fluphenazine has been researched along with Huntington Disease in 7 studies
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Biochemical bases of Huntington's Chorea are discussed." | 1.26 | [Cerebrospinal fluid metabolism of biogenic amines in Huntington chorea]. ( Abbruzzese, G; Albano, C; Canini, S; Lamedica, G; Loeb, C; Roccatagliata, G, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roccatagliata, G | 2 |
| Albano, C | 2 |
| Folstein, S | 1 |
| Folstein, M | 1 |
| Terrence, CF | 1 |
| Loeb, C | 1 |
| Lamedica, G | 1 |
| Abbruzzese, G | 1 |
| Canini, S | 1 |
| Korenyi, C | 2 |
| Whittier, JR | 2 |
| Mattsson, B | 1 |
| Persson, SA | 1 |
1 trial available for fluphenazine and Huntington Disease
| Article | Year |
|---|---|
Fluphenazine decanoate in the treatment of chorea: a double-blind study.
Topics: Adult; Clinical Trials as Topic; Delayed-Action Preparations; Female; Fluphenazine; Humans; Huntingt | 1976 |
6 other studies available for fluphenazine and Huntington Disease
| Article | Year |
|---|---|
[Therapy of Huntington's chorea: a pharmacological and clinical approach to the organization of the basal ganglia].
Topics: Adult; Aged; Baclofen; Basal Ganglia; Behavior; Biperiden; Bromocriptine; Female; Fluphenazine; Homo | 1980 |
Diagnosis and treatment of Huntington's disease.
Topics: Affective Symptoms; Amitriptyline; Chlorpromazine; Cognition Disorders; Counseling; Deglutition Diso | 1981 |
[Cerebrospinal fluid metabolism of biogenic amines in Huntington chorea].
Topics: Adult; Aged; Biogenic Amines; Dopamine; Female; Fluphenazine; Humans; Huntington Disease; Male; Midd | 1976 |
Drug treatment in 117 cases of Huntington's disease with special reference to fluphenazine (Prolixin).
Topics: Adult; Female; Fluphenazine; Humans; Huntington Disease; Male; Middle Aged | 1967 |
Effect of oral fluphenazine on Huntington's chorea.
Topics: Age Factors; Aged; Chronic Disease; Female; Fluphenazine; Humans; Huntington Disease; Male; Mental P | 1968 |
Cerebrospinal homovanillic acid and 5-hydroxyindoleacetic acid in huntington's chorea.
Topics: Adult; Chlormethiazole; Chlorpromazine; Female; Fluphenazine; Haloperidol; Homovanillic Acid; Humans | 1974 |