fluphenazine has been researched along with Hyperprolactinemia in 6 studies
Hyperprolactinemia: Increased levels of PROLACTIN in the BLOOD, which may be associated with AMENORRHEA and GALACTORRHEA. Relatively common etiologies include PROLACTINOMA, medication effect, KIDNEY FAILURE, granulomatous diseases of the PITUITARY GLAND, and disorders which interfere with the hypothalamic inhibition of prolactin release. Ectopic (non-pituitary) production of prolactin may also occur. (From Joynt, Clinical Neurology, 1992, Ch36, pp77-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| " A 13-year-old female patient developed hyperprolactinemia with galactorrhea and amenorrhea while receiving thioridazine 300 mg daily." | 7.69 | Attenuation of antipsychotic-induced hyperprolactinemia with clozapine. ( Bunker, MT; Marken, PA; Ruehter, VL; Schneiderhan, ME, 1997) |
| "From December 2004 through March 2008, adult outpatients with a Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Edition diagnosis of schizophrenia or schizoaffective disorder who were taking haloperidol decanoate (n = 40) or fluphenazine decanoate (n = 22) were randomly assigned to stay on current long-acting injectable medication or switch to risperidone microspheres and followed for 6 months under study protocol and an additional 6 months naturalistic follow-up." | 5.16 | Effectiveness of switching from long-acting injectable fluphenazine or haloperidol decanoate to long-acting injectable risperidone microspheres: an open-label, randomized controlled trial. ( Covell, NH; Essock, SM; Jackson, CT; McEvoy, JP; Rojas, IA; Schooler, NR; Stroup, TS, 2012) |
| " A 13-year-old female patient developed hyperprolactinemia with galactorrhea and amenorrhea while receiving thioridazine 300 mg daily." | 3.69 | Attenuation of antipsychotic-induced hyperprolactinemia with clozapine. ( Bunker, MT; Marken, PA; Ruehter, VL; Schneiderhan, ME, 1997) |
| "Fluphenazine treatment affected sperm quality and male rats treated with fluphenazine sired fewer litters." | 1.33 | Hyperprolactinemia affects spermiogenesis in adult male rats. ( Aleem, M; Balasinor, N; Choudhari, J; Gill-Sharma, MK; Padwal, V; Parte, P, 2005) |
| "Hyperprolactinemia is a known side-effect of fluphenazine, a broad spectrum, long-acting phenothiazine known to be D2 dopamine receptor antagonist." | 1.32 | Antifertility effects of fluphenazine in adult male rats. ( Aleem, M; Balasinor, N; Choudhary, J; D'Souza, S; Gill-Sharma, MK; Juneja, HS; Padwal, V; Parte, P; Sethi, G, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Covell, NH | 1 |
| McEvoy, JP | 1 |
| Schooler, NR | 1 |
| Stroup, TS | 1 |
| Jackson, CT | 1 |
| Rojas, IA | 1 |
| Essock, SM | 1 |
| Gill-Sharma, MK | 2 |
| Aleem, M | 2 |
| Sethi, G | 1 |
| Choudhary, J | 1 |
| Padwal, V | 2 |
| D'Souza, S | 1 |
| Balasinor, N | 2 |
| Parte, P | 2 |
| Juneja, HS | 1 |
| Choudhari, J | 1 |
| Bunker, MT | 1 |
| Marken, PA | 1 |
| Schneiderhan, ME | 1 |
| Ruehter, VL | 1 |
| Oliveira, MC | 1 |
| Messinger, HP | 1 |
| Tannhauser, M | 1 |
| Barbosa-Coutinho, L | 1 |
| Prysor-Jones, RA | 1 |
| Silverlight, JJ | 1 |
| Jenkins, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Switching Antipsychotic Medications[NCT00044655] | Phase 4 | 219 participants (Actual) | Interventional | 2001-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00044655)
Timeframe: Measured at Six Months
| Intervention | participants (Number) |
|---|---|
| Stay | 11 |
| Switch | 23 |
1 trial available for fluphenazine and Hyperprolactinemia
| Article | Year |
|---|---|
Effectiveness of switching from long-acting injectable fluphenazine or haloperidol decanoate to long-acting injectable risperidone microspheres: an open-label, randomized controlled trial.
Topics: Antipsychotic Agents; Connecticut; Delayed-Action Preparations; Drug Substitution; Female; Fluphenaz | 2012 |
5 other studies available for fluphenazine and Hyperprolactinemia
| Article | Year |
|---|---|
Antifertility effects of fluphenazine in adult male rats.
Topics: Animals; Disease Models, Animal; Dopamine Antagonists; Embryo Implantation; Female; Fertility; Fluph | 2003 |
Hyperprolactinemia affects spermiogenesis in adult male rats.
Topics: Animals; Antipsychotic Agents; Blotting, Western; Chromosomal Proteins, Non-Histone; Cyclic AMP; Cyc | 2005 |
Attenuation of antipsychotic-induced hyperprolactinemia with clozapine.
Topics: Adolescent; Amenorrhea; Antipsychotic Agents; Bromocriptine; Clozapine; Female; Fluphenazine; Galact | 1997 |
Chronic effect of antidopaminergic drugs or estrogen on male wistar rat lactotrophs and somatotrophs.
Topics: Animals; Dopamine Antagonists; Estrogens; Fluphenazine; Growth Hormone; Haloperidol; Hyperprolactine | 1999 |
Hyperprolactinemia reduces vasoactive intestinal peptide in the anterior pituitary glands of rats.
Topics: Animals; Bromocriptine; Drug Implants; Estradiol; Female; Fluphenazine; Hyperprolactinemia; Pituitar | 1987 |