the in vitro skeletal muscle contracture test to screen for MH-susceptibility in NMS patients." | 1.27 | Malignant hyperthermia susceptibility in neuroleptic malignant syndrome. ( Caroff, SN; Fletcher, JE; Heiman-Patterson, TD; Mann, SC; Rosenberg, H, 1987) |
| "The neuroleptic malignant syndrome is an uncommon but occasionally fatal reaction to antipsychotic medication characterized by fever, movement disorder, and stupor." | 1.27 | A case of neuroleptic malignant syndrome in a mentally retarded adolescent. ( Diamond, JM; Hayes, DD, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (40.74) | 18.7374 |
| 1990's | 10 (37.04) | 18.2507 |
| 2000's | 4 (14.81) | 29.6817 |
| 2010's | 2 (7.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agbonrofo, PI | 1 |
| Osakue, JE | 1 |
| Zivković, M | 1 |
| Mihaljević-Peles, A | 1 |
| Sagud, M | 1 |
| Silić, A | 1 |
| Mihanović, M | 1 |
| Tofler, IT | 1 |
| Ahmed, B | 1 |
| Aruna, AS | 1 |
| Murungi, JH | 1 |
| Supe, S | 1 |
| Matijević, V | 1 |
| Kondić, L | 1 |
| Alvir, D | 1 |
| Duggal, HS | 1 |
| Singh, I | 1 |
| Cape, G | 1 |
| Spivak, B | 1 |
| Gonen, N | 1 |
| Mester, R | 1 |
| Averbuch, E | 1 |
| Adlersberg, S | 1 |
| Weizman, A | 1 |
| Hasan, MY | 1 |
| Schauben, JL | 1 |
| Holmes, CH | 1 |
| Gönner, F | 1 |
| Baumgartner, R | 1 |
| Schüpbach, D | 1 |
| Merlo, MC | 1 |
| Lanczik, M | 1 |
| Fritze, J | 1 |
| Lazarus, A | 1 |
| Rosenberg, H | 2 |
| Deng, MZ | 1 |
| Chen, GQ | 1 |
| Phillips, MR | 1 |
| Basu, J | 1 |
| Pilo, L | 1 |
| Krystal, AD | 1 |
| McEvoy, JP | 1 |
| Keshavan, MS | 1 |
| Kambhampati, RK | 1 |
| Pope, HG | 1 |
| Cole, JO | 1 |
| Choras, PT | 1 |
| Fulwiler, CE | 1 |
| Maniam, T | 1 |
| Jamaluddin, J | 1 |
| Kyaw, O | 1 |
| Kontaxakis, VP | 1 |
| Christodoulou, GN | 1 |
| Markidis, MP | 1 |
| Havaki-Kontaxaki, BJ | 1 |
| Martin, DT | 1 |
| Swash, M | 1 |
| Rampertaap, MP | 1 |
| Caroff, SN | 1 |
| Fletcher, JE | 1 |
| Heiman-Patterson, TD | 1 |
| Mann, SC | 1 |
| Lesser, MS | 1 |
| Kahan, M | 1 |
| Brenner, R | 1 |
| Nayak, D | 1 |
| Diamond, JM | 1 |
| Hayes, DD | 1 |
| Noto, T | 1 |
| Hashimoto, H | 1 |
| Sugae, S | 1 |
| Okamoto, K | 1 |
| Nakao, J | 1 |
| Kamimura, H | 1 |
| Nakajima, T | 1 |
| Blue, MG | 1 |
| Schneider, SM | 1 |
| Noro, S | 1 |
| Fraley, DS | 1 |
1 review available for fluphenazine and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Neuroleptic malignant syndrome.
Topics: Adolescent; Adult; Benztropine; Bromocriptine; Catatonia; Child; Child, Preschool; Diagnosis, Differ | 1986 |
26 other studies available for fluphenazine and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Neuroleptic malignant syndrome in a young adult female at the university of Benin Teaching Hospital: a case report.
Topics: Adult; Antipsychotic Agents; Female; Fluphenazine; Humans; Intensive Care Units; Neuroleptic Maligna | 2018 |
The role of CYP2D6 and TaqI A polymorphisms in malignant neuroleptic syndrome: two case reports with three episodes.
Topics: Adult; Alleles; Antipsychotic Agents; Bipolar Disorder; Clozapine; Cytochrome P-450 CYP2D6; Dibenzot | 2010 |
Atypical (olanzapine) plus conventional (fluphenazine) neuroleptic treatment associated with the neuroleptic malignant syndrome.
Topics: Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Fluphenazine; Humans; Male; Middle | 2003 |
Fluphenazine-induced neuroleptic malignant syndrome in a schizophrenic patient.
