fluphenazine has been researched along with Muscle Rigidity in 10 studies
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study was to find out whether the classic neuroleptic fluphenazine is a good model compound for inducing parkinsonian-like muscle rigidity in rats." | 7.70 | Muscle rigidity induced by fluphenazine in rats is antagonized by L-DOPA, an antiparkinsonian drug. ( Coper, H; Konieczny, J; Lorenc-Koci, E; Ossowska, K; Schulze, G; Wolfarth, S, 1998) |
| "A paranoid schizophrenic patient developed the neuroleptic malignant syndrome after receiving three doses of fluphenazine HCl and two doses of thioridazine while he was recovering from major trauma." | 7.66 | A case of neuroleptic malignant syndrome successfully treated with amantadine. ( Boettger, ML; McCarron, MM; Peck, JJ, 1982) |
| "Treatment with olanzapine moderately decreased, while treatment with fluphenazine significantly increased plasma cortisol levels and muscle rigidity." | 6.73 | The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study. ( Jakovljevic, M; Ljubicic, D; Marcinko, D; Mihaljevic-Peles, A; Muck-Seler, D; Mustapic, M; Pivac, N; Relja, M, 2007) |
| "The aim of the present study was to find out whether the classic neuroleptic fluphenazine is a good model compound for inducing parkinsonian-like muscle rigidity in rats." | 3.70 | Muscle rigidity induced by fluphenazine in rats is antagonized by L-DOPA, an antiparkinsonian drug. ( Coper, H; Konieczny, J; Lorenc-Koci, E; Ossowska, K; Schulze, G; Wolfarth, S, 1998) |
| "A paranoid schizophrenic patient developed the neuroleptic malignant syndrome after receiving three doses of fluphenazine HCl and two doses of thioridazine while he was recovering from major trauma." | 3.66 | A case of neuroleptic malignant syndrome successfully treated with amantadine. ( Boettger, ML; McCarron, MM; Peck, JJ, 1982) |
| "Treatment with olanzapine moderately decreased, while treatment with fluphenazine significantly increased plasma cortisol levels and muscle rigidity." | 2.73 | The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study. ( Jakovljevic, M; Ljubicic, D; Marcinko, D; Mihaljevic-Peles, A; Muck-Seler, D; Mustapic, M; Pivac, N; Relja, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Putzhammer, A | 1 |
| Perfahl, M | 1 |
| Pfeiff, L | 1 |
| Broll, K | 1 |
| Hess, L | 1 |
| Ibach, B | 1 |
| Jakovljevic, M | 1 |
| Pivac, N | 1 |
| Mihaljevic-Peles, A | 1 |
| Mustapic, M | 1 |
| Relja, M | 1 |
| Ljubicic, D | 1 |
| Marcinko, D | 1 |
| Muck-Seler, D | 1 |
| Schrader, G | 1 |
| Wong, C | 1 |
| Russell, R | 1 |
| Goldney, RD | 1 |
| Knezevic, W | 1 |
| Mastaglia, FL | 1 |
| Lefroy, RB | 1 |
| Fisher, A | 1 |
| Zubenko, G | 1 |
| Pope, HG | 1 |
| Pirovino, M | 1 |
| Meier, J | 1 |
| Meyer, M | 1 |
| Waldmeier, P | 1 |
| Schmid, M | 1 |
| McCarron, MM | 1 |
| Boettger, ML | 1 |
| Peck, JJ | 1 |
| Ossowska, K | 1 |
| Konieczny, J | 1 |
| Lorenc-Koci, E | 1 |
| Schulze, G | 1 |
| Coper, H | 1 |
| Wolfarth, S | 1 |
| Fabre, S | 1 |
| Gervais, C | 1 |
| Manuel, C | 1 |
| Vic Dupont, V | 1 |
| Meltzer, HY | 1 |
2 trials available for fluphenazine and Muscle Rigidity
| Article | Year |
|---|---|
[Alterations of gait parameters under external cueing in schizophrenic patients: a switch study].
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Exercise Test; Femal | 2004 |
The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Double-Blind Method; Female; Flu | 2007 |
8 other studies available for fluphenazine and Muscle Rigidity
| Article | Year |
|---|---|
The neuroleptic malignant syndrome.
Topics: Antipsychotic Agents; Cognition Disorders; Consciousness Disorders; Fever; Fluphenazine; Humans; Mal | 1981 |
Neuroleptic malignant syndrome.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Female; Fever; Fluphenazine; Haloperidol; Humans; Male | 1984 |
Management of a case of neuroleptic malignant syndrome with bromocriptine.
Topics: Adult; Antiparkinson Agents; Autonomic Nervous System Diseases; Bromocriptine; Fever; Fluphenazine; | 1983 |
[Malignant neuroleptics syndrome].
Topics: Adult; Amantadine; Baclofen; Cerebrospinal Fluid; Chromatography, Liquid; Cognition Disorders; Femal | 1984 |
A case of neuroleptic malignant syndrome successfully treated with amantadine.
Topics: Adult; Amantadine; Consciousness Disorders; Fluphenazine; Humans; Male; Malignant Hyperthermia; Musc | 1982 |
Muscle rigidity induced by fluphenazine in rats is antagonized by L-DOPA, an antiparkinsonian drug.
Topics: Animals; Antiparkinson Agents; Antipsychotic Agents; Dopamine Antagonists; Female; Fluphenazine; Lev | 1998 |
[Toxic syndrome induced by neuroleptics: report of 7 cases].
Topics: Adult; Female; Fluphenazine; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Rigidity; Syn | 1977 |
Rigidity, hyperpyrexia and coma following fluphenazine enanthate.
Topics: Adult; Basal Ganglia Diseases; Benztropine; Catatonia; Coma; Creatine Kinase; Female; Fever; Fluphen | 1973 |