fluphenazine has been researched along with Hepatolenticular Degeneration in 1 studies
Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Wilson disease is a hereditary disorder caused by mutations of the ATP7B gene, which leads to intoxication with copper as a result of an unbalance of copper homeostasis." | 1.39 | [Copper intoxication decreases lifespan and induces neurologic alterations in Drosophila melanogaster]. ( Arcaya, JL; Salazar, U; Silva, EJ; Tejeda, CM; Urdaneta, K; Varela, K, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arcaya, JL | 1 |
| Tejeda, CM | 1 |
| Salazar, U | 1 |
| Silva, EJ | 1 |
| Urdaneta, K | 1 |
| Varela, K | 1 |
1 other study available for fluphenazine and Hepatolenticular Degeneration
| Article | Year |
|---|---|
[Copper intoxication decreases lifespan and induces neurologic alterations in Drosophila melanogaster].
Topics: Age Factors; Animals; Copper Sulfate; Disease Models, Animal; Disease Progression; Dopamine Agents; | 2013 |