Topics: Adult; Antipsychotic Agents; Fluphenazine; Humans; Injections, Intramuscular; Male; Neuroleptic Mali | 2005 |
Series of seizures as a sign of development of recurrent malignant neuroleptic syndrome - a case report.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Drug Therapy, Combination; Early Diag | 2006 |
Neuroleptic malignant syndrome presenting with acute renal failure.
Topics: Acute Kidney Injury; Antipsychotic Agents; Benzodiazepines; Electroencephalography; Female; Fluphena | 2008 |
Neuroleptic malignant syndrome--a cautionary tale and a surprising outcome.
Topics: Activities of Daily Living; Adaptation, Psychological; Adult; Antisocial Personality Disorder; Combi | 1994 |
Neuroleptic malignant syndrome associated with abrupt withdrawal of anticholinergic agents.
Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Fluphenazine; Humans; Male; Muscarinic Ant | 1996 |
Management of neuroleptic malignant syndrome with anticholinergic medication.
Topics: Adolescent; Benztropine; Cholinergic Antagonists; Diphenhydramine; Female; Fever; Fluphenazine; Huma | 1999 |
Neuroleptic malignant syndrome during low dosed neuroleptic medication in first-episode psychosis: a case report.
Topics: Adult; Antipsychotic Agents; Clozapine; Dantrolene; Female; Fluphenazine; Humans; Muscle Relaxants, | 1999 |
[Neuroleptic malignant syndrome--a case report].
Topics: Adult; Antipsychotic Agents; Drug Therapy, Combination; Fluphenazine; Humans; Male; Neuroleptic Mali | 1992 |
Treatment of rehospitalized NMS patients.
Topics: Adult; Antipsychotic Agents; Fluphenazine; Follow-Up Studies; Humans; Male; Neuroleptic Malignant Sy | 1990 |
Neuroleptic malignant syndrome in 12 of 9,792 Chinese inpatients exposed to neuroleptics: a prospective study.
Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; China; Confidence Intervals; Delayed-Action Prepa | 1990 |
An unusual presentation of neuroleptic malignant syndrome.
Topics: Adult; Dose-Response Relationship, Drug; Fluphenazine; Humans; Male; Neuroleptic Malignant Syndrome; | 1991 |
Neuroleptic malignant syndrome in organic brain disease and physical illness.
Topics: Adult; Brain Diseases; Female; Fluphenazine; Humans; Male; Middle Aged; Neuroleptic Malignant Syndro | 1990 |
Shared features of neuroleptic malignant syndrome and alcohol abuse complications.
Topics: Adult; Diagnosis, Differential; Ethanol; Fluphenazine; Humans; Male; Neuroleptic Malignant Syndrome; | 1990 |
Prolonged fever without extrapyramidal symptoms during neuroleptic treatment.
Topics: Adult; Basal Ganglia Diseases; Fluphenazine; Humans; Male; Neuroleptic Malignant Syndrome; Schizophr | 1989 |
Apparent neuroleptic malignant syndrome with clozapine and lithium.
Topics: Adult; Bipolar Disorder; Clozapine; Dibenzazepines; Drug Therapy, Combination; Fluphenazine; Humans; | 1986 |
Neuroleptic malignant syndrome--a study of 4 cases.
Topics: Adult; Autonomic Nervous System Diseases; Female; Fluphenazine; Haloperidol; Humans; Male; Neurolept | 1988 |
Treatment of a mild form of neuroleptic malignant syndrome with oral diazepam.
Topics: Administration, Oral; Adult; Diazepam; Drug Therapy, Combination; Fluphenazine; Humans; Injections, | 1988 |
Muscle pathology in the neuroleptic malignant syndrome.
Topics: Adult; Fluphenazine; Humans; Male; Muscles; Neuroleptic Malignant Syndrome; Procyclidine; Psychotic | 1987 |
Malignant hyperthermia susceptibility in neuroleptic malignant syndrome.
Topics: Adult; Disease Susceptibility; Female; Fluphenazine; Halothane; Humans; Male; Malignant Hyperthermia | 1987 |
Dantrolene sodium as a possible prophylactic agent against N.M.S.
Topics: Adult; Dantrolene; Fluphenazine; Humans; Male; Neuroleptic Malignant Syndrome; Recurrence; Schizophr | 1986 |
A case of neuroleptic malignant syndrome in a mentally retarded adolescent.
Topics: Adolescent; Aggression; Fluphenazine; Humans; Intellectual Disability; Male; Neuroleptic Malignant S | 1986 |
Hypothermia caused by antipsychotic drugs in a schizophrenic patient.
Topics: Adult; Biperiden; Dibenzothiepins; Drug Therapy, Combination; Fluphenazine; Humans; Hypothermia; Mal | 1987 |
Successful treatment of neuroleptic malignant syndrome with sodium nitroprusside.
Topics: Combined Modality Therapy; Female; Ferricyanides; Fluphenazine; Humans; Loxapine; Middle Aged; Neuro | 1986 |